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The ITGB3 protein product is the integrin beta chain beta 3. Additionally we are shipping Integrin beta 3 Kits (19) and Integrin beta 3 Proteins (10) and many more products for this protein.
Showing 10 out of 526 products:
Human Monoclonal Integrin beta 3 Primary Antibody for IF, WB - ABIN968389
Chen, Djaffar, Pidard, Steiner, Cieutat, Caen, Rosa et al.: Ser-752-->Pro mutation in the cytoplasmic domain of integrin beta 3 subunit and defective activation of platelet integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) in a variant of Glanzmann ... in Proceedings of the National Academy of Sciences of the United States of America 1992
Show all 5 references for ABIN968389
Human Monoclonal Integrin beta 3 Primary Antibody for IHC (fro), IHC (p) - ABIN114660
Kanz, Mielke, Fauser: Analysis of human hemopoietic progenitor cells for the expression of glycoprotein IIIa. in Experimental hematology 1988
Show all 4 references for ABIN114660
Cow (Bovine) Monoclonal Integrin beta 3 Primary Antibody for FACS - ABIN317409
Pérez de la Lastra, Moreno, Pérez, Llanes: Characterization of the porcine homologue to human platelet glycoprotein IIb-IIIa (CD41/CD61) by a monoclonal antibody. in Tissue antigens 1997
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Human Monoclonal Integrin beta 3 Primary Antibody for EIA, IF - ABIN1106489
Newton, Girgenti, Collier, Duman: Electroconvulsive seizure increases adult hippocampal angiogenesis in rats. in The European journal of neuroscience 2006
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Human Polyclonal Integrin beta 3 Primary Antibody for IF (cc), IF (p) - ABIN739029
Wang, Jiang, Peng, Guo, Shang, Chen, Wu, Chen: Induced apoptosis of osteoblasts proliferating on polyhydroxyalkanoates. in Biomaterials 2013
Show all 3 references for ABIN739029
Mouse (Murine) Monoclonal Integrin beta 3 Primary Antibody for FACS, IP - ABIN1449278
Jonker, Schinkel: Pharmacological and physiological functions of the polyspecific organic cation transporters: OCT1, 2, and 3 (SLC22A1-3). in The Journal of pharmacology and experimental therapeutics 2004
Show all 2 references for ABIN1449278
Human Polyclonal Integrin beta 3 Primary Antibody for EIA, WB - ABIN453710
Wang, Furihata, McFarland, Friedman, Aster, Newman: An amino acid polymorphism within the RGD binding domain of platelet membrane glycoprotein IIIa is responsible for the formation of the Pena/Penb alloantigen system. in The Journal of clinical investigation 1992
Mouse (Murine) Monoclonal Integrin beta 3 Primary Antibody for FACS - ABIN120248
Yasuda, Hasunuma, Adachi, Sekine, Sakanishi, Hashimoto, Ra, Yagita, Okumura: Expression and function of fibronectin binding integrins on rat mast cells. in International immunology 1995
suppression of beta3-integrin in mice leads to the activation of a neuropilin-1 (NRP1 (show NRP1 Antibodies))-dependent cell migration pathway in endothelial cells via a mechanism that depends on NRP1 (show NRP1 Antibodies)'s mobilisation away from mature focal adhesions following VEGF (show VEGFA Antibodies)-stimulation
Deletion of Itgb3 causes increased B-cell responses to TLR stimulation in vitro.
integrin beta3-mediated signaling in smooth muscle cells links elastin (show ELN Antibodies) deficiency and pathological stenosis, and inhibiting this pathway is an attractive therapeutic strategy for supravalvular aortic stenosis.
The clathrin-mediated endocytic machinery combines with Dab2 (show DAB2 Antibodies) to facilitate the endocytosis of RGD-integrin-beta3 clusters.
Integrin beta 3 causes arteriovenous graft occlusion.
Taken together, our results reveal that TD-26 is a novel antithrombotic compound exhibiting both integrin alphaIIbbeta3 inhibition and PI3K signaling blockage, with a low bleeding risk.
