Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
The protein encoded by HAVCR2 belongs to the immunoglobulin superfamily, and TIM family of proteins. Additionally we are shipping Hepatitis A Virus Cellular Receptor 2 Antibodies (155) and Hepatitis A Virus Cellular Receptor 2 Proteins (29) and many more products for this protein.
Showing 1 out of 6 products:
The Tim-3/Gal-9 (show LGALS9 ELISA Kits) pathway might link disease progression with T cell exhaustion during bovine leukemia virus infection.
The Gal-9 (show LGALS9 ELISA Kits)/Tim-3 signal is important for the regulation of decidua NK cells function, which is beneficial for the maintenance of a normal pregnancy.
These data indicate that Tim-3 expression in NK cells can function as a prognostic biomarker in human lung adenocarcinoma and support that Tim-3 could be a new target for an immunotherapeutic strategy.
Tim-3 in primary leukocytes, both healthy and malignant AML cells, displays moderate properties of an inflammatory receptor with additional growth factor (mTOR activation) and pro-angiogenic (VEGF release) activities
Tim-3 played an important role in the development and progression of gastric cancer, and it could be used as an independent prognostic factor for gastric cancer patients.
an abnormal Tim-3/Gal-9 (show LGALS9 ELISA Kits) pathway was able to facilitate the development of preeclampsia.
sTim-3 was involved in the development of sepsis. The homeostasis-promoting role of the Tim-3 on the monocytes was disrupted, while the inhibitory role of sTim-3 emerged during sepsis-induced immunosuppression.
decreased serum TIM-1 and TIM-3 levels and association of TIM-3 with nephritis suggest their possible role in the development and pathogenesis of systemic lupus erythematosus.
Results indicate that upregulation of the inhibitory receptor Tim-3 may restrict T cell responses in CRC (show CALR ELISA Kits) patients.
TIM-3 is a negative regulator of TCR-function by attenuating activation signals mediated by CD3 (show CD3 ELISA Kits)/CD28 (show CD28 ELISA Kits) co-stimulation.
Tim-3 might participate in the tumorgenesis of colon cancer and Tim-3 expression might be a potential independent prognostic factor for patients with colorectal cancer.
TIM-3 expression by NK cells and gamma/delta T cells is similar in the peripheral and decidual immune cells from pregnant mice.
Tim-3 acts at a receptor-proximal point to enhance Lyn (show LYN ELISA Kits) kinase-dependent signaling pathways that modulate both immediate-phase degranulation and late-phase cytokine production downstream of FcepsilonRI (show FCER1A ELISA Kits) ligation.
Our data indicate that Tim-3 expression on NK cells is regulated by T-bet, and that Tim-3 levels correlate with advanced stages of gastric cancer
TIM-3 plays a role in regulating the uterine natural killer cells and contributes to the maintenance of tolerance at the feto-maternal interface.
TIM-3 is highly expressed in hypoxic brain regions of a mouse cerebral hypoxia-ischaemia (H/I) model. TIM-3 is distinctively upregulated in activated microglia and astrocytes in a HIF-1 (show HIF1A ELISA Kits)-dependent manner.
These data identify an IL-27 (show IL27 ELISA Kits)/NFIL3 (show NFIL3 ELISA Kits) signalling axis as a key regulator of effector T-cell responses via induction of Tim-3, IL-10 (show IL10 ELISA Kits) and T-cell dysfunction.
CD4 (show CD4 ELISA Kits)+ T cell-dependent "negative" TIM-3 costimulation is essential for hepatic homeostasis and resistance against IR stress in OLTs
In DSS (show PMP22 ELISA Kits) colitis, Tim-3 inhibited the polarization of pathogenic pro-inflammatory M1 macrophages, while Tim-3 downregulation or blockade resulted in an increased M1 response. Tim-3 effect on macrophage response may be TLR4 (show TLR4 ELISA Kits) dependent.
These data suggest that Tim-3 and IFN-gamma (show IFNG ELISA Kits) may play a regulatory role in T. gondii-infected pregnant mouse model.
The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
hepatitis A virus cellular receptor 2
, T cell immunoglobulin mucin 3
, T cell immunoglobulin mucin-3
, T-cell immunoglobulin and mucin domain-containing protein 3
, T-cell membrane protein 3
, kidney injury molecule-3
, T-cell immunoglobulin and mucin domain containing 3
, hepatitis A virus cellular receptor 2 homolog