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anti-PTEN Induced Putative Kinase 1 (PINK1) Antibodies

PINK1 encodes a serine/threonine protein kinase that localizes to mitochondria. Additionally we are shipping PINK1 Proteins (12) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PINK1 65018 Q9BXM7
PINK1 68943 Q99MQ3
PINK1 298575  
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Top anti-PINK1 Antibodies at antibodies-online.com

Showing 10 out of 175 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Rat Goat Un-conjugated ELISA, WB ABIN334460 (1µg/ml) staining of Rat Testis lysate (35µg protein in RIP... 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with ... Western blot analysis of anti-PARK6 Pab in mouse kidney tissue lysate.... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of Park6 (PINK1) C-term (ABIN652208) in mouse ki... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Hamster Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB The anti-PINK1 C-term Pab (ABIN1882117) is used in Western blot to det... The anti-PINK1 C-term Pab (ABIN1882117) is used in Western blot to det... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$283.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IHC (p), WB (LEFT) Western blot analysis of anti-PINK1 Monoclonal Antibody (ABIN38... 0.1 mL Log in to see 10 to 11 Days
$324.50
Details

PINK1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
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Mouse (Murine) , , , ,
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Rat (Rattus) , , , ,
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Top referenced anti-PINK1 Antibodies

  1. Human Polyclonal PINK1 Primary Antibody for WB - ABIN1882117 : Rogaeva, Johnson, Lang, Gulick, Gwinn-Hardy, Kawarai, Sato, Morgan, Werner, Nussbaum, Petit, Okun, McInerney, Mandel, Groen, Fernandez, Postuma, Foote: Analysis of the PINK1 gene in a large cohort of cases with Parkinson disease. in Archives of neurology 2004 (PubMed)
    Show all 4 references for ABIN1882117

  2. Human Polyclonal PINK1 Primary Antibody for EIA, IHC (p) - ABIN358994 : Hatano, Li, Sato, Asakawa, Yamamura, Tomiyama, Yoshino, Asahina, Kobayashi, Hassin-Baer, Lu, Ng, Rosales, Shimizu, Toda, Mizuno, Hattori: Novel PINK1 mutations in early-onset parkinsonism. in Annals of neurology 2004 (PubMed)
    Show all 2 references for ABIN358994

  3. Rat (Rattus) Polyclonal PINK1 Primary Antibody for ELISA, WB - ABIN334460 : Chishti, Bohlega, Ahmed, Loualich, Carroll, Sato, St George-Hyslop, Westaway, Rogaeva: T313M PINK1 mutation in an extended highly consanguineous Saudi family with early-onset Parkinson disease. in Archives of neurology 2006 (PubMed)

  4. Human Polyclonal PINK1 Primary Antibody for WB - ABIN652208 : Berthier, Jiménez-Sáinz, Pulido: PINK1 regulates histone H3 trimethylation and gene expression by interaction with the polycomb protein EED/WAIT1. in Proceedings of the National Academy of Sciences of the United States of America 2013 (PubMed)

More Antibodies against PINK1 Interaction Partners

Fruit Fly (Drosophila melanogaster) PTEN Induced Putative Kinase 1 (PINK1) interaction partners

  1. Clu (show CLU Antibodies) directly modulates mitochondrial function, and that Clu's function contributes to the PINK1-Park pathway of mitochondrial quality control.

  2. Human Mask homolog ANKHD1 (show ANKHD1 Antibodies) may serve as a potential therapeutic target for treating Parkinson disease caused by pink1/parkin (show PARK2 Antibodies) mutations.

  3. Various ways of stimulation of the ETC (genetic, pharmacologic and mechanical) (Figure 1) all improve a Pink1 fly model.

  4. These results indicate that the in vivo rescue is due to restoring CI activity rather than promoting mitophagy Our findings support the emerging view that PINK1 plays a role in regulating complex I activity separate from its role with Parkin (show PARK2 Antibodies) in mitophagy

  5. MUL1 (show MUL1 Antibodies) acts in parallel to the PINK1/parkin (show PARK2 Antibodies) pathway on a shared target mitofusin (show MFN2 Antibodies) to maintain mitochondrial integrity.

