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anti-Gap Junction Protein, beta 2, 26kDa (GJB2) Antibodies

GJB2 encodes a member of the gap junction protein family. Additionally we are shipping GJB2 Kits (36) and GJB2 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GJB2 14619 Q00977
GJB2 394266 P21994
GJB2 2706 P29033
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Top anti-GJB2 Antibodies at antibodies-online.com

Showing 10 out of 91 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-GJB2 Antibody  Positive Control: Lane 1:41 µg mCx26 ... 100 μL Log in to see 2 to 3 Days
$229.00
Details
Mouse Goat Un-conjugated ELISA, WB ABIN190896 (0.01µg/ml) staining of Mouse Brain lysate (35µg protein in... 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with ... Western blot analysis of hGJB2-C218.Connexin (ABIN388370) in mouse bra... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated WB Anti-GJB2 antibody, Western blotting WB: Rat Liver Tissue Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Rat Mouse Un-conjugated IHC (fro), IHC (p), ELISA, WB Rat Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$595.83
Details
Mouse Mouse Un-conjugated IF, IHC (p), ELISA, WB Anti-GJB2 antibody IHC staining of human liver. Immunohistochemistry o... 50 μg Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated IF, WB Western blot analysis of Rat liver sections using Connexin 26 antibody 0.1 mg Log in to see 6 to 8 Days
$313.50
Details
Dog Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details

GJB2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Top referenced anti-GJB2 Antibodies

  1. Cow (Bovine) Polyclonal GJB2 Primary Antibody for WB - ABIN2774858 : Ulfig: Expression of connexin 26 in the ganglionic eminence of preterm infants after bleedings. in Neuroscience research 2004 (PubMed)

  2. Human Polyclonal GJB2 Primary Antibody for WB - ABIN374836 : Djalilian, McGaughey, Patel, Seo, Yang, Cheng, Tomic, Sinha, Ishida-Yamamoto, Segre: Connexin 26 regulates epidermal barrier and wound remodeling and promotes psoriasiform response. in The Journal of clinical investigation 2006 (PubMed)

More Antibodies against GJB2 Interaction Partners

Xenopus laevis Gap Junction Protein, beta 2, 26kDa (GJB2) interaction partners

  1. Using reconstituted hemichannels in a liposome-based transport-specific fractionation assay, we confirmed that homomeric Cx26 and Cx32 (show GJB1 Antibodies) and heteromeric Cx26/Cx32 (show GJB1 Antibodies) are permeable to GSH and other endogenous reductants.

Mouse (Murine) Gap Junction Protein, beta 2, 26kDa (GJB2) interaction partners

  1. presence of Cx30 (show GJB6 Antibodies) in the cochlea does not compensate for Cx26 loss, and the absence of both connexins from vestibular sensory epithelia is no more injurious than the absence of one of them

  2. Reciprocal positive regulation between Cx26 and PI3K/Akt (show AKT1 Antibodies) pathway confers acquired gefitinib resistance in non-small-cell lung carcinoma cells by promoting epithelial mesenchymal transition via a gap-junctional communication-independent manner.

  3. The inserting reconstituted gap junction Cx26 liposomes into the oocytes allowed the demonstration of intracellular/extracellular Ca(2 (show CA2 Antibodies)+)-regulated hemi-channel activities.

  4. Study used an inducible gene knockout technique to delete Cx26 expression in the cochlea after birth, results suggest that Cx26 deficiency may impair active cochlear amplification leading to late-onset hearing loss

  5. These results suggest that low levels of Cx26 expression throughout pregnancy and lactation, and not the physiological surge in Cx26, is sufficient for normal gland development and function.

  6. These results suggest that successful treatment of Cx26 deafness requires early intervention before the cochlea fully matures.

  7. Over-expression of BDNF (show BDNF Antibodies) beginning around 1 month of age resulted in a significant rescue of spiral ganglion degeneration in connexin 26 knockout mice.

  8. Using two models of CX26-associated deafness, we demonstrate that disruption of the CX26-dependent gap junction plaque is the earliest observable change during embryonic development of connexin-associated deafness.

