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The ITGB3 protein product is the integrin beta chain beta 3. Additionally we are shipping Integrin beta 3 Kits (21) and Integrin beta 3 Proteins (10) and many more products for this protein.
Showing 10 out of 697 products:
Human Monoclonal Integrin beta 3 Primary Antibody for IF, WB - ABIN968389
Chen, Djaffar, Pidard, Steiner, Cieutat, Caen, Rosa et al.: Ser-752-->Pro mutation in the cytoplasmic domain of integrin beta 3 subunit and defective activation of platelet integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) in a variant of Glanzmann ... in Proceedings of the National Academy of Sciences of the United States of America 1992
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Human Monoclonal Integrin beta 3 Primary Antibody for IHC (fro), IHC (p) - ABIN114660
Kanz, Mielke, Fauser: Analysis of human hemopoietic progenitor cells for the expression of glycoprotein IIIa. in Experimental hematology 1988
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Human Polyclonal Integrin beta 3 Primary Antibody for ELISA, IF (cc) - ABIN739029
Wang, Jiang, Peng, Guo, Shang, Chen, Wu, Chen: Induced apoptosis of osteoblasts proliferating on polyhydroxyalkanoates. in Biomaterials 2013
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Human Monoclonal Integrin beta 3 Primary Antibody for EIA, IF - ABIN1106489
Newton, Girgenti, Collier, Duman: Electroconvulsive seizure increases adult hippocampal angiogenesis in rats. in The European journal of neuroscience 2006
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Cow (Bovine) Monoclonal Integrin beta 3 Primary Antibody for FACS - ABIN317409
Pérez de la Lastra, Moreno, Pérez, Llanes: Characterization of the porcine homologue to human platelet glycoprotein IIb-IIIa (CD41/CD61) by a monoclonal antibody. in Tissue antigens 1997
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Mouse (Murine) Monoclonal Integrin beta 3 Primary Antibody for FACS, IP - ABIN1449278
Jonker, Schinkel: Pharmacological and physiological functions of the polyspecific organic cation transporters: OCT1, 2, and 3 (SLC22A1-3). in The Journal of pharmacology and experimental therapeutics 2004
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Human Monoclonal Integrin beta 3 Primary Antibody for FACS - ABIN4897102
Park-Min, Lee, Moskowitz, Lim, Lee, Lorenzo, Huang, Melnick, Purdue, Goldring, Ivashkiv: Negative regulation of osteoclast precursor differentiation by CD11b and β2 integrin-B-cell lymphoma 6 signaling. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2012
Mouse (Murine) Monoclonal Integrin beta 3 Primary Antibody for FACS - ABIN120248
Yasuda, Hasunuma, Adachi, Sekine, Sakanishi, Hashimoto, Ra, Yagita, Okumura: Expression and function of fibronectin binding integrins on rat mast cells. in International immunology 1995
Human Polyclonal Integrin beta 3 Primary Antibody for EIA, WB - ABIN453710
Wang, Furihata, McFarland, Friedman, Aster, Newman: An amino acid polymorphism within the RGD binding domain of platelet membrane glycoprotein IIIa is responsible for the formation of the Pena/Penb alloantigen system. in The Journal of clinical investigation 1992
By modulating its affinity with kindlin, beta3 integrin may be able to locate near the cell edge where it can control beta1 integrin activation and clustering.
MiR (show MLXIP Antibodies)-30a-5p suppresses tumor metastasis of human colorectal cancer by targeting ITGB3.
suppression of beta3-integrin in mice leads to the activation of a neuropilin-1 (NRP1 (show NRP1 Antibodies))-dependent cell migration pathway in endothelial cells via a mechanism that depends on NRP1 (show NRP1 Antibodies)'s mobilisation away from mature focal adhesions following VEGF (show VEGFA Antibodies)-stimulation
Deletion of Itgb3 causes increased B-cell responses to TLR stimulation in vitro.
integrin beta3-mediated signaling in smooth muscle cells links elastin (show ELN Antibodies) deficiency and pathological stenosis, and inhibiting this pathway is an attractive therapeutic strategy for supravalvular aortic stenosis.
The clathrin-mediated endocytic machinery combines with Dab2 (show DAB2 Antibodies) to facilitate the endocytosis of RGD-integrin-beta3 clusters.
Integrin beta 3 causes arteriovenous graft occlusion.
Taken together, our results reveal that TD-26 is a novel antithrombotic compound exhibiting both integrin alphaIIbbeta3 inhibition and PI3K signaling blockage, with a low bleeding risk.
Conformational activation of talin by PREL-1 (show APBB1IP Antibodies) triggers integrin-mediated cell adhesion.
beta3/kindlin-2 (show FERMT2 Antibodies) interaction promotes outside-in alphaVbeta3 signaling selectively, with biological consequences in vivo
Suggest that ERK1/2 (show MAPK1/3 Antibodies) plays an important role in mediating non-canonical TGFbeta (show TGFB1 Antibodies) signal pathways for integrin beta3 expression in mesenchymal tumor cells.
Thirteen variants in the ITGA2B (show ITGA2B Antibodies) locus and 29 variants in the ITGB3 locus were identified.
GPIIIa polymorphism was not associated with poor responsiveness to clopidogrel in coronary heart disease patients of Han ethnicity.
endothelial VEGFR-2 appeared to be slightly superior to endothelial alpha v ss 3 for differentiating benign from cancerous lesions.
PDI-mediated disulfide bond exchange plays a pivotal role in the post-ligation phase of alphaIIbbeta3-mediated adhesion to fibrinogen, while this step in alphavbeta3-mediated adhesion is independent of disulfide exchange
Our results indicate that GpIa (show ITGA2 Antibodies)-807T and GpIIIa-PlA2 (show YWHAZ Antibodies) may be susceptibility alleles for in vitro fertilization implantation failure.
Identify integrin alphavbeta3 (show ITGAV Antibodies) as a receptor ofNC1 domain of collagen XIX. NC1(XIX) inhibits the FAK (show PTK2 Antibodies)/PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies) pathway, by decreasing the phosphorylation and activity of the major proteins involved in this pathway.
beta3 integrin downregulation by miR (show MLXIP Antibodies)-30a-5p modulates cell adhesion and invasion by interrupting Erk (show EPHB2 Antibodies)/Ets1 (show ETS1 Antibodies) network in triple-negative breast cancer
Data show that integrin beta3 and serine/threonine-protein kinase LKB1 (show STK11 Antibodies) are involved in the inhibition of proliferation by lovastatin independently.
The observed effects of shear stress on integrin alpha(v (show ITGAV Antibodies))beta(3) and p38 MAPK (show MAPK14 Antibodies) activation, as well as on FGF-2 (show FGF2 Antibodies) release could be mimicked by application of pancreatic elastase to static endothelial cells.
structure and distribution of the CD61 provides insight into the physiological function of the porcine beta(3) integrins and should be of importance in understanding the role of this integrin family in biological processes
Inhibition of integrin alphavbeta3 (show ITGAV Antibodies) prevents urokinase plasminogen (show PLG Antibodies) activator-mediated impairment of cerebrovasodilation after cerebral hypoxia/ischemia.
alphavbeta3 integrin engagement in vascular endothelium regulates Ca2 (show CA2 Antibodies)+-dependent K+ current
Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.
The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
, integrin beta3
, integrin beta-3
, platelet gpIIIa
, platelet membrane glycoprotein IIIa
, integrin beta 3 (Cd61)
, beta3 integrin
, glycoprotein GPIIIa
, integrin beta 3
, integrin beta-3 subunit