anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) Antibodies

The protein encoded by PAK7 is a member of the PAK family of Ser/Thr protein kinases. Additionally we are shipping PAK7 Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PAK7 57144 Q9P286
PAK7 241656 Q8C015
PAK7 311450 D4A280
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Top anti-PAK7 Antibodies at

Showing 10 out of 95 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-PAK5 Pab (ABIN392438) in lysates from transiently transfected COS7 cells. Lane 1: negative control, Lane 2: PAK1-expressing cells, Lane 3: PAK2-expressing cells, Lane 4: PAK4-expressing cells, Lane 5: PAK5-expressing cells, and Lane 6: PAK6-expressing cells. PAK5 (arrow) was detected using purified polyclonal antibody. Data is kindly provided by Drs. Z.M. Jaffer and J. Chernoff from the Fox Chase Cancer Center (Philadelphia, PA). Formalin-fixed and paraffin-embedded human brain tissue reacted with PAK5 antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated EIA, IP, WB 0.4 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IHC (p), WB Anti- PAK5 Picoband antibody, IHC(P) IHC(P): Human Glioma Tissue 100 μg Log in to see 4 to 6 Days
Human Rabbit Un-conjugated IHC (p), WB Mouse Pak7 Antibody (N-term) (ABIN657995) western blot analysis in mouse stomach tissue lysates (35 µg/lane). This demonstrates the Pak7 antibody detected the Pak7 protein (arrow). 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated ELISA, IHC, WB Western Blot (WB) analysis of specific cells using PAK5 Polyclonal Antibody. 100 μL Log in to see 16 Days
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated EIA, IF, WB   0.1 mg Log in to see 12 to 15 Days
Human Rabbit Un-conjugated IF, IHC (p), WB 50 μg Log in to see 6 to 8 Days
Dog Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of PAK7 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of PAK7 expression in SKNSH (A), K562 (B), COS7 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days

PAK7 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,

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Mouse (Murine) ,

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Rat (Rattus) ,

Top referenced anti-PAK7 Antibodies

  1. Human Polyclonal PAK7 Primary Antibody for EIA, IP - ABIN360325 : Pandey, Dan, Kristiansen, Watanabe, Voldby, Kajikawa, Khosravi-Far, Blagoev, Mann: Cloning and characterization of PAK5, a novel member of mammalian p21-activated kinase-II subfamily that is predominantly expressed in brain. in Oncogene 2002 (PubMed)
    Show all 4 references for 360325

  2. Human Polyclonal PAK7 Primary Antibody for IHC, ELISA - ABIN1452093 : Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: The DNA sequence and comparative analysis of human chromosome 20. ... in Nature 2002 (PubMed)
    Show all 2 references for 1452093

  3. Human Polyclonal PAK7 Primary Antibody for IHC (p), WB - ABIN392438 : Jaffer, Chernoff: p21-activated kinases: three more join the Pak. in The international journal of biochemistry & cell biology 2002 (PubMed)
    Show all 2 references for 392438

More Antibodies against PAK7 Interaction Partners

Human P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) interaction partners

  1. Data suggest expression of ECAD (E-cadherin (show CDH1 Antibodies)) in bladder cancer cell lines correlates with presence of intercellular junctions and level of PAK5 (show PAK6 Antibodies) (p21 (show CDKN1A Antibodies)-activated kinase PAK5 (show PAK6 Antibodies) protein) expression; endogenous PAK5 (show PAK6 Antibodies) is localized to intercellular junctions and interacts with ECAD (show CDH1 Antibodies); depletion of PAK5 (show PAK6 Antibodies) expression reduces integrity of intercellular junctions; PAK5 (show PAK6 Antibodies) mRNA levels are reduced in bladder cancer compared with normal controls.

  2. model suggests PAK5 self-association interferes with AID binding to the catalytic domain, thus maintaining its high activity.

  3. PAK7 expression is significantly downregulated in human masticatory mucosa during wound healing

  4. PAK7 is overexpressed in human esophageal squamous cell cancer samples and correlated with lymph node metastasis.

  5. E47 (show TCF3 Antibodies) is a novel substrate of PAK5 (show PAK6 Antibodies), and PAK5 (show PAK6 Antibodies)-mediated phosphorylation of E47 (show TCF3 Antibodies) promotes epithelial-mesenchymal transition and metastasis of colon cancer.

  6. Aurora-A induced PAK7 expression in esophageal cancer cells.

  7. results suggest that the inhibition of PAK5 by RNA interference might efficiently suppress tumor development of glioma cells with PAK5 high expression.

  8. miR-129 suppresses tumor cell growth and invasion by targeting PAK5 in hepatocellular carcinoma.

  9. PAK7 promotes cell proliferation and tumorigenesis

  10. It inhibits glioma cell migration and invasion potentially through the PAK5 (show PAK6 Antibodies)-Egr1 (show EGR1 Antibodies)-MMP2 (show MMP2 Antibodies) signaling pathway.

Mouse (Murine) P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) interaction partners

  1. PAK-7 p21-activated kinase 5 knockout mice are more sensitive to the stimulant effects of amphetamine

  2. functional deficits in PAK5, PAK6 (show PAK6 Antibodies) and PAK5/PAK6 (show PAK6 Antibodies) knockout mice

  3. PAK 5 is involved in formalin-induced inflammatory nociception through regulation of MAPK-induced c-Fos-activation and formalin-specific transient receptor potential-channels.

  4. These results implicate Pak5 in Pacsin1 (show PACSIN1 Antibodies)- and Synaptojanin1-mediated synaptic vesicle trafficking.

  5. PAK5 may provide a molecular rationale for late-stage complications in diabetes.

  6. Our results indicate that Pak5 and Pak6 (show PAK6 Antibodies) together are not required for viability, but are required for a normal level of locomotion and activity as well as for learning and memory.

PAK7 Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.

Gene names and symbols associated with PAK7

  • p21 protein (Cdc42/Rac)-activated kinase 7 (PAK7) antibody
  • p21 protein (Cdc42/Rac)-activated kinase 7 (Pak7) antibody
  • 2900083L08Rik antibody
  • 6430627N20 antibody
  • PAK-5 antibody
  • PAK-7 antibody
  • Pak5 antibody

Protein level used designations for PAK7

PAK-5 , PAK-7 , p21(CDKN1A)-activated kinase 7 , p21-activated kinase 5 , p21-activated kinase 7 , p21CDKN1A-activated kinase 7 , protein kinase PAK5 , serine/threonine-protein kinase PAK 7 , serine/threonine-protein kinase PAK7 , p21 (CDKN1A)-activated kinase 7

57144 Homo sapiens
241656 Mus musculus
311450 Rattus norvegicus
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