  9. These data suggest that cell degeneration is not a primary causer of Cx26 deficiency associated hearing loss.

  10. Results indicated that connexin26 (Cx26) may play essential roles in the postnatal maturation of the cochlea, and its role in normal hearing at more mature stage may be replaceable.

Human Gap Junction Protein, beta 2, 26kDa (GJB2) interaction partners

  1. The detection rate of the single GJB2 mutation among the 160 SNHL subjects in the present study (6.25%) was higher than 2.58% in normal hearing controls in Korean. The DFNB1 was clearly excluded as a molecular etiology in four (40%) subjects

  2. We found a novel mutation in the GJB2 gene and two trimutations with SNHL not previously reported.

  3. ER-alpha (show ESR1 Antibodies) status of endometrioid adenocarcinomas could restrict eventual proapoptotic or anti-apoptotic impact of aberrantly expressed Cx43 (show GJA1 Antibodies) and Cx26 in these tumors.

  4. GJB2 mutation is associated with hereditary deafness in Yakutiya.

  5. GJB2 and SLC26A4 (show SLC26A4 Antibodies) mutations are associated with good post-implant outcomes.

  6. exon sequencing of GJB2, SLC26A4 (show SLC26A4 Antibodies), and mtDNA12SrRNA reveals that non-syndromic deafness in Xiamen, China appears to have a genetic etiology

  7. Data suggest that ombined hearing screening and genetic screening of gap junction protein beta 2 (GJB2), mtDNA 12srRNA and solute carrier (show SERTAD2 Antibodies) family 26, member 4 protein SLC26A4 (show SLC26A4 Antibodies) mutations can improve the rate of detection.

  8. Cx26 structure is nearly identical with and without bound Ca2 (show CA2 Antibodies)+. Ca2 (show CA2 Antibodies)+ regulates Cx26 via ionic conduction block via an electrostatic barrier rather than steric occlusion of the channel pore.

  9. Connexin26 mutation is responsible for palmoplantar keratoderma and deafness.

  10. the total allele frequencies of the two most frequent mutations, c.35delG and c.-23+1G>A, among mutated alleles were found to be around 59 and 15.7 %, respectively among Iranian deaf individuals

Cow (Bovine) Gap Junction Protein, beta 2, 26kDa (GJB2) interaction partners

  1. intermediate invasive status of bovine trophoblast is supported by the fact that trophoblast giant cells coexpress connexins (Cx)26, Cx32 (show GJB1 Antibodies), and Cx43 (show GJA1 Antibodies)

GJB2 Antigen Profile

Protein Summary

This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness.

Gene names and symbols associated with GJB2

  • gap junction protein, beta 2, 26kDa (gjb2) antibody
  • gap junction protein, beta 2, 26kDa (GJB2) antibody
  • gap junction protein, beta 2 (Gjb2) antibody
  • AI325222 antibody
  • Cnx26 antibody
  • connexin-26 antibody
  • CX26 antibody
  • CXN-26 antibody
  • DFNA3 antibody
  • DFNA3A antibody
  • DFNB1 antibody
  • DFNB1A antibody
  • Gjb-2 antibody
  • GJB2 antibody
  • HID antibody
  • KID antibody
  • MGC53062 antibody
  • NSRD1 antibody
  • PPK antibody

Protein level used designations for GJB2

gap junction protein, beta 2, 26kDa , connexin 26 , connexin 29 , gap junction membrane channel protein beta 6 , gap junction protein, beta 2, 26kDa (connexin 26) , connexin-26 , gap junction beta-2 protein , gap junction membrane channel protein beta 2 , gap junction channel protein connexin 26 , connexin26 , gap junction protein beta 2 , connexin 26 protein , cx26

GENE ID SPECIES
380170 Xenopus laevis
467220 Pan troglodytes
14619 Mus musculus
394266 Rattus norvegicus
100379528 Cavia porcellus
2706 Homo sapiens
403570 Canis lupus familiaris
407154 Bos taurus
443345 Ovis aries
704224 Macaca mulatta
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