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The product of MOG is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Additionally we are shipping MOG Antibodies (120) and MOG Proteins (35) and many more products for this protein.
Showing 9 out of 33 products:
Mouse (Murine) MOG ELISA Kit - ABIN1882535
Hatterer, Touret, Belin, Honnorat, Nataf: Cerebrospinal fluid dendritic cells infiltrate the brain parenchyma and target the cervical lymph nodes under neuroinflammatory conditions. in PLoS ONE 2008
Identify nerve growth factor as a binding partner for MOG and demonstrate that this interaction is capable of sequestering NGF (show NGFB ELISA Kits) from TrkA (show NTRK1 ELISA Kits)-expressing neurons to modulate axon growth and survival.
Data indicate that in mixed chimeras with bone marrow-encoding myelin oligodendrocyte glycoprotein (MOG), the development of MOG-specific B cells was abrogated, resulting in a lack of MOG-specific B cells in all B cell compartments examined.
Identify immunogenic/encephalitogenic T-cell epitopes within MOG capable of inducing experimental autoimmune encephalomyelitis in C57BL/6 mice.
PLP (show C3 ELISA Kits) significantly suppresses both models of experimental autoimmune encephalitis (EAE)even when there is some evidence of epitope spreading in the myelin oligodendrocyte (MOG)38-50-induced EAE model.
CNTF (show CNTF ELISA Kits) may play a role in the process of remyelination by inducing the MOG expression.
MOG-specific CD4 (show CD4 ELISA Kits)-positive T cells accumulate within the chemokine (show CCL1 ELISA Kits)-expressing draining lymph nodes, rather than within the brain or spinal cord during induction of autoimmune encephalomyelitis.
This study provides valuable information about requirements of anti-myelin oligodendrocyte glycoprotein reactivity for being regarded as a prognostic biomarker in a subtype of MS.
Mice immunized with encephalitogenic myelin oligodendrocyte glycoprotein MOG(35-55) peptide develop significant serum levels of anti-MOG antibodies in parallel with disease progression.
B cell-deficient mice exhibit reduced medullary thymic epithelial cell numbers and reduced MOG mRNA expression.
Cell surface targeting of MOG is not disrupted in the absence of the endoplasmic reticulum chaperones.
MOG antibody associated optic neuritis tends to involve the anterior optic pathway.
This study demonstrated that increased expression of mRNA of OLIG1 (show OLIG1 ELISA Kits) in ventral prefrontal white matter in major depressive disorder.
In patients with idiopathic optic neuritis, 27.6% (8/29) were positive for MOG antibodies. Three of the eight MOG-positive patients showed significantly high CSF (show CSF2 ELISA Kits) levels of myelin basic protein (show MBP ELISA Kits). Five had optic pain and three had prodromal infection.
Immune modulation by a tolerogenic myelin oligodendrocyte glycoprotein (MOG)10-60 containing fusion protein in the marmoset experimental autoimmune encephalomyelitis model.
These data demonstrate a new role for myelin glycosylation in the control of immune homeostasis in the healthy human brain through the MOG-DC-SIGN (show CD209 ELISA Kits) homeostatic regulatory axis, which is comprised by inflammatory insults that affect glycosylation.
findings suggest that immune reactions toward MOG and in particular MOG-specific antibodies may play a functional role in multiple sclerosis
Patients with neuromyelitis optica spectrum disorders with MOG antibodies have distinct clinical features, fewer attacks, and better recovery than patients with AQP4 (show AQP4 ELISA Kits) antibodies or patients seronegative for both antibodies.
Bipolar I disorder and schizophrenia share a number of common genetic risk loci and susceptibility genes including the genes coding for myelin oligodendrocytes glycoprotein (MOG).
We could show for the first time that a subset of aquaporin 4 (show AQP4 ELISA Kits)-IgG seronegative patients with neuromyelitis optica exhibit a MOG-IgG mediated immune response
The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.
myelin oligodendrocyte glycoprotein
, Myelin-oligodendrocyte glycoprotein
, myelin-oligodendrocyte glycoprotein-like
, MOG alpha-7Cj
, myelin-oligodendrocyte glycoprotein
, MOG Ig-AluB
, MOG alpha-5
, dystonia 2, torsion (autosomal recessive)
, myelin-oligodendrocyte glycoprotein isoform beta1