Netrin 4 Proteins (NTN4)

NTN4 belongs to a family of proteins related to laminins (see LAMA1, MIM 150320) Koch et al. Additionally we are shipping Netrin 4 Antibodies (59) and Netrin 4 Kits (18) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NTN4 59277 Q9HB63
NTN4 57764 Q9JI33
Rat NTN4 NTN4 299737  
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Top Netrin 4 Proteins at

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
HOST_Escherichia coli (E. coli) Human His tag,GST tag 100 μg Log in to see 15 to 18 Days

NTN4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
Mouse (Murine)

More Proteins for Netrin 4 (NTN4) Interaction Partners

Zebrafish Netrin 4 (NTN4) interaction partners

  1. the crucial role of Netrin-4 in blood vessel formation and the involvement of protein kinases activation in Netrin-4-induced biological effects related to vascular development.

  2. netrin 4 is detected only at very low levels during early development

Human Netrin 4 (NTN4) interaction partners

  1. NTN4 is reduced in breast cancer tissues and NTN4 is associated with breast cancer cell migration and invasion via regulation of epithelial mesenchymal transition (EMT (show ITK Proteins))-related biomarkers.

  2. We found statistically significant association with AAO for three genes (WRN, NTN4 and LAMC3 (show LAMC3 Proteins)) with common associated variants.

  3. Ntn4 promotes the proliferation and motility of gastric cancer cells which is mediated by its receptor Neo and through further activation of multi-oncogenic pathways

  4. Increased expression of miR (show MLXIP Proteins)-20a may play an important role in the pathogenesis of ovarian endometriosis by suppressing NTN4 expression.

  5. Increased maternal netrin-4 levels in IUGR neonates may reflect in utero hypoxia, while the negative correlations between fetal netrin-1 (show NTN1 Proteins) and -4 levels may exert the dynamic balance between their angio- and anti-angiogenic properties.

  6. NTN4 acts as a positive regulator for TC axon branching through activity-dependent expression

  7. NETRIN-4 protects glioblastoma cells FROM temozolomide induced senescence.

  8. NTN4 expression was downregulated in cervical cancer tissues compared to normal controls, and in vivo mRNA level of NTN4 inversely correlated with miR (show MLXIP Proteins)-196a expression.

  9. GWAS study found two new SNPs associated with nickel dermatitis; SNPs are located in the NTN4 and PELI1 (show PELI1 Proteins) genes

  10. pattern of distribution suggests that a functional netrin-4-neogenin (show NEO1 Proteins) pathway might be restricted to syncytiotrophoblasts, mesenchymal cells, and villous endothelial cells

Mouse (Murine) Netrin 4 (NTN4) interaction partners

  1. Netrin-4 acted as an antiangiogenic factor in the cornea, with which the healthy cornea is enriched via its expression by corneal epithelial cells.

  2. Our results indicate a role for netrin-4 as an angiogenesis modulating factor in O2-dependent vascular homeostasis while being less important during normal retinal developmental angiogenesis or during inflammatory neovascularization.

  3. These results indicate that netrin-4 shed new light on its potential roles in treatmenting for angiogenic diseases that affect the ocular surface, as well as other tissues

  4. Vascular endothelial cells interact with bone in suppressing bone through netrin-4.

  5. Loss of Netrin-4 is associated with metastatic colorectal tumor progression.

  6. The alpha6beta1 integrin is a netrin-4 receptor in endothelial cells.

  7. NT-4 (show NTF4 Proteins) overexpression decreases tumor growth and carcinomatosis, probably via an antiangiogenic effect

  8. In vivo, Netrin-4 induces growth of lymphatic and blood vessels in the skin of transgenic mice.

  9. netrin-4 is a component of basement membranes and is integrated into the laminin polymer via interactions with the laminin gamma1 andgamma3 short arms.

  10. Netrin-4 significantly reduced pathological angiogenesis in Matrigel and laser-induced choroidal neovascularization models. Netrin-4, neogenin (show NEO1 Proteins), and Unc5B (show UNC5B Proteins) receptor expression was up-regulated in choroidal neovessel EC after laser injury

Netrin 4 (NTN4) Protein Profile

Protein Summary

NTN4 belongs to a family of proteins related to laminins (see LAMA1, MIM 150320) Koch et al. (2000)

Gene names and symbols associated with Netrin 4 Proteins (NTN4)

  • netrin-4-like (LOC100065441)
  • netrin 4 (NTN4)
  • netrin 4 (ntn4)
  • netrin 4 (Ntn4)
  • netrin-4-like (LOC100516554)
  • Netrin-4 protein
  • PRO3091 protein
  • RGD1565947 protein

Protein level used designations for Netrin 4 Proteins (NTN4)

netrin 4 , netrin-4 , netrin4 , netrin-4-like , beta-netrin , hepar-derived netrin-like protein

100065441 Equus caballus
467098 Pan troglodytes
561440 Danio rerio
712628 Macaca mulatta
780511 Ovis aries
100172474 Pongo abelii
100329096 Saccoglossus kowalevskii
100379839 Xenopus (Silurana) tropicalis
100410845 Callithrix jacchus
100541214 Meleagris gallopavo
100582122 Nomascus leucogenys
59277 Homo sapiens
57764 Mus musculus
475431 Canis lupus familiaris
537455 Bos taurus
299737 Rattus norvegicus
417914 Gallus gallus
100516554 Sus scrofa
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