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neonatal Fc Receptor Proteins

(neonatal Fc Receptor (FcRn))
This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009].

Active filters:

  • Target: FcRn
  • Protein
Catalog no. Product Reactivity Host / Clonality Application Price & lead time
ABIN7274677
FcRn Protein (AA 22-297) (His tag) FcRn · Protein Mouse HEK-293 Cells
  • SDS (SDS-PAGE: Validation image available)
  • SPR (Surface Plasmon Resonance: Validation image available)
  • SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: Validation image available)
$456.18 View price
  • 100 μg
  • 500 μg
Delivery in 3 to 6 Business Days Shipping to: United States
ABIN7274675
FcRn Protein (AA 24-297) (His tag) FcRn · Protein Cynomolgus, Rhesus Monkey HEK-293 Cells
  • SDS (SDS-PAGE: Validation image available)
  • SPR (Surface Plasmon Resonance: Validation image available)
  • ELISA (ELISA: Validation image available)
  • SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: Validation image available)
$445.92 View price
  • 100 μg
  • 500 μg
Delivery in 3 to 6 Business Days Shipping to: United States
ABIN7274676
FcRn Protein (AA 24-297) (His tag) FcRn · Protein Human HEK-293 Cells
  • SDS (SDS-PAGE: Validation image available)
  • SPR (Surface Plasmon Resonance: Validation image available)
  • SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: Validation image available)
  • ELISA (ELISA: Validation image available)
$456.18 View price
  • 100 μg
  • 500 μg
Delivery in 3 to 6 Business Days Shipping to: United States
ABIN7536880
FcRn Protein (AA 24-297) (His-Avi Tag,Biotin) FcRn · Protein Human HEK-293 Cells
  • SDS (SDS-PAGE: Validation image available)
  • SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: Validation image available)
  • SPR (Surface Plasmon Resonance: Validation image available)
$1,083.08 View price
  • 250 μg
  • 5 x 250 μg
Delivery in 7 to 10 Business Days Shipping to: United States
ABIN7536879
FcRn Protein (AA 24-297) (His-Avi Tag) FcRn · Protein Human HEK-293 Cells
  • SDS (SDS-PAGE: Validation image available)
  • SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: Validation image available)
  • SPR (Surface Plasmon Resonance: Validation image available)
$1,083.08 View price
  • 1 mg
  • 5 x 1 mg
Delivery in 7 to 10 Business Days Shipping to: United States
ABIN1353903
FcRn Protein (AA 51-160) (GST tag) FcRn · Protein Human Wheat germ
  • AP (Affinity Purification: Listed application)
  • AA (Antibody Array: Listed application)
  • ELISA (ELISA: Listed application)
  • WB (Western Blotting: Listed application)
$447.26 View price
  • 10 μg
  • 25 μg
Delivery in 11 to 14 Business Days Shipping to: United States
ABIN5854760
FcRn Protein (AA 22-297) (His tag) FcRn · Protein Mouse Baculovirus infected Insect Cells
  • SDS (SDS-PAGE: Validation image available)
$676.92 View price
  • 50 μg
  • 10 μg
  • 250 μg
Delivery in 13 to 18 Business Days Shipping to: United States
ABIN2870741
FcRn Protein (AA 22-297) (His tag,Strep Tag) FcRn · Protein Mouse HEK-293 Cells
  • SDS (SDS-PAGE: Validation image available)
  • ELISA (ELISA: Validation image available)
$495.08 View price
  • 50 μg
  • 1 mg
  • 100 μg
Delivery in 2 to 4 Business Days Shipping to: United States
ABIN2870550
FcRn Protein (AA 24-297) (His tag,Strep Tag,AVI tag,Biotin) FcRn · Protein Human HEK-293 Cells
  • SDS (SDS-PAGE: Validation image available)
  • Bind (Binding Studies: Validation image available)
$1,465.38 View price
  • 200 μg
  • 25 μg
Delivery in 2 to 4 Business Days Shipping to: United States
ABIN2181081
FcRn Protein (AA 24-297) (His tag,Strep Tag) FcRn · Protein Cynomolgus, Rhesus Monkey HEK-293 Cells
  • SDS (SDS-PAGE: Validation image available)
  • Bind (Binding Studies: Validation image available)
$495.08 View price
  • 50 μg
  • 1 mg
  • 100 μg
Delivery in 2 to 4 Business Days Shipping to: United States
ABIN2181085
FcRn Protein (AA 24-297) (His tag,Strep Tag) FcRn · Protein Human HEK-293 Cells
  • SDS (SDS-PAGE: Validation image available)
  • Bind (Binding Studies: Validation image available)
$495.08 View price
