TET3 antibody (AA 1159-1329)

Catalog No. ABIN2668513

Product Details anti-TET3 Antibody

Target: TET3 (Tet Methylcytosine Dioxygenase 3 (TET3))

Binding Specificity: AA 1159-1329

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TET3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: None

Immunogen: This antibody was raised against a recombinant protein corresponding to amino acids 1159-1329 of mouse Tet3.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit serum containing 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage: -20 °C

Storage Comment: Antibodies in solution can be stored at -20 °C for 2 years.

Expiry Date: 6 months

References for anti-TET3 antibody (ABIN2668513)

Thienpont, Steinbacher, Zhao, DAnna, Kuchnio, Ploumakis, Ghesquière, Van Dyck, Boeckx, Schoonjans, Hermans, Amant, Kristensen, Koh, Mazzone, Coleman, Carell, Carmeliet, Lambrechts: "Tumour hypoxia causes DNA hypermethylation by reducing TET activity." in: Nature, Vol. 537, Issue 7618, pp. 63-68, (2016) (PubMed).

Otani, Kimura, Sharif, Endo, Mishima, Kawakami, Koseki, Shirakawa, Suetake, Tajima: "Cell cycle-dependent turnover of 5-hydroxymethyl cytosine in mouse embryonic stem cells." in: PLoS ONE, Vol. 8, Issue 12, pp. e82961, (2013) (PubMed).

Target Details for TET3

Target: TET3 (Tet Methylcytosine Dioxygenase 3 (TET3))

Alternative Name: Tet3 (TET3 Products)

Molecular Weight: 200 kDa

Gene ID: 194388

Pathways: Warburg Effect