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anti-Gap Junction Protein, alpha 5, 40kDa (GJA5) Antibodies

GJA5 is a member of the connexin gene family. Additionally we are shipping GJA5 Kits (36) and GJA5 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GJA5 50563 P28234
GJA5 14613 Q01231
GJA5 2702 P36382
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Top anti-GJA5 Antibodies at antibodies-online.com

Showing 10 out of 78 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Dog Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat myocardium tissue labeled with Anti-Connexin-40 Polyclonal Antibody, Unconjugated (ABIN736926) at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-GJA5 N-term Pab (ABIN388375) in Placenta lysate. GJA5 (Arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with GJA5 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Mouse Un-conjugated IHC (fro), IHC (p), ELISA, WB Anti-GJA5 / Connexin 40 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1101760 concentration 20 ug/ml. 50 μg Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-Connexin 40/GJA5 antibody, Western blotting Lane 1: Mouse Heart Tissue Lysate Lane 2: Mouse Heart Tissue Lysate Anti-Connexin 40/GJA5 antibody, IHC(P) IHC(P): Rat Cardiac Muscle Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IHC (p), WB Human Heart (formalin-fixed, paraffin-embedded) stained with GJA5 antibody ABIN214764 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB GJA5 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Rat Rabbit Un-conjugated ELISA, WB   50 μg Log in to see 8 to 10 Days
$610.50
Details

GJA5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-GJA5 Antibodies

  1. Human Polyclonal GJA5 Primary Antibody for EIA, WB - ABIN357093 : Dupays, Mazurais, Rücker-Martin, Calmels, Bernot, Cronier, Malassiné, Gros, Théveniau-Ruissy: Genomic organization and alternative transcripts of the human Connexin40 gene. in Gene 2003 (PubMed)
    Show all 5 references for ABIN357093

  2. Cow (Bovine) Polyclonal GJA5 Primary Antibody for WB - ABIN2774859 : Makita, Sasaki, Groenewegen, Yokota, Yokoshiki, Murakami, Tsutsui: Congenital atrial standstill associated with coinheritance of a novel SCN5A mutation and connexin 40 polymorphisms. in Heart rhythm : the official journal of the Heart Rhythm Society 2005 (PubMed)

  3. Dog (Canine) Polyclonal GJA5 Primary Antibody for IF (p), IHC (p) - ABIN736926 : Zhao, Xu, Yun, Zhao, Li, Gong, Yuan, Yan, Zhang, Ding, Wang, Zhang, Dong, Xiu, Yang, Liu, Xue, Li: Chronic obstructive sleep apnea causes atrial remodeling in canines: mechanisms and implications. in Basic research in cardiology 2014 (PubMed)

More Antibodies against GJA5 Interaction Partners

Mouse (Murine) Gap Junction Protein, alpha 5, 40kDa (GJA5) interaction partners

  1. High-fat diet increases vulnerability to atrial arrhythmia by down-regulation of Cx40 via miR (show MLXIP Antibodies)-27b.

  2. Report interaction between ALK1 (show ACVRL1 Antibodies) signaling and connexin40 in the development of arteriovenous malformations.

  3. Cx40 is a requirement for the pressure control of renin (show REN Antibodies) secretion irrespective of the localization of renin (show REN Antibodies) secreting cells.

  4. Cx37 (show GJA4 Antibodies) is more markedly involved in basal NO release, release of cyclooxygenase products and the regulation of the sensitivity for Acetylcholine as compared to Cx40.

  5. This study showed the progressive changes of Cx 40 at protein and mRNA levels in the mouse hippocampus during and after pilocarpine-induced status epilepticus.

  6. Cx40 and Cx37 (show GJA4 Antibodies) play an in vivo role in the regulation of eNOS (show NOS3 Antibodies).

  7. Endothelial connexin 40, but not connexin 37 (show GJA4 Antibodies), is implicated in resistance of the heart to ischaemia/reperfusion injury by activation of the CD73 pathway

  8. Data indicate the role of renin (show REN Antibodies) in hypertension linked to loss of connexin 40 (Cx40).

  9. connecxin 40 contributes to the propagation Ca2 (show CA2 Antibodies)+ signaling triggered by Acetylcholine in endothelial cells expressing the M3 muscarinic receptors.

  10. genetic polymorphisms in endothelial Cx40 can contribute to the pathogenesis of arterial disease.

Human Gap Junction Protein, alpha 5, 40kDa (GJA5) interaction partners

  1. This is a review summarizing atrial fibrillation-linked somatic and germline mutations in the gene encoding Cx40. Multiple impairments were observed in these mutants, including impaired gap junction function by abnormal localization or function, as well as increased hemichannel function.

  2. Human atrial myocytes express Cx40 and Cx43 (show GJA1 Antibodies). However, in vitro expression study indicates that human Cx40 is not able to dock with Cx43 (show GJA1 Antibodies) to form heterotypic gap junction channels. This study designed two Cx40 variants, D55N or P193Q. Both of them were successful in forming functional heterotypic gap junction channels with Cx43 (show GJA1 Antibodies).

  3. Two polymorphisms in the Cx40 promoter are associated with hypertension and left ventricular hypertrophy preferentially in men.

  4. Report interaction between ALK1 (show ACVRL1 Antibodies) signaling and connexin40 in the development of arteriovenous malformations.

  5. Reduced Cx40 levels and heterogeneity of its distribution (relative to Cx43 (show GJA1 Antibodies)) are common in atrial fibrillation.

  6. Two atrial fibrillation-linked germline Cx40 mutants, V85I and L221I, were investigated.

  7. These findings provide evidence that the connexin 40 Q49X mutant is capable of impairing gap-junction distribution and function of key atrial connexins, which might play a role in the predisposition to and onset of atrial fibrillation.

  8. 17-beta-estradiol modulates connexins and integrins as well as ER-beta (show ESR2 Antibodies) expression induced by high frequency electromagnetic fields.

  9. 4 novel heterozygous GJA5 mutations, p.K107R, p.L223M, p.Q236H and p.I257L, were identified in 4 of 310 unrelated AF patients.

  10. the germline familial mutations in Cx40 impair the gap junctions through different mechanisms, which may predispose the mutant carriers to AF.

GJA5 Antigen Profile

Protein Summary

This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene may be associated with atrial fibrillation. Alternatively spliced transcript variants encoding the same isoform have been described.

Gene names and symbols associated with GJA5

  • gap junction protein, alpha 5 (Gja5) antibody
  • gap junction protein, alpha 5, 40kDa (GJA5) antibody
  • 5730555N10Rik antibody
  • ATFB11 antibody
  • Cnx40 antibody
  • CX40 antibody
  • Gja-5 antibody

Protein level used designations for GJA5

connexin 40 , connexin-40 , gap junction alpha-5 protein , gap junction membrane channel protein alpha 5 , gap junction protein alpha 5 , gap junction protein, alpha 5, 40kDa (connexin 40) , cx40 , connexin-42 , cx42

GENE ID SPECIES
50563 Rattus norvegicus
14613 Mus musculus
2702 Homo sapiens
483155 Canis lupus familiaris
539491 Bos taurus
396502 Gallus gallus
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