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anti-Poliovirus Receptor-Related 4 (PVRL4) Antibodies

PVRL4 encodes a member of the nectin family. Additionally we are shipping PVRL4 Proteins (13) and PVRL4 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PVRL4 71740 Q8R007
PVRL4 498281  
PVRL4 81607 Q96NY8
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Top anti-PVRL4 Antibodies at antibodies-online.com

Showing 10 out of 58 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, using PVRL4 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB PVRL4 Antibody (Center)  western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the PVRL4 antibody detected the PVRL4 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Goat Un-conjugated FACS, IHC, WB 100 μg Log in to see 8 to 10 Days
$595.83
Details
Human Mouse Un-conjugated FACS, ELISA, WB   100 μg Log in to see 8 to 10 Days
$793.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 2 µg/100 µL Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000, Secondary: HRP conjugated Rabbit Anti-Goat IgG at 1: 5000, TMB staining Read the data in Microplate Reader by 450 nm. 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.73 KDa) . 200 μL Log in to see 9 Days
$430.00
Details
Mouse Rat Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$793.83
Details
Human Rabbit Biotin ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

PVRL4 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-PVRL4 Antibodies

  1. Human Polyclonal PVRL4 Primary Antibody for ELISA, WB - ABIN1535179 : Gregory, Barlow, McLay, Kaul, Swarbreck, Dunham, Scott, Howe, Woodfine, Spencer, Jones, Gillson, Searle, Zhou, Kokocinski, McDonald, Evans, Phillips, Atkinson, Cooper, Jones, Hall, Andrews, Lloyd et al.: The DNA sequence and biological annotation of human chromosome 1. ... in Nature 2006 (PubMed)

More Antibodies against PVRL4 Interaction Partners

Mouse (Murine) Poliovirus Receptor-Related 4 (PVRL4) interaction partners

  1. Novel type of cell adhesion apparatus is mediated by Nectin-1 (show PVRL1 Antibodies) and Nectin-4. It's implicated in prolactin receptor (show PRLR Antibodies) signaling for mammary gland development.

  2. Pvrl1 (show PVRL1 Antibodies) is a bona fide target gene of the transcription factor p63 (show CKAP4 Antibodies), whereas Pvrl4 regulation is linked to epidermal differentiation and is under Irf6 (show IRF6 Antibodies)

  3. Mouse PVRL4 functions less efficiently as a receptor for measles virus than the human homologue.

  4. Ectodermal dysplasia-syndactyly syndrome is the second known "nectinopathy" caused by mutations in a nectin (show PVRL1 Antibodies) adhesion molecule (show NCAM1 Antibodies).

Human Poliovirus Receptor-Related 4 (PVRL4) interaction partners

  1. The data presented in this study suggested that nectin-4 may be a therapeutic target for systemic lupus erythematous through affecting the cell apoptosis

  2. Nectin-4 is critical for gallbladder cancer cell progression via PI3K/AKT pathway activation of Rac1.

  3. Nectin-4 expression, when compared with control group, was higher in endometriotic lesions of patients having ovarian endometriosis and peritoneal endometriosis. This difference was significant in the endometrium of patients having endometriosis.

  4. Transformation of breast cancer cells is dependent on PVRL4.

  5. Nectin-4 is a significant prognostic predictor, and may play a critical role in pancreatic cancer. Nectin-4 may be novel therapeutic target for pancreatic cancer.

  6. In airway epithelial cells, measles virus spread requires the nectin-4/afadin (show MLLT4 Antibodies) complex and is based on cytoplasm transfer between columnar cells.

  7. The present study described clinical investigation of the EDSS1 identified in a large consanguineous family; DNA sequence analysis revealed a novel homozygous nonsense mutation (181C>T, p.Asp61*) in the PVRL4 gene.

  8. Ovarian tissue expression and serum nectin 4 appear to be potential markers in ovarian cancer.

  9. Authors show that the same key residues in the BC and FG loops of nectin-4 govern binding to the measles virus attachment protein hemagglutinin (show HA Antibodies) (H) and cell entry, nectin-4 homodimerization, and heterodimerization with nectin-1 (show PVRL1 Antibodies).

  10. data outline a synergistic action of nectin-1 and -4 in the early steps of AJ formation and implicate this interaction in modulating the Rac1 signaling pathway

PVRL4 Antigen Profile

Protein Summary

This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.

Gene names and symbols associated with PVRL4

  • poliovirus receptor-related 4 (PVRL4) antibody
  • poliovirus receptor-related 4 (pvrl4) antibody
  • poliovirus receptor-related 4 (LOC100348580) antibody
  • poliovirus receptor-related 4 (Pvrl4) antibody
  • 1200017F15Rik antibody
  • EDSS1 antibody
  • LNIR antibody
  • nectin-4 antibody
  • PRR4 antibody
  • PVRL4 antibody
  • RGD1559826 antibody
  • si:ch211-155e24.1 antibody

Protein level used designations for PVRL4

poliovirus receptor-related 4 , poliovirus receptor-related protein 4-like , ig superfamily receptor LNIR , nectin 4 , nectin-4 , poliovirus receptor-related protein 4 , Ig superfamily receptor LNIR

GENE ID SPECIES
609931 Canis lupus familiaris
794920 Danio rerio
100032730 Monodelphis domestica
100066309 Equus caballus
100348580 Oryctolagus cuniculus
100435072 Pongo abelii
71740 Mus musculus
498281 Rattus norvegicus
81607 Homo sapiens
507718 Bos taurus
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