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anti-Integrin beta 3 (ITGB3) Antibodies

The ITGB3 protein product is the integrin beta chain beta 3. Additionally we are shipping Integrin beta 3 Kits (19) and Integrin beta 3 Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ITGB3 16416 O54890
ITGB3 29302  
ITGB3 3690 P05106
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Top anti-Integrin beta 3 Antibodies at

Showing 10 out of 652 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IHC (fro), IHC (p) Formalin fixed paraffin embedded human bone marrow stained with CD61 antibody ABIN114659 0.5 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated EIA, WB Western blot analysis of ITGB3 Antibody 0.4 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IF (cc), IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human rectal carcinoma labeled with Anti-Integrin beta 3/CD61 Polyclonal Antibody, Unconjugated (ABIN739029) at 1:200, followed by conjugation to the secondary antibody and DAB staining Mouse placenta lysates probed withAnti-Integrin beta 3 Polyclonal Antibody, Unconjugated  at 1:5000 90min in 37˚C 100 μL Log in to see 3 to 7 Days
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of ITGB3 Antibody (C-term) (ABIN652616) in CEM cell line lysates (35 µg/lane). ITGB3 (arrow) was detected using the purified polyclonal antibody.(2 µg/mL) Formalin-fixed and paraffin-embedded human testis tissue reacted with ITGB3 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
Human Mouse Un-conjugated EIA, IF, IHC (p), IP 0.1 mg Log in to see 6 to 8 Days
Mouse Hamster FITC FACS Staining of mouse peripheral blood platelets with HAMSTER ANTI MOUSE CD61:FITC 0.1 mg Log in to see 6 to 8 Days
Mouse Rat Un-conjugated FACS, IP, WB 0.1 mg Log in to see 6 to 8 Days
Cow Mouse FITC FACS 0.1 mg Log in to see 6 to 8 Days
Human Mouse Un-conjugated IF, WB Western blot analysis of Intergrin beta3 on a human platelet lysate. Lane 1: 1:2500, lane 2: 1:5000, lane 3: 1:10000 dilution of the anti- human CD61 antibody. 50 μg Log in to see 5 to 6 Days
Human Rabbit Un-conjugated EIA, IHC (p) 0.1 mg Log in to see 6 to 8 Days

ITGB3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Integrin beta 3 Antibodies

  1. Human Monoclonal Integrin beta 3 Primary Antibody for IF, WB - ABIN968389 : Chen, Djaffar, Pidard, Steiner, Cieutat, Caen, Rosa et al.: Ser-752-->Pro mutation in the cytoplasmic domain of integrin beta 3 subunit and defective activation of platelet integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) in a variant of Glanzmann ... in Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)
    Show all 5 references for ABIN968389

  2. Human Monoclonal Integrin beta 3 Primary Antibody for IHC (fro), IHC (p) - ABIN114660 : Kanz, Mielke, Fauser: Analysis of human hemopoietic progenitor cells for the expression of glycoprotein IIIa. in Experimental hematology 1988 (PubMed)
    Show all 4 references for ABIN114660

  3. Cow (Bovine) Monoclonal Integrin beta 3 Primary Antibody for FACS - ABIN317409 : Pérez de la Lastra, Moreno, Pérez, Llanes: Characterization of the porcine homologue to human platelet glycoprotein IIb-IIIa (CD41/CD61) by a monoclonal antibody. in Tissue antigens 1997 (PubMed)
    Show all 3 references for ABIN317409

  4. Human Monoclonal Integrin beta 3 Primary Antibody for EIA, IF - ABIN1106489 : Newton, Girgenti, Collier, Duman: Electroconvulsive seizure increases adult hippocampal angiogenesis in rats. in The European journal of neuroscience 2006 (PubMed)
    Show all 3 references for ABIN1106489

  5. Human Polyclonal Integrin beta 3 Primary Antibody for IF (cc), IF (p) - ABIN739029 : Wang, Jiang, Peng, Guo, Shang, Chen, Wu, Chen: Induced apoptosis of osteoblasts proliferating on polyhydroxyalkanoates. in Biomaterials 2013 (PubMed)
    Show all 3 references for ABIN739029