  • 50 μg
  • 1 mg
  • 100 μg
Delivery in 2 to 4 Business Days Shipping to: United States
ABIN7580616
FcRn Protein (His tag) FcRn · Protein Mouse Escherichia coli (E. coli)
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
$345.09 View price
  • 100 μg
Delivery in 12 to 15 Business Days Shipping to: United States
ABIN7678672
FcRn Protein (AA 22-301) (His tag) FcRn · Protein Mouse Mammalian Cells
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • ELISA (ELISA: Listed application)
  • AcA (Activity Assay: Listed application)
$535.66 View price
  • 100 μg
  • 50 μg
Delivery in 12 to 15 Business Days Shipping to: United States
ABIN2115488
FcRn Protein (AA 21-119, AA 24-290) (His tag) FcRn · Protein Human Human Cells
$475.80 View price
  • 50 μg
  • 1 mg
  • 10 μg
  • 500 μg
Delivery in 4 to 5 Business Days Shipping to: United States
ABIN7889635
FcRn Protein (AA 21-119, AA 22-297) (His tag) FcRn · Protein Mouse HEK-293 Cells
$184.74 View price
  • 10 μg
Delivery in 4 to 5 Business Days Shipping to: United States
ABIN7889636
FcRn Protein (AA 21-119, AA 24-297, Heterodimer) (His tag) FcRn · Protein Human Human Cells
$220.55 View price
  • 10 μg
Delivery in 4 to 5 Business Days Shipping to: United States
ABIN7889637
FcRn Protein (AA 21-119, AA 24-297) (His-Avi Tag,Biotin) FcRn · Protein Human Human Cells
$1,035.98 View price
  • 100 μg
Delivery in 4 to 5 Business Days Shipping to: United States
ABIN7534672
FcRn Protein FcRn · Protein Human HEK-293 Cells
$533.50 View price
  • 100 μg
  • 1 mg
  • 10 μg
  • 20 μg
  • 50 μg
  • 500 μg
Delivery in 7 to 10 Business Days Shipping to: United States
ABIN7583297
FcRn Protein (AA 23-298) (His tag) FcRn · Protein Rat HEK-293 Cells
$456.18 View price
  • 100 μg
  • 500 μg
Delivery in 3 to 6 Business Days Shipping to: United States
ABIN7504325
FcRn Protein (AA 22-297) (Biotin,His-Avi Tag) FcRn · Protein Mouse HEK-293 Cells
$715.42 View price
  • 100 μg
  • 500 μg
Delivery in 3 to 6 Business Days Shipping to: United States
Protein
  • SDS (SDS-PAGE: Validation image available)
  • SPR (Surface Plasmon Resonance: Validation image available)
  • SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: Validation image available)
Origin
Mouse
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
Biological Activity
Active
Catalog No. ABIN7274677
$456.18
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 3 to 6 Business Days
Protein
  • SDS (SDS-PAGE: Validation image available)
  • SPR (Surface Plasmon Resonance: Validation image available)
  • ELISA (ELISA: Validation image available)
  • SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: Validation image available)
Origin
Cynomolgus, Rhesus Monkey
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
Biological Activity
Active
Catalog No. ABIN7274675
$445.92
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 3 to 6 Business Days
Protein
  • SDS (SDS-PAGE: Validation image available)
  • SPR (Surface Plasmon Resonance: Validation image available)
  • SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: Validation image available)
  • ELISA (ELISA: Validation image available)
Origin
Human
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
Biological Activity
Active
Catalog No. ABIN7274676
$456.18
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 3 to 6 Business Days
Protein
  • SDS (SDS-PAGE: Validation image available)
  • SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: Validation image available)
  • SPR (Surface Plasmon Resonance: Validation image available)
Origin
Human
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 95 % by SEC-HPLC
Catalog No. ABIN7536880
$1,083.08
Plus shipping costs $50.00
250 μg (More quantities available)
Shipping to: United States
Delivery in 7 to 10 Business Days
Protein
  • SDS (SDS-PAGE: Validation image available)
  • SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: Validation image available)
  • SPR (Surface Plasmon Resonance: Validation image available)
Origin
Human
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 95 % by SEC-HPLC
Catalog No. ABIN7536879
$1,083.08
