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anti-OMA1 Zinc Metallopeptidase Homolog (S. Cerevisiae) (OMA1) Antibodies

Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Additionally we are shipping OMA1 Kits (3) and OMA1 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
OMA1 298282 D3ZS74
OMA1 67013 Q9D8H7
OMA1 115209 Q96E52
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Top anti-OMA1 Antibodies at

Showing 7 out of 8 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-OMA1 Antibody Titration: 0.2-1 ug/mlPositive Control: 721_B cell lysate Sample Type: HepG2 cellsPrimary Dilution: 1:1000Secondary Antibody: anti-Rabbit TBST with 5% BSASecondary Dilution: 1:5000Image Submitted by: Hana SabicUniversity of Utah 100 μL Log in to see 2 to 3 Days
Fish Rabbit Un-conjugated WB Western Blot: OMA1 Antibody [NBP1-56970] - Sample Type: HepG2 cells Primary Dilution: 1:1000 Secondary Antibody: anti-Rabbit TBST with 5% BSA Secondary Dilution: 1:5000 Image Submitted by: Hana Sabic University of Utah. Western Blot: OMA1 Antibody [NBP1-56970] - Lanes: Lane 1 : 10ug human fibroblast mitochondria. Lane 2: 15ug fish embryo lysate ; 6h post fertilization. Lane 3: 30ug fish embryo lysate , 6 days Primary, Antibody Dilution: 1 : 1000 Secondary Antibody: Anti-Rabbit HRP Secondary, Antibody Dilution: 1 : 5000 Gene name: OMA1. 50 μg Log in to see 16 to 18 Days
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: OMA1 Antibody [NBP2-30971] - Staining of human cell line U-251 MG shows positivity in mitochondria & nucleus but excluded from the nucleoli. Western Blot: OMA1 Antibody [NBP2-30971] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10 Lane 2: Human Tonsil tissue 0.1 mL Log in to see 8 to 11 Days
Human Rabbit Un-conjugated WB OMA1 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
Human Rabbit Un-conjugated ELISA, WB   50 μL Log in to see 9 to 11 Days
Human Rabbit Un-conjugated ELISA, WB   50 μL Log in to see 3 to 4 Days

OMA1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Rat (Rattus)

Mouse (Murine)


Top referenced anti-OMA1 Antibodies

  1. Fish Polyclonal OMA1 Primary Antibody for WB - ABIN4891256 : Desmurs, Foti, Raemy, Vaz, Martinou, Bairoch, Lane: C11orf83, a mitochondrial cardiolipin-binding protein involved in bc1 complex assembly and supercomplex stabilization. in Molecular and cellular biology 2015 (PubMed)
    Show all 2 references for ABIN4891256

More Antibodies against OMA1 Interaction Partners

Mouse (Murine) OMA1 Zinc Metallopeptidase Homolog (S. Cerevisiae) (OMA1) interaction partners

  1. stress-induced OMA1 activation and guanosine triphosphatase OPA1 (show MED12 Antibodies) cleavage limit mitochondrial fusion and promote neuronal death

  2. The IMQC protease Oma1 is required for the stability of the respiratory supercomplexes and thus balanced and tunable bioenergetic function.

  3. OMA1-mediated OPA1 (show MED12 Antibodies) proteolysis plays an important role in the disruption of mitochondrial dynamics in ischemic acute kidney injury.

  4. Constitutive OPA1 (show MED12 Antibodies) cleavage by YME1L (show YME1L1 Antibodies) and OMA1 at two distinct sites leads to the accumulation of both long and short forms of OPA1 (show MED12 Antibodies) and maintains mitochondrial fusion.

  5. Stress-induced OMA1 activation and autocatalytic turnover regulate OPA1 (show MED12 Antibodies)-dependent mitochondrial dynamics.

  6. This study shows that OMA1 plays an essential role in the proteolytic inactivation of the dynamin (show DNM1 Antibodies)-related GTPase (show RACGAP1 Antibodies) OPA1 (show MED12 Antibodies) and describes its unexpected role in energy metabolism

  7. OMA1 regulates OPA1 (show MED12 Antibodies) cleavage in the mitochondrial inner membrane.

Human OMA1 Zinc Metallopeptidase Homolog (S. Cerevisiae) (OMA1) interaction partners

  1. differential stress-induced degradation of YME1L (show YME1L1 Antibodies) and OMA1 as a mechanism for sensitively adapting mitochondrial inner membrane protease activity and function in response to distinct types of cellular insults.

  2. The mitochondrial metalloprotease (show ADAM8 Antibodies) OMA1 was activated in a Bax (show BAX Antibodies)- and Bak (show BAK1 Antibodies)-dependent fashion.

  3. Cleavage of the inner membrane fusion factor L-OPA1 (show OPA1 Antibodies) is prevented due to the failure to activate the inner membrane protease OMA1 in mitochondria that have a collapsed membrane potential.

  4. OMA1 is cleaved to a short form (S-OMA1) by itself upon mitochondrial membrane depolarization; S-OMA1 is degraded quickly but could be stabilized by CCCP treatment or Prohibitin (show PHB Antibodies) knockdown in cells.

  5. These findings demonstrate that (a) p53 (show TP53 Antibodies) and Oma1 mediate L-Opa1 (show OPA1 Antibodies) processing, (b) mitochondrial fragmentation is involved in CDDP-induced apoptosis in OVCA and CECA cells, and (c) dysregulated mitochondrial dynamics

  6. OMA1 controls OPA1 (show OPA1 Antibodies) cleavage and function.

  7. These results provide evidence for different substrate specificities of m-AAA (show APP Antibodies) proteases composed of different subunits and reveal a striking evolutionary switch of proteases involved in the proteolytic processing of dynamin (show DNM1 Antibodies)-like GTPases in mitochondria.

OMA1 Antigen Profile

Protein Summary

Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions (By similarity).

Gene names and symbols associated with OMA1

  • zinc metallopeptidase homolog (S. cerevisiae) (Oma1) antibody
  • OMA1 homolog, zinc metallopeptidase (S. cerevisiae) (OMA1) antibody
  • OMA1 homolog, zinc metallopeptidase (S. cerevisiae) (Oma1) antibody
  • OMA1 zinc metallopeptidase (OMA1) antibody
  • 2010001O09Rik antibody
  • DAB1 antibody
  • MPRP-1 antibody
  • peptidase antibody
  • RGD1304821 antibody
  • YKR087C antibody
  • ZMPOMA1 antibody

Protein level used designations for OMA1

OMA1 homolog, zinc metallopeptidase , metalloendopeptidase OMA1, mitochondrial , overlapping with the m-AAA protease 1 homolog , OMA1 zinc metallopeptidase homolog , metalloprotease related protein 1 , metalloprotease-related protein 1 , overlapping activity with M-AAA protease , zinc metallopeptidase OMA1

298282 Rattus norvegicus
506223 Bos taurus
67013 Mus musculus
115209 Homo sapiens
Selected quality suppliers for anti-OMA1 (OMA1) Antibodies
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