Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

INSIG1 Antibodies

(Insulin Induced Gene 1 (INSIG1))
Oxysterols regulate cholesterol homeostasis through the liver X receptor (LXR)- and sterol regulatory element-binding protein (SREBP)-mediated signaling pathways. This gene is an insulin-induced gene. It encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. This protein binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jun 2009].
anti-Insulin Induced Gene 1 (INSIG1) (Middle Region) antibody anti-Insulin Induced Gene 1 (INSIG1) (Middle Region) antibody anti-Insulin Induced Gene 1 (INSIG1) (Middle Region) antibody (ABIN2778634)

INSIG1 Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish (Danio rerio) IHC, WB Host: Rabbit Polyclonal unconjugated

anti-Insulin Induced Gene 1 (INSIG1) (Internal Region) antibody anti-Insulin Induced Gene 1 (INSIG1) (Internal Region) antibody anti-Insulin Induced Gene 1 (INSIG1) (Internal Region) antibody (ABIN6262599)

INSIG1 Reactivity: Human, Mouse ICC, IF, IHC, WB Host: Rabbit Polyclonal unconjugated

anti-Insulin Induced Gene 1 (INSIG1) (AA 36-63), (N-Term) antibody anti-Insulin Induced Gene 1 (INSIG1) (AA 36-63), (N-Term) antibody anti-Insulin Induced Gene 1 (INSIG1) (AA 36-63), (N-Term) antibody (ABIN652887)

INSIG1 Reactivity: Human FACS, IHC (p), WB Host: Rabbit Polyclonal RB21689 unconjugated

INSIG1 Antibodies by Reactivity

Find INSIG1 Antibodies for a variety of species such as anti-Human INSIG1, anti-Mouse INSIG1, anti-Rat INSIG1. The species listed below are among those available. Click on a link to go to the corresponding products.

INSIG1 Antibodies by Application

Find INSIG1 Antibodies validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

INSIG1 Antibodies by Host

Find INSIG1 Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

INSIG1 Antibodies by Binding Specificity

Find INSIG1 Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

INSIG1 Antibodies by Clonality

Find available monoclonal or polyclonal INSIG1 Antibodies. Click on a link to go to the corresponding products.

INSIG1 Antibodies by Clone

Find INSIG1 Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

INSIG1 Antibodies by Conjugate

Find INSIG1 Antibodies with a specific conjugate such as FITC, APC, Alkaline Phosphatase (AP). The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular INSIG1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet

Application WB
Validations
  • (2)
Cat. No. ABIN2778638
Quantity 100 μL
Datasheet Datasheet

Application IHC, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN6748581
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN635167
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN635059
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN2778636
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN2458475
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application ICC, IF, WB
Validations
  • (1)
Cat. No. ABIN363575
Quantity 0.1 mL
Datasheet Datasheet
Reactivity Human, Monkey
Application WB
Validations
  • (1)
Cat. No. ABIN6740652
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Goat, Hamster, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep, Xenopus laevis
Application WB
Validations
  • (1)
Cat. No. ABIN6740654
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Hamster, Human, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN961031
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, IHC, WB
Validations
Cat. No. ABIN7156348
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7156349
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN7156350
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7156351
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC, WB
Validations
Cat. No. ABIN7115274
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our INSIG1 Antibodies

Yu, Zhao, Lai, Chu, Hao, Feng, Zhang, Liu, Cheng, Li, Shen, Min: "LncRNA as ceRNAs may be involved in lactation process." in: Oncotarget, Vol. 8, Issue 58, pp. 98014-98028, (2017) (PubMed).

Segatto, Di Giovanni, Marino, Pallottini: "Analysis of the protein network of cholesterol homeostasis in different brain regions: an age and sex dependent perspective." in: Journal of cellular physiology, Vol. 228, Issue 7, pp. 1561-7, (2013) (PubMed).

Segatto, Trapani, Lecis, Pallottini: "Regulation of cholesterol biosynthetic pathway in different regions of the rat central nervous system." in: Acta physiologica (Oxford, England), Vol. 206, Issue 1, pp. 62-71, (2012) (PubMed).

Trapani, Segatto, Simeoni, Balducci, Dhawan, Parmar, Prasad, Saso, Incerpi, Pallottini: "Short- and long-term regulation of 3-hydroxy 3-methylglutaryl coenzyme A reductase by a 4-methylcoumarin." in: Biochimie, Vol. 93, Issue 7, pp. 1165-71, (2011) (PubMed).

De Marinis, Martini, Trentalance, Pallottini: "Sex differences in hepatic regulation of cholesterol homeostasis." in: The Journal of endocrinology, Vol. 198, Issue 3, pp. 635-43, (2008) (PubMed).

Roth, Looser, Kaufmann, Blättler, Rencurel, Huang, Moore, Meyer: "Regulatory cross-talk between drug metabolism and lipid homeostasis: constitutive androstane receptor and pregnane X receptor increase Insig-1 expression." in: Molecular pharmacology, Vol. 73, Issue 4, pp. 1282-9, (2008) (PubMed).

Gong, Lee, Lee, Goldstein, Brown, Ye: "Sterol-regulated ubiquitination and degradation of Insig-1 creates a convergent mechanism for feedback control of cholesterol synthesis and uptake." in: Cell metabolism, Vol. 3, Issue 1, pp. 15-24, (2006) (PubMed).

Engelking, Liang, Hammer, Takaishi, Kuriyama, Evers, Li, Horton, Goldstein, Brown: "Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins." in: The Journal of clinical investigation, Vol. 115, Issue 9, pp. 2489-98, (2005) (PubMed).

Aliases for INSIG1 Antibodies

insulin induced gene 1 (INSIG1) Antibodies
insulin induced gene 1 (insig1) Antibodies
insulin induced gene 1 L homeolog (insig1.L) Antibodies
insulin induced gene 1 (Insig1) Antibodies
1810013C12Rik Antibodies
cl-6 Antibodies
CL-6 Antibodies
cl6 Antibodies
CL6 Antibodies
fb55a03 Antibodies
fi35b10 Antibodies
Insig-1 Antibodies
INSIG-1 Antibodies
wu:fb55a03 Antibodies
wu:fi35b10 Antibodies
zgc:55439 Antibodies
You are here:
Support