PAK7 antibody (AA 168-198)

Catalog No. ABIN3032113

This Rabbit Polyclonal antibody specifically detects PAK7 in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for PAK7 antibody (AA 168-198) (ABIN3032113)

Target: PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAK7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-PAK7 Antibody

Binding Specificity: AA 168-198

Purpose: PAK5 Antibody

Purification: Purified

Immunogen: A portion of amino acids 168-198 from the human protein was used as the immunogen for this PAK5 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the PAK5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the PAK5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for PAK7

Target: PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))

Alternative Name: PAK5

Background: PAK5 is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression.

UniProt: Q9P286