  6. PINK1-mediated phosphorylation of Miro inhibits synaptic growth and protects dopaminergic neurons in Drosophila.

  7. PINK1 cooperates with Parkin to promote hnRNP-F/Glo ubiquitination and nRCC mRNA translation.

  8. results strongly circumscribe the possible mechanisms of PINK1 action in the mitochondrial life cycle

  9. PINK1 counteracts the neurotoxicity of PINK1 counteracts the neurotoxicity of mutant Htt (show HTT Antibodies).

  10. Parkin (show PARK2 Antibodies) phosphorylation by PINK1 drives Parkin (show PARK2 Antibodies) E3 activity. endogenous PINK1 precisely controls Parkin (show PARK2 Antibodies) activity to maintain the mitochondrial function in muscle tissue and the neuronal function in dopaminergic neurons.

Zebrafish PTEN Induced Putative Kinase 1 (PINK1) interaction partners

  1. Pink1-depleted zebrafish are the first vertebrate model of PINK1 deficiency with loss of dopaminergic neurons.

  2. Our findings suggest that a lack of pink1 in zebrafish alters many vital and critical pathways in addition to the HIF signaling pathway.

  3. Distinct groups of dopaminergic neurons are sensitive to targeted loss of Pink1 factor in a morphant fish model of toxin-induced Parkinson's disease.

  4. Morpholino-mediated loss of pink1 function in zebrafish profoundly affects the development of dopaminergic neurons in the ventral diencephalon and affects behaviour of the zebrafish larvae, namely their response to tactile stimuli and locomotor behavior.

Human PTEN Induced Putative Kinase 1 (PINK1) interaction partners

  1. Processing and shuttling of PINK1 through mitochondria is conformed to at least three possible functional microcompartments for PINK1 activity (I, cytosol; II, outer mitochondrial membrane; III, inside mitochondria).

  2. pathogenic PINK1 mutants which are not cleaved by PARL (show PARL Antibodies) affect PINK1 kinase activity and the ability to induce PARK2 (show PARK2 Antibodies)-mediated mitophagy.

  3. results indicate that PINK1 expression is positively regulated by NRF2 (show GABPA Antibodies) and that the NRF2 (show GABPA Antibodies)-PINK1 signaling axis is deeply involved in cell survival.

  4. High expression of PARK6 might lead to the occurrence of non-small-cell lung cancer.

  5. These results suggest that pyruvate is required for CCCP-induced PINK1/PARK2 (show PARK2 Antibodies)-mediated mitophagy.

  6. PINK1-PARK2 (show PARK2 Antibodies) pathway-mediated mitophagy plays a key regulatory role in CSE-induced mitochondrial ROS (show ROS1 Antibodies) production and cellular senescence in human bronchial epithelial cells

  7. Rab8A (show RAB8A Antibodies) GTPase (show RACGAP1 Antibodies) Ser (show SIGLEC1 Antibodies)(111) phosphorylation is not directly regulated by PINK1 in vitro and demonstrate in cells the time course of Ser (show SIGLEC1 Antibodies)(111) phosphorylation of Rab8A (show RAB8A Antibodies), 8B and 13 is markedly delayed compared to phosphorylation of Parkin (show PARK2 Antibodies) at Ser (show SIGLEC1 Antibodies)(65).

  8. mutant G309D PINK1 significantly reduced phosphorylation of GSK3beta (show GSK3b Antibodies) at serine 9, suggesting that alterations in GSK3beta (show GSK3b Antibodies) activity play an essential role in mutant G309D PINK1-induced tau phosphorylation at the PHF-1 (show PHF1 Antibodies) site

  9. TGF-beta1 (show TGFB1 Antibodies) induces lung epithelial cell mitochondrial ROS (show ROS1 Antibodies) and depolarization and stabilizes the key mitophagy initiating protein, PINK1

  10. The results of the combined in silico simulations-based and experimental assay-based study indicates that PINK1-dependent Ser65 phosphorylation of Parkin (show PARK2 Antibodies) is required for its activation and triggering of 'opening' conformations.

