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Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. Additionally we are shipping Laminin gamma 1 Proteins (13) and Laminin gamma 1 Kits (8) and many more products for this protein.
Showing 10 out of 123 products:
Human Monoclonal Laminin gamma 1 Primary Antibody for ELISA, WB - ABIN396825
Johnatty, Beesley, Chen, Macgregor, Duffy, Spurdle, deFazio, Gava, Webb, Rossing, Doherty, Goodman, Lurie, Thompson, Wilkens, Ness, Moysich, Chang-Claude, Wang-Gohrke, Cramer, Terry, Hankinson, Tworoger, Garcia-Closas, Yang, Lissowska, Chanock, Pharoah, S: Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot". in PLoS genetics 2010
Show all 5 references for ABIN396825
Human Monoclonal Laminin gamma 1 Primary Antibody for IF, IHC (p) - ABIN180491
Ljubimov, Bartek, Couchman, Kapuller, Veselov, Kovarik, Perevoshchikov, Krutovskikh: Distribution of individual components of basement membrane in human colon polyps and adenocarcinomas as revealed by monoclonal antibodies. in International journal of cancer. Journal international du cancer 1992
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Mouse (Murine) Polyclonal Laminin gamma 1 Primary Antibody for IHC (fro), IHC (p) - ABIN191500
Kunze, Abari, Semkova, Paulsson, Hartmann: Deposition of nidogens and other basement membrane proteins in the young and aging mouse retina. in Ophthalmic research 2010
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Guinea Pig Monoclonal Laminin gamma 1 Primary Antibody for IHC (p) - ABIN180492
Sanes, Engvall, Butkowski, Hunter: Molecular heterogeneity of basal laminae: isoforms of laminin and collagen IV at the neuromuscular junction and elsewhere. in The Journal of cell biology 1990
Show all 2 references for ABIN180492
Human Polyclonal Laminin gamma 1 Primary Antibody for IHC, IHC (p) - ABIN4330132
Stadler, Hjelmare, Neumann, Jonasson, Pepperkok, Uhlén, Lundberg: Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy. in Journal of proteomics 2012
Human Polyclonal Laminin gamma 1 Primary Antibody for IHC, IHC (p) - ABIN4330131
Kuhn, Kurman, Soslow, Han, Sehdev, Morin, Wang, Shih: The diagnostic and biological implications of laminin expression in serous tubal intraepithelial carcinoma. in The American journal of surgical pathology 2012
Human Monoclonal Laminin gamma 1 Primary Antibody for EIA, IHC (fro) - ABIN1108021
Geberhiwot, Wondimu, Salo, Pikkarainen, Kortesmaa, Tryggvason, Virtanen, Patarroyo: Chain specificity assignment of monoclonal antibodies to human laminins by using recombinant laminin beta1 and gamma1 chains. in Matrix biology : journal of the International Society for Matrix Biology 2000
Human Polyclonal Laminin gamma 1 Primary Antibody for WB - ABIN2787604
Jakobsson, Domogatskaya, Tryggvason, Edgar, Claesson-Welsh: Laminin deposition is dispensable for vasculogenesis but regulates blood vessel diameter independent of flow. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008
Analysis of nidogen-1 (show NID1 Antibodies) and laminin-gamma1 interaction reveals multiple binding modes.
The C-terminal domains of mouse laminin gamma 1 and nidogen 1 (show NID1 Antibodies) mediate interactions complex formation.
STI1 (show STIP1 Antibodies) and Ln-gamma1 promote robust axonogenesis in wild-type neurons, whereas no effect is observed in neurons from PrPC (show PRNP Antibodies)-null mice.
Data show that expression of either mGluR1 (show GRM1 Antibodies) or mGluR5 (show GRM5 Antibodies) in HEK293 cells reconstituted the signaling pathways mediated by PrP(C (show PRNP Antibodies))-Ln gamma1 peptide interaction.
Laminin beta(1 (show LAMB1 Antibodies)) and gamma(1) N-terminal domains share the galactose-binding domain-like fold.
