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anti-Fused in Sarcoma (FUS) Antibodies

FUS encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. Additionally we are shipping FUS Kits (9) and FUS Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FUS 2521 P35637
FUS 233908 P56959
FUS 317385  
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Top anti-FUS Antibodies at antibodies-online.com

Showing 10 out of 56 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, IF, IHC (p), WB Flow cytometric analysis of Hela cells using FUS Antibody (C-term) Cat.-No AP51735PU-N (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Confocal immunofluorescent analysis of FUS Antibody (C-term) Cat.-No AP51735PU-N with MDA-MB231 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated IF, WB Western blot analysis of TLS on a Jurkat cell lysate. Lane 1: 1:250, Lane 2: 1:500, Lane 3: 1:1000 dilution of the anti- TLS antibody. 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Rabbit Un-conjugated IHC (p), IP, WB 50 μL Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated IHC (p), WB Human Small Intestine (formalin-fixed, paraffin-embedded) stained with FUS antibody ABIN462224 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Breast (formalin-fixed, paraffin-embedded) stained with FUS antibody ABIN462224 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 100 μL Log in to see 8 to 10 Days
$390.50
Details
Human Rabbit Alkaline Phosphatase (AP) ICC, FACS, IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated IF, IHC, WB   100 μL Log in to see 8 to 10 Days
$522.50
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated IHC   100 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB   50 μL Log in to see 8 to 10 Days
$463.83
Details

FUS Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-FUS Antibodies

  1. Human Polyclonal FUS Primary Antibody for ICC, IF - ABIN151997 : Neumann, Rademakers, Roeber, Baker, Kretzschmar, Mackenzie: A new subtype of frontotemporal lobar degeneration with FUS pathology. in Brain : a journal of neurology 2009 (PubMed)
    Show all 12 references for ABIN151997

  2. Human Polyclonal FUS Primary Antibody for ICC, IF - ABIN151993 : Hume, Sasmono, Himes, Sharma, Bronisz, Constantin, Ostrowski, Ross: The Ewing sarcoma protein (EWS) binds directly to the proximal elements of the macrophage-specific promoter of the CSF-1 receptor (csf1r) gene. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
    Show all 7 references for ABIN151993

  3. Human Monoclonal FUS Primary Antibody for IF, WB - ABIN968508 : Hallier, Lerga, Barnache, Tavitian, Moreau-Gachelin: The transcription factor Spi-1/PU.1 interacts with the potential splicing factor TLS. in The Journal of biological chemistry 1998 (PubMed)
    Show all 5 references for ABIN968508

  4. Human Polyclonal FUS Primary Antibody for ICC, IF - ABIN251039 : Vance, Scotter, Nishimura, Troakes, Mitchell, Kathe, Urwin, Manser, Miller, Hortobágyi, Dragunow, Rogelj, Shaw: ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules. in Human molecular genetics 2013 (PubMed)
    Show all 3 references for ABIN251039

  5. Human Polyclonal FUS Primary Antibody for ICC, IF - ABIN151994 : Tan, Manley: TLS inhibits RNA polymerase III transcription. in Molecular and cellular biology 2009 (PubMed)
    Show all 3 references for ABIN151994

  6. Human Polyclonal FUS Primary Antibody for EIA, FACS - ABIN952406 : Kim, Shanware, Bowler, Tibbetts: Amyotrophic lateral sclerosis-associated proteins TDP-43 and FUS/TLS function in a common biochemical complex to co-regulate HDAC6 mRNA. in The Journal of biological chemistry 2010 (PubMed)
    Show all 2 references for ABIN952406

  7. Chicken Polyclonal FUS Primary Antibody for IHC, WB - ABIN2778717 : Sato, Idogawa, Honda, Fujii, Kawashima, Takekuma, Hoshika, Hirohashi, Yamada: Beta-catenin interacts with the FUS proto-oncogene product and regulates pre-mRNA splicing. in Gastroenterology 2005 (PubMed)

More Antibodies against FUS Interaction Partners

Human Fused in Sarcoma (FUS) interaction partners

  1. The results of this study suggested that FUS mutations are the most frequent genetic cause in early-onset sporadic ALS patients of Chinese origin.

  2. Data show that induced pluripotent stem cells (iPSC)-derived motor neurons mimicked several neurodegenerative phenotypes including mis (show AMH Antibodies)-localization of fused-in sarcoma (FUS) gene product into cytosolic.

  3. miR (show MLXIP Antibodies)-141 and the FUS gene, which are inversely correlated, play significant functional roles in regulating human neuroblastoma (show ARHGEF16 Antibodies).