  6. Mouse (Murine) Monoclonal Integrin beta 3 Primary Antibody for FACS, IP - ABIN1449278 : Jonker, Schinkel: Pharmacological and physiological functions of the polyspecific organic cation transporters: OCT1, 2, and 3 (SLC22A1-3). in The Journal of pharmacology and experimental therapeutics 2004 (PubMed)
    Show all 2 references for ABIN1449278

  7. Human Polyclonal Integrin beta 3 Primary Antibody for EIA, WB - ABIN453710 : Wang, Furihata, McFarland, Friedman, Aster, Newman: An amino acid polymorphism within the RGD binding domain of platelet membrane glycoprotein IIIa is responsible for the formation of the Pena/Penb alloantigen system. in The Journal of clinical investigation 1992 (PubMed)

  8. Mouse (Murine) Monoclonal Integrin beta 3 Primary Antibody for FACS - ABIN120248 : Yasuda, Hasunuma, Adachi, Sekine, Sakanishi, Hashimoto, Ra, Yagita, Okumura: Expression and function of fibronectin binding integrins on rat mast cells. in International immunology 1995 (PubMed)

More Antibodies against Integrin beta 3 Interaction Partners

Mouse (Murine) Integrin beta 3 (ITGB3) interaction partners

  1. suppression of beta3-integrin in mice leads to the activation of a neuropilin-1 (NRP1 (show NRP1 Antibodies))-dependent cell migration pathway in endothelial cells via a mechanism that depends on NRP1 (show NRP1 Antibodies)'s mobilisation away from mature focal adhesions following VEGF (show VEGFA Antibodies)-stimulation

  2. Deletion of Itgb3 causes increased B-cell responses to TLR stimulation in vitro.

  3. integrin beta3-mediated signaling in smooth muscle cells links elastin (show ELN Antibodies) deficiency and pathological stenosis, and inhibiting this pathway is an attractive therapeutic strategy for supravalvular aortic stenosis.

  4. The clathrin-mediated endocytic machinery combines with Dab2 (show DAB2 Antibodies) to facilitate the endocytosis of RGD-integrin-beta3 clusters.

  5. Integrin beta 3 causes arteriovenous graft occlusion.

  6. Taken together, our results reveal that TD-26 is a novel antithrombotic compound exhibiting both integrin alphaIIbbeta3 inhibition and PI3K signaling blockage, with a low bleeding risk.

  7. Conformational activation of talin by PREL-1 (show APBB1IP Antibodies) triggers integrin-mediated cell adhesion.

  8. beta3/kindlin-2 (show FERMT2 Antibodies) interaction promotes outside-in alphaVbeta3 signaling selectively, with biological consequences in vivo

  9. alphaIIbbeta3 regulates Syk (show SYK Antibodies) through an ITAM-independent pathway in mice and provide novel insight into the course of events underlying Syk (show SYK Antibodies) activation and hemITAM phosphorylation by CLEC-2 (show CLEC1B Antibodies)

  10. Integrin alphav beta3/Dap12 (show TYROBP Antibodies) double-deficient developed profound osteoporosis.

Human Integrin beta 3 (ITGB3) interaction partners

  1. This study shows correlation of blood clot (show TXNDC17 Antibodies) stiffness with platelet integrin alpha-IIb (show ITGA2B Antibodies) beta3 activity, aspirin usage, and transfusion risk in cardiopulmonary bypass patients.

  2. T4, but not T3, controls integrin's outside-in signaling by phosphorylating tyrosine 759 in the beta3 subunit. ERK (show EPHB2 Antibodies)-mediated transcription regulation of the b3 monomer is regulated by T3 and T4which are alphavbeta3-ligands driving ovarian cancer cell proliferation .

