FUS antibody (C-Term)

Catalog No. ABIN654146

The Rabbit Polyclonal anti-FUS antibody is suitable to detect FUS in samples from Human and Mouse. It has been validated for WB, IF, FACS and IHC (p).

Quick Overview for FUS antibody (C-Term) (ABIN654146)

Target: FUS (Fused in Sarcoma (FUS))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FUS antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB23928

Product Details anti-FUS Antibody

Binding Specificity: AA 499-526, C-Term

Predicted Reactivity: B

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FUS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 499-526 amino acids from the C-terminal region of human FUS.

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for FUS

Target: FUS (Fused in Sarcoma (FUS))

Alternative Name: FUS

Background: This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.

Molecular Weight: 53426

Gene ID: 2521

NCBI Accession: NP_001164105, NP_004951

UniProt: P35637