Plus shipping costs $50.00
1 mg (More quantities available)
Shipping to: United States
Delivery in 7 to 10 Business Days
Protein
  • AP (Affinity Purification: Listed application)
  • AA (Antibody Array: Listed application)
  • ELISA (ELISA: Listed application)
  • WB (Western Blotting: Listed application)
Origin
Human
Host
Wheat germ
Protein Type
Recombinant
Catalog No. ABIN1353903
$447.26
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 14 Business Days
Protein
  • SDS (SDS-PAGE: Validation image available)
Origin
Mouse
Host
Baculovirus infected Insect Cells
Protein Type
Recombinant
Purity
> 85 %
Catalog No. ABIN5854760
$676.92
Plus shipping costs $50.00, if applicable $20.00 dry ice
50 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 18 Business Days
Protein
  • SDS (SDS-PAGE: Validation image available)
  • ELISA (ELISA: Validation image available)
Origin
Mouse
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
>95 % as determined by SDS-PAGE.
Catalog No. ABIN2870741
$495.08
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 2 to 4 Business Days
Protein
  • SDS (SDS-PAGE: Validation image available)
  • Bind (Binding Studies: Validation image available)
Origin
Human
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
>95 % as determined by SDS-PAGE.
Biological Activity
Active
Catalog No. ABIN2870550
$1,465.38
Plus shipping costs $50.00
200 μg (More quantities available)
Shipping to: United States
Delivery in 2 to 4 Business Days
Protein
  • SDS (SDS-PAGE: Validation image available)
  • Bind (Binding Studies: Validation image available)
Origin
Cynomolgus, Rhesus Monkey
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
>95 % as determined by SDS-PAGE.
Biological Activity
Active
Catalog No. ABIN2181081
$495.08
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 2 to 4 Business Days
Protein
  • SDS (SDS-PAGE: Validation image available)
  • Bind (Binding Studies: Validation image available)
Origin
Human
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
>95 % as determined by SDS-PAGE.
Biological Activity
Active
Catalog No. ABIN2181085
$495.08
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 2 to 4 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
Origin
Mouse
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Catalog No. ABIN7580616
$345.09
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 12 to 15 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • ELISA (ELISA: Listed application)
  • AcA (Activity Assay: Listed application)
Origin
Mouse
Host
Mammalian Cells
Protein Type
Recombinant
Purity
>90 % as determined by SDS-PAGE.
Biological Activity
Active
Catalog No. ABIN7678672
$535.66
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 12 to 15 Business Days
Protein
Origin
Human
Host
Human Cells
Protein Type
Recombinant
Purity
> 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN2115488
$475.80
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 4 to 5 Business Days
Protein
Origin
Mouse
Host
HEK-293 Cells
Protein Type
Recombinant
Catalog No. ABIN7889635
$184.74
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 5 Business Days
Protein
Origin
Human
Host
Human Cells
Protein Type
Recombinant
Catalog No. ABIN7889636
$220.55
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 5 Business Days
Protein
Origin
Human
Host
Human Cells
Protein Type
Recombinant
Catalog No. ABIN7889637
$1,035.98
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 4 to 5 Business Days
Protein
Origin
Human
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 97 % by SDS-PAGE.
Biological Activity
Active
Catalog No. ABIN7534672
$533.50
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 7 to 10 Business Days
Protein
Origin
Rat
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
Biological Activity
Active
Catalog No. ABIN7583297
$456.18
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 3 to 6 Business Days
Protein
Origin
Mouse
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
Biological Activity
Active
Catalog No. ABIN7504325
$715.42
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 3 to 6 Business Days