Mouse (Murine) PTEN Induced Putative Kinase 1 (PINK1) interaction partners

  1. Loss of PINK1 inhibits Ca2 (show CA2 Antibodies)+ efflux by NCLX (show SLC24A6 Antibodies) and triggers mitochondrial depolarization.

  2. PINK1 gene knockout can protect neonatal mice from hypoxic-ischemic brain damage (HIBD).

  3. Loss of Pink1 reprograms glucose metabolism through HIF1alpha (show HIF1A Antibodies), sustaining increased cell proliferation.

  4. findings support the notion that BAG2 (show BAG2 Antibodies) is an upstream regulator of the PINK1/PARKIN (show PARK2 Antibodies) signaling pathway.

  5. Interplay between E2F1 (show E2F1 Antibodies), miR421 and Pink1 regulates mitochondrial morphology and cardiomyocyte death. Pink1 reduces mitochondrial fragmentation and protects cardiomyocyte from apoptosis.

  6. data suggest that Parkin (show PARK2 Antibodies) recruitment to depolarized cardiac mitochondria and subsequent activation of mitophagy is independent of PINK1.

  7. The PINK1-Parkin (show PARK2 Antibodies) pathway is activated in response to metabolic stress

  8. TGF-beta1 (show TGFB1 Antibodies) induces lung epithelial cell mitochondrial ROS (show ROS1 Antibodies) and depolarization and stabilizes the key mitophagy initiating protein, PINK1

  9. our study demonstrates that BNIP3L (show BNIP3L Antibodies), as a substrate of PARK2 (show PARK2 Antibodies), promotes mitophagy in the PINK1/PARK2 (show PARK2 Antibodies) pathway associated with PD pathogenesis.

  10. Cytosolic PINK1 is stabilized by TRAF6 (show TRAF6 Antibodies)/NF-kappaB (show NFKB1 Antibodies) activation via Lys (show LYZ Antibodies)-63-linked ubiquitination.

PINK1 Antigen Profile

Protein Summary

This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease.

Gene names and symbols associated with PINK1

  • PTEN-induced putative kinase 1 (Pink1) antibody
  • PTEN induced putative kinase 1 (PINK1) antibody
  • PTEN induced putative kinase 1 (pink1) antibody
  • PTEN induced putative kinase 1 (Pink1) antibody
  • 1190006F07Rik antibody
  • AU042772 antibody
  • AW557854 antibody
  • BEST:GH23468 antibody
  • BRPK antibody
  • CG4523 antibody
  • Dmel\\CG4523 antibody
  • dPink1 antibody
  • mFLJ00387 antibody
  • PARK6 antibody
  • PINK antibody
  • pink1 antibody
  • wu:fc39e12 antibody
  • zgc:101729 antibody

Protein level used designations for PINK1

CG4523-PA , CG4523-PB , CG4523-PC , CG4523-PD , CG4523-PE , CG4523-PF , CG4523-PG , CG4523-PH , PTEN induced putative kinase 1 , PTEN-Induced kinase 1 , Pink1-PA , Pink1-PB , Pink1-PC , Pink1-PD , Pink1-PE , Pink1-PF , Pink1-PG , Pink1-PH , PTEN-induced putative kinase 1 , serine/threonine-protein kinase PINK1, mitochondrial , serine/threonine-protein kinase PINK1, mitochondrial-like , PTEN-induced putative kinase protein 1 , protein kinase BRPK

GENE ID SPECIES
31607 Drosophila melanogaster
425370 Gallus gallus
494085 Danio rerio
510683 Bos taurus
706037 Macaca mulatta
749028 Pan troglodytes
100027082 Monodelphis domestica
100412264 Callithrix jacchus
100443445 Pongo abelii
100465867 Ailuropoda melanoleuca
65018 Homo sapiens
68943 Mus musculus
298575 Rattus norvegicus
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