  3. Our data provide evidence that ADAM23 (show Adam23 Antibodies) plays a role in suppression of cancer cell progression through interaction with aVb3 integrin, and suggest that downregulation of ADAM23 (show Adam23 Antibodies) in SP cells may contribute toward providing a cancer stem cell phenotype

  4. Data show that immune thrombocytopenia (ITP (show ITPA Antibodies)) is an autoimmune bleeding disorder characterized by low platelet count and presence of IgG autoantibodies to platelet surface glycoproteins, such as alpha IIbbeta3 integrins.

  5. Data suggest that the ligand AGDV tetrapeptide binds to ITGB3/GPIIIa subunit and induces complete opening of headpiece of integrin alphaIIb/beta3 complex; AGDV appears to have very little contact with ITGA2B/GPIIb (show ITGA2B Antibodies) subunit.

  6. CD61-overexpressing human umbilical cord mesenchymal stem cell, which had turned into primordial germ-like cells-like cells, could be further differentiated into male germ-like cells.

  7. The frequencies of the rare alleles of CCR2 (show CCR2 Antibodies), ITGB3, and 3'UTR (show UTS2R Antibodies) of c-fms (show CSF1R Antibodies) in the Old Believers are lower than in the sample of Novosibirsk Russians, and the rare allele of DBH (show DBH Antibodies) is more frequent

  8. Data suggest that reduced ability of AnxA6 (show ANXA6 Antibodies)-expressing cells to migrate is associated with decreased cell surface expression of integrins alphaVbeta3 and alpha5beta1.

  9. results demonstrate that beta3 integrin expression depends on the source of the fibroblast and that its expression inhibits alphaSMA (show ACTA2 Antibodies) expression (and thus the myofibroblast phenotype).

  10. 33Leu --> Pro substitution of GPIIIa does not influence the prevalence and extent of angiographically defined coronary artery disease in general population, although apparently playing a role among younger patients.

Pig (Porcine) Integrin beta 3 (ITGB3) interaction partners

  1. The observed effects of shear stress on integrin alpha(v (show ITGAV Antibodies))beta(3) and p38 MAPK (show MAPK14 Antibodies) activation, as well as on FGF-2 (show FGF2 Antibodies) release could be mimicked by application of pancreatic elastase to static endothelial cells.

  2. structure and distribution of the CD61 provides insight into the physiological function of the porcine beta(3) integrins and should be of importance in understanding the role of this integrin family in biological processes

  3. Inhibition of integrin alphavbeta3 (show ITGAV Antibodies) prevents urokinase plasminogen (show PLG Antibodies) activator-mediated impairment of cerebrovasodilation after cerebral hypoxia/ischemia.

Cow (Bovine) Integrin beta 3 (ITGB3) interaction partners

  1. alphavbeta3 integrin engagement in vascular endothelium regulates Ca2 (show CA2 Antibodies)+-dependent K+ current

  2. Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.

Integrin beta 3 (ITGB3) Antigen Profile

Protein Summary

The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.

Gene names and symbols associated with anti-Integrin beta 3 (ITGB3) Antibodies

  • integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) (ITGB3) antibody
  • integrin beta 3 (Itgb3) antibody
  • integrin, beta 3 (Itgb3) antibody
  • BDPLT2 antibody
  • BDPLT16 antibody
  • CD61 antibody
  • GP3A antibody
  • GPIIIA antibody
  • GT antibody
  • INGRB3 antibody
  • INTB3 antibody
  • integrin antibody

Protein level used designations for anti-Integrin beta 3 (ITGB3) Antibodies

integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) , integrin beta3 , GPIIIa , integrin beta-3 , platelet gpIIIa , platelet membrane glycoprotein IIIa , integrin beta 3 (Cd61) , beta3 integrin , glycoprotein GPIIIa , integrin beta 3 , integrin beta-3 subunit

100423047 Ovis aries
16416 Mus musculus
29302 Rattus norvegicus
3690 Homo sapiens
397063 Sus scrofa
282642 Bos taurus
374209 Gallus gallus
403788 Canis lupus familiaris
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