Basement membrane deposition of nidogen 1 but not nidogen 2 requires the nidogen binding module of the laminin gamma1 chain.
structure of the interacting domains reveals a six-bladed Tyr (show TYR Antibodies)-Trp (show TYRP1 Antibodies)-Thr (show TRH Antibodies)-Asp (show C3 Antibodies) (YWTD) beta-propeller domain in nidogen bound to laminin epidermal-growth-factor (show EGF Antibodies)-like (LE) modules III3-5 in laminin (LE3-5)
This study demonstrates (1) that laminin initiates axonal sorting and mediates axon-Schwann cell interactions required for Schwann cell proliferation and differentiation. (2) that laminin provides a PI3-kinase (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies)-mediated Schwann cell survival signal.
netrin-4 (show NTN4 Antibodies) is a component of basement membranes and is integrated into the laminin polymer via interactions with the laminin gamma1 andgamma3 short arms
The role of the laminin gamma1 chain for cardiac muscle differentiation and function using cardiomyocytes derived from embryonic stem cells deficient in the LAMC1 gene, was investigated.
Two zebrafish loci, grumpy (show LAMB1 Antibodies) and sleepy, encode laminin beta1 and laminin gamma1, respectively. These genes are required for the formation of the laminin-dependent basement membrane is essential for the differentiation of chordamesoderm to notochord.
Our results show that miR (show MLXIP Antibodies)-181a is down-regulated in glioblastoma multiforme (GBM) patients. The three target genes, ANGPT2 (show ANGPT2 Antibodies), ARHGAP18 (show ARHGAP18 Antibodies) and LAMC1, are negatively correlated with the expression of miR (show MLXIP Antibodies)-181a. Moreover, high expression of ANGPT2 (show ANGPT2 Antibodies) or LAMC1 together with large size of GBM is correlated with a shorter median overall survival
miR (show MLXIP Antibodies)-506 acts as a tumor suppressor and inhibits malignancy of colorectal cancer cells through directly targeting LAMC1.
Case Report: Anti-laminin-gamma 1 pemphigoid in patient with generalized pustular psoriasis and psoriasis vulgaris.
The identification of laminin gamma 1 (LAMC1) and myeloid cell leukemia 1 (MCL1 (show MCL1 Antibodies)) as direct targets of miR (show MLXIP Antibodies)-22 and miR (show MLXIP Antibodies)-29a, respectively, suggested a tumor-suppressive role of these miRNAs.
LAMC1 may contribute to the development and progression of uterine carcinoma, likely through enhancing tumor cell motility and invasion.
Case Report: occurrence of anti-laminin-gamma1 pemphigoid in a case of autosomal recessive congenital ichthyosis (show LBR Antibodies).
Laminins 411 and 421 differentially promote tumor cell migration via alpha6beta1 integrin and MCAM (CD146 (show MCAM Antibodies)).
Data showed that LAMC1 expression is directly regulated by miR (show MLXIP Antibodies)-29s.
carbohydrate moiety (alpha-Gal) on laminin gamma-1 and collagen alpha-1 (VI) chain are possibly common IgE-reactive proteins in the Japanese patients with beef allergy
results demonstrate that mutation in either NID1 (show NID1 Antibodies) or LAMC1 disrupts the interaction NID1 (show NID1 Antibodies)-LAMC1 complex; findings implicate the extracellular matrix in the pathogenesis of Dandy-Walker spectrum disorders
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins, composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively), have a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the gamma chain isoform laminin, gamma 1. The gamma 1 chain, formerly thought to be a beta chain, contains structural domains similar to beta chains, however, lacks the short alpha region separating domains I and II. The structural organization of this gene also suggested that it had diverged considerably from the beta chain genes. Embryos of transgenic mice in which both alleles of the gamma 1 chain gene were inactivated by homologous recombination, lacked basement membranes, indicating that laminin, gamma 1 chain is necessary for laminin heterotrimer assembly. It has been inferred by analogy with the strikingly similar 3' UTR sequence in mouse laminin gamma 1 cDNA, that multiple polyadenylation sites are utilized in human to generate the 2 different sized mRNAs (5.5 and 7.5 kb) seen on Northern analysis.
laminin gamma-1 chain
, laminin subunit gamma-1
, S-LAM gamma
, S-laminin subunit gamma
, laminin B2 chain
, laminin-1 subunit gamma
, laminin-10 subunit gamma
, laminin-11 subunit gamma
, laminin-2 subunit gamma
, laminin-3 subunit gamma
, laminin-4 subunit gamma
, laminin-6 subunit gamma
, laminin-7 subunit gamma
, laminin-8 subunit gamma
, laminin-9 subunit gamma