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Cullin 2 Antibodies

(Cullin 2 (CUL2))
Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. May serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (By similarity). The functional specificity of the ECS complex depends on the substrate recognition component. ECS(VHL) mediates the ubiquitination of hypoxia-inducible factor (HIF).
Cullin 2 antibody  (C-Term) Cullin 2 antibody  (C-Term) Cullin 2 antibody (C-Term) (ABIN6261115)

CUL2 Reactivity: Human, Mouse, Rat ELISA, ICC, IF, IHC, WB Host: Rabbit Polyclonal unconjugated

Cullin 2 antibody  (Middle Region) Cullin 2 antibody  (Middle Region) Cullin 2 antibody (Middle Region) (ABIN3030577)

CUL2 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated

Cullin 2 antibody Cullin 2 antibody Cullin 2 antibody (ABIN7180925)

CUL2 Reactivity: Human ELISA, IF, IHC, WB Host: Rabbit Polyclonal unconjugated

Cullin 2 Antibodies by Grade

Find Cullin 2 Antibodies with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

Cullin 2 Antibodies by Reactivity

Find Cullin 2 Antibodies for a variety of species such as anti-Human Cullin 2, anti-Mouse Cullin 2, anti-Rat Cullin 2. The species listed below are among those available. Click on a link to go to the corresponding products.

Cullin 2 Antibodies by Application

Find Cullin 2 Antibodies validated for a specific application such as WB, ELISA, IHC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

Cullin 2 Antibodies by Host

Find Cullin 2 Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

Cullin 2 Antibodies by Binding Specificity

Find Cullin 2 Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

Cullin 2 Antibodies by Clonality

Find available monoclonal or polyclonal Cullin 2 Antibodies. Click on a link to go to the corresponding products.

Cullin 2 Antibodies by Clone

Find Cullin 2 Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

Cullin 2 Antibodies by Conjugate

Find Cullin 2 Antibodies with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Cullin 2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Rat
Application WB
Validations
  • (3)
Cat. No. ABIN3043009
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application IF, IHC, ELISA, WB
Validations
  • (3)
Cat. No. ABIN1533245
Quantity 100 μg
Datasheet Datasheet
Reactivity Chicken, Cow, Dog, Human, Mouse, Pig, Rat
Application IC, IF, IHC, WB
Validations
  • (3)
Cat. No. ABIN2704686
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, IHC, WB
Validations
  • (2)
Cat. No. ABIN7184770
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, WB
Validations
  • (2)
Cat. No. ABIN7148749
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IF, IHC, WB
Validations
  • (2)
Cat. No. ABIN3184130
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC, WB
Validations
  • (2)
Cat. No. ABIN571170
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application IF, IHC
Validations
  • (2)
Cat. No. ABIN7260691
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application IP, WB
Validations
  • (4)
  • (1)
Cat. No. ABIN233771
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, WB
Validations
  • (2)
Cat. No. ABIN7266542
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
  • (1)
Cat. No. ABIN563635
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application IF, ELISA, WB
Validations
  • (2)
Cat. No. ABIN521912
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN7242053
Quantity 200 μL
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN6744352
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7148750
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Cullin 2 Antibodies

Meng, Chen, Han, Qian, Wang, Zhong, Qin, Zhang, Gao, Lei, Yang, Yang, Zhang, Liu, Liu, Zhou, Sun, Yang: "Twist1 Regulates Vimentin through Cul2 Circular RNA to Promote EMT in Hepatocellular Carcinoma." in: Cancer research, Vol. 78, Issue 15, pp. 4150-4162, (2018) (PubMed).

Argyropoulos, Stütz, Ilnytska, Rice, Teran-Garcia, Rao, Bouchard, Rankinen: "KIF5B gene sequence variation and response of cardiac stroke volume to regular exercise." in: Physiological genomics, Vol. 36, Issue 2, pp. 79-88, (2009) (PubMed).

Shiraishi, Zhou, Aoki, Sato, Chiba, Tanaka, Yoshida, Nabeshima, Nabeshima, Tamura: "TBP-interacting protein 120B (TIP120B)/cullin-associated and neddylation-dissociated 2 (CAND2) inhibits SCF-dependent ubiquitination of myogenin and accelerates myogenic differentiation." in: The Journal of biological chemistry, Vol. 282, Issue 12, pp. 9017-28, (2007) (PubMed).

Maine, Mao, Komarck, Burstein: "COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase." in: The EMBO journal, Vol. 26, Issue 2, pp. 436-47, (2007) (PubMed).

Saitoh, Pizzi, Wang: "Perturbation of SUMOlation enzyme Ubc9 by distinct domain within nucleoporin RanBP2/Nup358." in: The Journal of biological chemistry, Vol. 277, Issue 7, pp. 4755-63, (2002) (PubMed).

Feng, Zhong, Punkosdy, Gu, Zhou, Seabolt, Kipreos: "CUL-2 is required for the G1-to-S-phase transition and mitotic chromosome condensation in Caenorhabditis elegans." in: Nature cell biology, Vol. 1, Issue 8, pp. 486-92, (2000) (PubMed).

Clifford, Walsh, Hewson, Green, Brinke, Green, Gianelli, Eng, Maher et al.: "Genomic organization and chromosomal localization of the human CUL2 gene and the role of von Hippel-Lindau tumor suppressor-binding protein (CUL2 and VBP1) mutation and loss in renal-cell carcinoma ..." in: Genes, chromosomes & cancer, Vol. 26, Issue 1, pp. 20-8, (1999) (PubMed).

Michel, Xiong: "Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A." in: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, Vol. 9, Issue 6, pp. 435-49, (1998) (PubMed).

Pause, Lee, Worrell, Chen, Burgess, Linehan, Klausner: "The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 6, pp. 2156-61, (1997) (PubMed).

Kipreos, Lander, Wing, He, Hedgecock: "cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family." in: Cell, Vol. 85, Issue 6, pp. 829-39, (1996) (PubMed).

Aliases for Cullin 2 Antibodies

cullin 2 (cul2) Antibodies
cullin 2 (CUL2) Antibodies
cullin-2 (PTRG_05231) Antibodies
putative cullin-2 (cul-2) (Smp_079740) Antibodies
cullin-2 (LOC100550749) Antibodies
cullin 2 (Cul2) Antibodies
cullin 2 L homeolog (cul2.L) Antibodies
Cullin-2 (cul-2) Antibodies
1300003D18Rik Antibodies
4932411N15Rik Antibodies
AI327301 Antibodies
ATCUL2 Antibodies
cul2 Antibodies
Cullin-2 Antibodies
cullin-2 Antibodies
cullin 2 Antibodies
F22D16.2 Antibodies
F22D16_2 Antibodies
fj48a06 Antibodies
LOC100221330 Antibodies
mKIAA4106 Antibodies
wu:fj48a06 Antibodies
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