OMA1 antibody (AA 22-194) (Biotin)

Catalog No. ABIN7159466

Product Details anti-OMA1 Antibody (Biotin)

Target: OMA1 (OMA1 Zinc Metallopeptidase Homolog (OMA1))

Binding Specificity: AA 22-194

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OMA1 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Metalloendopeptidase OMA1, mitochondrial protein (22-194AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for OMA1

Target: OMA1 (OMA1 Zinc Metallopeptidase Homolog (OMA1))

Alternative Name: OMA1 (OMA1 Products)

Synonyms: 2010001O09Rik antibody, DAB1 antibody, MPRP-1 antibody, YKR087C antibody, ZMPOMA1 antibody, peptidase antibody, RGD1304821 antibody, oma1 antibody, OMA1 zinc metallopeptidase antibody, si:ch73-215a11.1 antibody, olfactory receptor 4K2 antibody, OMA1 antibody, Oma1 antibody, si:ch73-215a11.1 antibody, LOC531304 antibody

Background:

Background: Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.

Aliases: 2010001O09Rik antibody, DAB1 antibody, FLJ33782 antibody, Metalloendopeptidase OMA1 antibody, Metalloendopeptidase OMA1, mitochondrial antibody, Metalloprotease-related protein 1 antibody, mitochondrial antibody, MPRP 1 antibody, MPRP-1 antibody, MPRP1 antibody, OMA1 antibody, OMA1 homolog zinc metallopeptidase antibody, OMA1 homolog, zinc metallopeptidase (S. cerevisiae) antibody, OMA1 zinc metallopeptidase antibody, OMA1 zinc metallopeptidase homolog antibody, OMA1_HUMAN antibody, Overlapping activity with M-AAA protease antibody, Overlapping with the m-AAA protease 1 homolog antibody, peptidase antibody, YKR087C antibody, Zinc metallopeptidase OMA1 antibody, ZMPOMA1 antibody

UniProt: Q96E52