Conformational activation of talin by PREL-1 (show APBB1IP Antibodies) triggers integrin-mediated cell adhesion.
beta3/kindlin-2 (show FERMT2 Antibodies) interaction promotes outside-in alphaVbeta3 signaling selectively, with biological consequences in vivo
alphaIIbbeta3 regulates Syk (show SYK Antibodies) through an ITAM-independent pathway in mice and provide novel insight into the course of events underlying Syk (show SYK Antibodies) activation and hemITAM phosphorylation by CLEC-2 (show CLEC1B Antibodies)
Integrin alphav beta3/Dap12 (show TYROBP Antibodies) double-deficient developed profound osteoporosis.
T4, but not T3, controls integrin's outside-in signaling by phosphorylating tyrosine 759 in the beta3 subunit. ERK (show EPHB2 Antibodies)-mediated transcription regulation of the b3 monomer is regulated by T3 and T4which are alphavbeta3-ligands driving ovarian cancer cell proliferation .
Our data provide evidence that ADAM23 (show Adam23 Antibodies) plays a role in suppression of cancer cell progression through interaction with aVb3 integrin, and suggest that downregulation of ADAM23 (show Adam23 Antibodies) in SP cells may contribute toward providing a cancer stem cell phenotype
Data show that immune thrombocytopenia (ITP (show ITPA Antibodies)) is an autoimmune bleeding disorder characterized by low platelet count and presence of IgG autoantibodies to platelet surface glycoproteins, such as alpha IIbbeta3 integrins.
Data suggest that the ligand AGDV tetrapeptide binds to ITGB3/GPIIIa subunit and induces complete opening of headpiece of integrin alphaIIb/beta3 complex; AGDV appears to have very little contact with ITGA2B/GPIIb (show ITGA2B Antibodies) subunit.
CD61-overexpressing human umbilical cord mesenchymal stem cell, which had turned into primordial germ-like cells-like cells, could be further differentiated into male germ-like cells.
The frequencies of the rare alleles of CCR2 (show CCR2 Antibodies), ITGB3, and 3'UTR (show UTS2R Antibodies) of c-fms (show CSF1R Antibodies) in the Old Believers are lower than in the sample of Novosibirsk Russians, and the rare allele of DBH (show DBH Antibodies) is more frequent
Data suggest that reduced ability of AnxA6 (show ANXA6 Antibodies)-expressing cells to migrate is associated with decreased cell surface expression of integrins alphaVbeta3 and alpha5beta1.
results demonstrate that beta3 integrin expression depends on the source of the fibroblast and that its expression inhibits alphaSMA (show ACTA2 Antibodies) expression (and thus the myofibroblast phenotype).
33Leu --> Pro substitution of GPIIIa does not influence the prevalence and extent of angiographically defined coronary artery disease in general population, although apparently playing a role among younger patients.
ITGB3 expression increased with matrix rigidity. Blocking Ibeta3 reduced Gli2 (show GLI2 Antibodies) and PTHrP (show PTHLH Antibodies) expression. Ibeta3 co-localized with TGF-beta (show TGFB1 Antibodies) RII on rigid but not compliant films.
The observed effects of shear stress on integrin alpha(v (show ITGAV Antibodies))beta(3) and p38 MAPK (show MAPK14 Antibodies) activation, as well as on FGF-2 (show FGF2 Antibodies) release could be mimicked by application of pancreatic elastase to static endothelial cells.
structure and distribution of the CD61 provides insight into the physiological function of the porcine beta(3) integrins and should be of importance in understanding the role of this integrin family in biological processes
Inhibition of integrin alphavbeta3 (show ITGAV Antibodies) prevents urokinase plasminogen (show PLG Antibodies) activator-mediated impairment of cerebrovasodilation after cerebral hypoxia/ischemia.
alphavbeta3 integrin engagement in vascular endothelium regulates Ca2 (show CA2 Antibodies)+-dependent K+ current
Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.
The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
, integrin beta3
, integrin beta-3
, platelet gpIIIa
, platelet membrane glycoprotein IIIa
, integrin beta 3 (Cd61)
, beta3 integrin
, glycoprotein GPIIIa
, integrin beta 3
, integrin beta-3 subunit