FOLR1 antibody

Catalog No. ABIN7248695

Product Details anti-FOLR1 Antibody

Target: FOLR1 (Folate Receptor 1 (Adult) (FOLR1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOLR1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human FOLR1

Isotype: IgG

Application Details

Application Notes: IHC 1:40-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.28 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FOLR1

Target: FOLR1 (Folate Receptor 1 (Adult) (FOLR1))

Alternative Name: FOLR1 (FOLR1 Products)

Synonyms: FBP antibody, FOLR antibody, fbp antibody, folr antibody, folr1 antibody, FBP1 antibody, Folbp-1 antibody, Folbp1 antibody, Fbp1 antibody, FOLR1 antibody, Folr1 antibody, folate receptor 1 antibody, folate receptor 1 (adult) antibody, folate receptor 1 (adult) L homeolog antibody, zgc:165502 antibody, Folate receptor alpha antibody, folate receptor alpha antibody, FOLR1 antibody, folr1 antibody, folr1.L antibody, zgc:165502 antibody, Folr1 antibody, LOC100066084 antibody, LOC100725439 antibody

Background: Folate receptor 1 (FOLR1),also known as folate receptor alpha or adult folate-binding protein (FBP),is a 38- kDa glycoprotein belonging to the folate receptor family . The receptor binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. FOLR1 is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. FOLR1 expression is often limited to the apical surfaces of epithelium in the lung,kidney and choroid plexus but is differentially overexpressed in a variety of solid tumors such as ovarian cancer,non-small cell lung cancer,breast cancer,kidney cancer and high-grade osteosarcoma .

UniProt: P15328

Pathways: Dicarboxylic Acid Transport