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anti-MGC22014 (MGC22014) Antibodies

Members of the ten-eleven translocation (TET) gene family, including TET3, play a role in the DNA methylation process (Langemeijer et al., 2009 [PubMed 19923888]).[supplied by OMIM, Nov 2010]..

list all antibodies Gene Name GeneID UniProt
MGC22014 200424 O43151
MGC22014    
MGC22014    
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Top anti-MGC22014 Antibodies at antibodies-online.com

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Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IF, WB Western blot analysis of TET3 in SK-N-SH cell lysate with TET3 Antibody  at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide 0.1 mg Log in to see 6 to 8 Days
$401.50
Details

MGC22014 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human


Mouse (Murine)


Rat (Rattus)


Top referenced anti-MGC22014 Antibodies

  1. Human Polyclonal MGC22014 Primary Antibody for EIA, IF - ABIN1449990 : Langemeijer, Kuiper, Berends, Knops, Aslanyan, Massop, Stevens-Linders, van Hoogen, van Kessel, Raymakers, Kamping, Verhoef, Verburgh, Hagemeijer, Vandenberghe, de Witte, van der Reijden, Jansen: Acquired mutations in TET2 are common in myelodysplastic syndromes. in Nature genetics 2009 (PubMed)
    Show all 3 references for ABIN1449990

More Antibodies against MGC22014 Interaction Partners

Human MGC22014 interaction partners

  1. We found that TET1 (show TET1 Antibodies) and TET2 (show TET2 Antibodies) messenger RNA expression was lower and TET3 (show TET3 Antibodies) was higher in cancers compared to normal tissues. Positive correlation between 5-hmC and the relative expression of TET1 (show TET1 Antibodies) and TET2 (show TET2 Antibodies) was found, but no correlation was observed in the case of TET3 (show TET3 Antibodies).

  2. TET1 (show TET1 Antibodies), TET2 (show TET2 Antibodies), and TET3 (show TET3 Antibodies) genes are downregulated in endometriosis.

  3. Results revealed that TET3 (show TET3 Antibodies) acted as a suppressor of ovarian cancer by demethylating miR (show MLXIP Antibodies)-30d precursor gene promoter to block TGF-beta1 (show TGFB1 Antibodies)-induced epithelial-mesenchymal transition.

  4. TET3 (show TET3 Antibodies) expression inhibits glioblastoma tumorigenesis and self-renewal in glioblastoma stem cells.

  5. levels of TET3 (show TET3 Antibodies) and TDG (show TDG Antibodies) mRNAs were independent prognostic factors for early breast cancer patients who received anthracycline chemotherapy

  6. Hypoxia deregulates TET3 (show TET3 Antibodies). TET1 (show TET1 Antibodies)/3 levels were associated with tumor hypoxia, tumor malignancy, and poor prognosis in breast cancer patients. Coordinate functions of TET1 (show TET1 Antibodies) and TET3 (show TET3 Antibodies) were needed to activate TNFalpha (show TNF Antibodies)-p38-MAPK (show MAPK14 Antibodies) signaling in hypoxia.

  7. In hepatic stellate cells, cell proliferation rise significantly and cell apoptosis reduce obviously after knockdown of TET3 (show TET3 Antibodies).

  8. GABRA3 (show GABRA3 Antibodies) also carries a microRNA (miR (show MLXIP Antibodies)-767) with predicted target sites in TET1 (show TET1 Antibodies) and TET3 (show TET3 Antibodies), two members of the ten-eleven-translocation family of tumor suppressor genes, involved in the conversion of 5-methylcytosines to 5-hydroxymethylcytosines in DNA.

  9. TET1 (show TET1 Antibodies), TET2 (show TET2 Antibodies), and TET3 (show TET3 Antibodies) are highly phosphorylated.

  10. TET1 (show TET1 Antibodies) depletion yields widespread reduction of 5hmC, while depletion of TET2 (show TET2 Antibodies) and TET3 (show TET3 Antibodies) reduces 5hmC at a subset of TET1 (show TET1 Antibodies) targets suggesting functional co-dependence.

MGC22014 Antigen Profile

Protein Summary

Members of the ten-eleven translocation (TET) gene family, including TET3, play a role in the DNA methylation process (Langemeijer et al., 2009

Gene names and symbols associated with anti-MGC22014 (MGC22014) Antibodies

  • tet methylcytosine dioxygenase 3 (TET3) antibody

Protein level used designations for anti-MGC22014 (MGC22014) Antibodies

methylcytosine dioxygenase TET3 , probable methylcytosine dioxygenase TET3 , tet oncogene family member 3

GENE ID SPECIES
200424 Homo sapiens
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