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GJA5 is a member of the connexin gene family. Additionally we are shipping GJA5 Kits (25) and GJA5 Proteins (6) and many more products for this protein.
Showing 10 out of 79 products:
Human Polyclonal GJA5 Primary Antibody for EIA, WB - ABIN357093
Dupays, Mazurais, Rücker-Martin, Calmels, Bernot, Cronier, Malassiné, Gros, Théveniau-Ruissy: Genomic organization and alternative transcripts of the human Connexin40 gene. in Gene 2003
Show all 5 references for ABIN357093
Cow (Bovine) Polyclonal GJA5 Primary Antibody for WB - ABIN2774859
Makita, Sasaki, Groenewegen, Yokota, Yokoshiki, Murakami, Tsutsui: Congenital atrial standstill associated with coinheritance of a novel SCN5A mutation and connexin 40 polymorphisms. in Heart rhythm : the official journal of the Heart Rhythm Society 2005
Dog (Canine) Polyclonal GJA5 Primary Antibody for IF (p), IHC (p) - ABIN736926
Zhao, Xu, Yun, Zhao, Li, Gong, Yuan, Yan, Zhang, Ding, Wang, Zhang, Dong, Xiu, Yang, Liu, Xue, Li: Chronic obstructive sleep apnea causes atrial remodeling in canines: mechanisms and implications. in Basic research in cardiology 2014
High-fat diet increases vulnerability to atrial arrhythmia by down-regulation of Cx40 via miR (show MLXIP Antibodies)-27b.
Report interaction between ALK1 (show ACVRL1 Antibodies) signaling and connexin40 in the development of arteriovenous malformations.
Cx40 is a requirement for the pressure control of renin (show REN Antibodies) secretion irrespective of the localization of renin (show REN Antibodies) secreting cells.
Cx37 (show GJA4 Antibodies) is more markedly involved in basal NO release, release of cyclooxygenase products and the regulation of the sensitivity for Acetylcholine as compared to Cx40.
This study showed the progressive changes of Cx 40 at protein and mRNA levels in the mouse hippocampus during and after pilocarpine-induced status epilepticus.
Cx40 and Cx37 (show GJA4 Antibodies) play an in vivo role in the regulation of eNOS (show NOS3 Antibodies).
Endothelial connexin 40, but not connexin 37 (show GJA4 Antibodies), is implicated in resistance of the heart to ischaemia/reperfusion injury by activation of the CD73 pathway
Data indicate the role of renin (show REN Antibodies) in hypertension linked to loss of connexin 40 (Cx40).
connecxin 40 contributes to the propagation Ca2 (show CA2 Antibodies)+ signaling triggered by Acetylcholine in endothelial cells expressing the M3 muscarinic receptors.
genetic polymorphisms in endothelial Cx40 can contribute to the pathogenesis of arterial disease.
Cx 40 (rs35594137) was associated with atrial fibrillation; in the Uygur population, Cx 40 (rs35594137) should be considered as an independent risk factor for patients with atrial fibrillation, who might have racial differences in rs35594137 variant frequencies
This is a review summarizing atrial fibrillation-linked somatic and germline mutations in the gene encoding Cx40. Multiple impairments were observed in these mutants, including impaired gap junction function by abnormal localization or function, as well as increased hemichannel function.
Human atrial myocytes express Cx40 and Cx43 (show GJA1 Antibodies). However, in vitro expression study indicates that human Cx40 is not able to dock with Cx43 (show GJA1 Antibodies) to form heterotypic gap junction channels. This study designed two Cx40 variants, D55N or P193Q. Both of them were successful in forming functional heterotypic gap junction channels with Cx43 (show GJA1 Antibodies).
Two polymorphisms in the Cx40 promoter are associated with hypertension and left ventricular hypertrophy preferentially in men.
Reduced Cx40 levels and heterogeneity of its distribution (relative to Cx43 (show GJA1 Antibodies)) are common in atrial fibrillation.
Two atrial fibrillation-linked germline Cx40 mutants, V85I and L221I, were investigated.
These findings provide evidence that the connexin 40 Q49X mutant is capable of impairing gap-junction distribution and function of key atrial connexins, which might play a role in the predisposition to and onset of atrial fibrillation.
17-beta-estradiol modulates connexins and integrins as well as ER-beta (show ESR2 Antibodies) expression induced by high frequency electromagnetic fields.
4 novel heterozygous GJA5 mutations, p.K107R, p.L223M, p.Q236H and p.I257L, were identified in 4 of 310 unrelated AF patients.
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene may be associated with atrial fibrillation. Alternatively spliced transcript variants encoding the same isoform have been described.
, gap junction alpha-5 protein
, gap junction membrane channel protein alpha 5
, gap junction protein alpha 5
, gap junction protein, alpha 5, 40kDa (connexin 40)