Latest Publications for our neonatal Fc Receptor Proteins

Spencer, Goldberg, Pandey, Ordonez, Dufloo, Barnette, Sutton, Henderson, Agnor, Gao, Bruel, Schwartz, Haigwood, Ackerman, Hessell: "Phagocytosis by an HIV antibody is associated with reduced viremia irrespective of enhanced complement lysis." in: Nature communications, Vol. 13, Issue 1, pp. 662, (2022) (PubMed).

Kisalu, Pereira, Ernste, Flores-Garcia, Idris, Asokan, Dillon, MacDonald, Shi, Chen, Pegu, Schön, Zavala, Balazs, Francica, Seder: "Enhancing durability of CIS43 monoclonal antibody by Fc mutation or AAV delivery for malaria prevention." in: JCI insight, Vol. 6, Issue 3, (2021) (PubMed).

Asokan, Dias, Liu, Maximova, Ernste, Pegu, McKee, Shi, Chen, Almasri, Promsote, Ambrozak, Gama, Hu, Douek, Todd, Lifson, Fourati, Sekaly, Crowley, Ackerman, Ko, Kilam, Boritz, Liao, Best, Perelson et al.: "Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, Issue 31, pp. 18754-18763, (2020) (PubMed).

Zhao, Gao, Yu, Li, Zhang, Zhang, Lu, Gao, Guo: "Unidirectional transport of IgG by neonatal Fc receptor in human thyrocytes varies across different IgG subclasses." in: Molecular and cellular endocrinology, Vol. 477, pp. 103-111, (2019) (PubMed).

Simonov, Ivanov, Smolov, Abbasova, Piskunov, Poteryaev: "Control of therapeutic IgG antibodies galactosylation during cultivation process and its impact on IgG1/FcγR interaction and ADCC activity." in: Biologicals : journal of the International Association of Biological Standardization, Vol. 58, pp. 16-21, (2019) (PubMed).

Yang, Kim, Seong, Tae, Kwon: "Comparative studies of the serum half-life extension of a protein via site-specific conjugation to a species-matched or -mismatched albumin." in: Biomaterials science, Vol. 6, Issue 8, pp. 2092-2100, (2018) (PubMed).

Kenniston, Taylor, Conley, Cosic, Kopacz, Lindberg, Comeau, Atkins, Bullen, TenHoor, Adelman, Sexton, Edwards, Nixon: "Structural basis for pH-insensitive inhibition of immunoglobulin G recycling by an anti-neonatal Fc receptor antibody." in: The Journal of biological chemistry, Vol. 292, Issue 42, pp. 17449-17460, (2017) (PubMed).

Zhou, Wang, Tong, Okamoto, Shen, Zaro: "Single chain Fc-dimer-human growth hormone fusion protein for improved drug delivery." in: Biomaterials, Vol. 117, pp. 24-31, (2017) (PubMed).

Fan, Neubert: "Quantitative Analysis of Human Neonatal Fc Receptor (FcRn) Tissue Expression in Transgenic Mice by Online Peptide Immuno-Affinity LC-HRMS." in: Analytical chemistry, Vol. 88, Issue 8, pp. 4239-47, (2016) (PubMed).

Deissler, Lang, Lang: "Internalization of bevacizumab by retinal endothelial cells and its intracellular fate: Evidence for an involvement of the neonatal Fc receptor." in: Experimental eye research, Vol. 143, pp. 49-59, (2015) (PubMed).

Aliases for neonatal Fc Receptor Proteins

Fc fragment of IgG receptor and transporter (FCGRT) Proteins
Fc fragment of IgG receptor and transporter (Fcgrt) Proteins
Fc receptor, IgG, alpha chain transporter (Fcgrt) Proteins
alpha-chain Proteins
FCRN Proteins
FcRn Proteins
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