The protein encoded by this gene is a glycoprotein containing several von Willebrand factor C domains and epidermal growth factor (EGF)-like domains. The encoded protein acts as a homotrimer and is found in the cytoplasm. Several variants encoding a few different isoforms exist, and at least one isoform appears to be a secreted protein. Studies in mouse suggest that this protein plays a role in neural cell growth and differentiation as well as in oncogenesis. [provided by RefSeq, Feb 2009].
Kim, Kim, An, Kang, Park, Hwang, Seo, Jang, Ha, Lee: "NELL2 Function in Axon Development of Hippocampal Neurons." in: Molecules and cells, Vol. 43, Issue 6, pp. 581-589, (2020) (PubMed).
Aliases for NELL2 Proteins
neural EGFL like 2 L homeolog (nell2.L) Proteins NEL-like 2 (Nell2) Proteins neural EGFL like 2 (NELL2) Proteins neural EGFL like 2 (Nell2) Proteins neural EGFL like 2a (nell2a) Proteins A330108N19Rik Proteins mel91 Proteins nel Proteins nell2 Proteins NRP2 Proteins R75516 Proteins wu:fj43h11 Proteins zgc:158375 Proteins