  4. pathological TDP-43 (show TARDBP Antibodies) and FUS may exert motor neuron pathology in amyotrophic lateral sclerosis through the initiation of propagated misfolding of SOD1 (show SOD1 Antibodies)

  5. iNeurons may provide a more reliable model for investigating FUS mutations with disrupted NLS (show ALDH1A2 Antibodies) for understanding FUS-associated proteinopathies in amyotrophic lateral sclerosis

  6. A subset of juvenile-onset familial/sporadic ALS (show IGFALS Antibodies) cases with FUS gene mutations reportedly demonstrates mental retardation or learning difficulty.

  7. Study implicates phosphorylation as an additional mechanism by which nuclear transport of FUS might be regulated and potentially perturbed in ALS and FTLD.

  8. prevalence of the FUS-ERG (show ERG Antibodies) gene fusion in a large cohort of pathologically and molecularly well characterized small blue round cell tumors, lacking other known gene rearrangements

  9. Study identifies a common mechanism of transport into neurites of proteins linked to the pathology of Alzheimer's disease (i.e. sAPP) and ALS (show IGFALS Antibodies) (i.e. FUS, TDP-43 (show TARDBP Antibodies) and SOD1 (show SOD1 Antibodies))

  10. RNA binding proteins TDP-43 (show TARDBP Antibodies) and FUS do not consistently fit the currently characterised inclusion models suggesting that cells have a larger repertoire for generating inclusions than currently thought.

Mouse (Murine) Fused in Sarcoma (FUS) interaction partners

  1. The data of this study support the notion that expression of cytoplasmically mislocalized FUS with compromised RNA-binding capacity causes particularly prominent and harmful FUS pathology in the mouse nervous system.

  2. These results highlight the pivotal role of FUS in regulating GluA1 (show GRIA1 Antibodies) mRNA stability, post-synaptic function and fronto-temporal lobar degeneration-like animal behaviors.

  3. these studies establish potentially converging disease mechanisms in amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy, with ALS-causative mutants acquiring properties representing both gain and loss of function.

  4. FUS/TLS depletion causes phenotypes possibly related to neuropsychiatric and neurodegenerative conditions, but distinct from ALS and ET, together with specific alterations in RNA metabolisms.

  5. It is associated with amyotrophic lateral sclerosis and its mutation causes accumulation of fus positive stress granules in neurons.

  6. Study provides evidence for loss of PRMT1 (show PRMT1 Antibodies) function as a consequence of cytoplasmic accumulation of FUS in the pathogenesis of amyotrophic lateral sclerosis, including changes in the histone code regulating gene transcription.

  7. our study provided evidence that a multistep process of FUS aggregation in the cell cytoplasm includes RNA-dependent and RNA-independent mechanisms.

  8. Activation of metabotropic glutamate (show GRIN1 Antibodies) receptors 1/5 in neocortical slices and isolated synaptoneurosomes increases endogenous mouse FUS and FUS(WT) protein levels but decreases the FUS(R521G) protein

  9. Study shows that neuronal aggregates formed by mutant FUS protein may aberrantly sequester survival motor neuron protein (SMN (show SMN1 Antibodies)) and concomitantly cause a reduction of SMN (show STMN1 Antibodies) levels in the axon, leading to axonal defects.

  10. FUS is a coregulator of MITF (show MITF Antibodies) activity and provide new insights into how the RANKL (show TNFSF11 Antibodies)/p38 MAPK (show MAPK14 Antibodies) signaling nexus controls gene expression in osteoclasts.

FUS Antigen Profile

Protein Summary

This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.

Gene names and symbols associated with anti-Fused in Sarcoma (FUS) Antibodies

  • fused in sarcoma (FUS) antibody
  • fused in sarcoma (Fus) antibody
  • ALS6 antibody
  • D430004D17Rik antibody
  • D930039C12Rik antibody
  • ETM4 antibody
  • FUS/TLS antibody
  • Fus1 antibody
  • HNRNPP2 antibody
  • POMP75 antibody
  • Tls antibody

Protein level used designations for anti-Fused in Sarcoma (FUS) Antibodies

75 kDa DNA-pairing protein , RNA-binding protein FUS , fus-like protein , fusion gene in myxoid liposarcoma , heterogeneous nuclear ribonucleoprotein P2 , oncogene FUS , oncogene TLS , translocated in liposarcoma protein , fusion, derived from t(12;16) malignant liposarcoma , hnRNP P2 , pigpen protein , protein pigpen , translocated in liposarcoma , fusion , pigpen , fusion (involved in t(12;16) in malignant liposarcoma) , 16) in malignant liposarcoma) , 16) malignant liposarcoma , fusion (involved in t(12 , fusion, derived from t(12

GENE ID SPECIES
2521 Homo sapiens
233908 Mus musculus
414144 Gallus gallus
280796 Bos taurus
317385 Rattus norvegicus
479778 Canis lupus familiaris
Selected quality suppliers for anti-FUS (FUS) Antibodies
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