Poly-U Binding Splicing Factor 60KDa (PUF60) ELISA Kits

PUF60 encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. Additionally we are shipping PUF60 Antibodies (130) and PUF60 Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse PUF60 PUF60 67959 Q3UEB3
Anti-Rat PUF60 PUF60 84401  
Anti-Human PUF60 PUF60 22827 Q9UHX1
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Top PUF60 ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Cow 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days

More ELISA Kits for PUF60 Interaction Partners

Human Poly-U Binding Splicing Factor 60KDa (PUF60) interaction partners

  1. These results confirm that PUF60 is a major driver for the developmental, craniofacial, skeletal and cardiac phenotypes associated with the 8q24.3 microdeletion

  2. Heterozygote loss-of-function variants in PUF60 cause a phenotype comprising growth/developmental delay and craniofacial, cardiac, renal, ocular and spinal anomalies.

  3. Mutations in PUF60 gene is associated with idiopathic hypereosinophilic syndrome.

  4. Concomitant over expression of far upstream element (FUSE) binding protein (FBP) interacting repressor (FIR) and its splice variants induce migration and invasion of non-small cell lung cancer cells.

  5. Overexpression of far upstream element (FUSE) binding protein (FBP)-interacting repressor (FIR) supports growth of hepatocellular carcinoma.

  6. High FBP-interacting repressor expression is associated with hepatocellular carcinoma.

  7. The interaction between SAP155 and FIR/FIRDeltaexon2 not only integrates cell-cycle progression and c-Myc transcription by modifying P27 and P89 expression.

  8. Haploinsufficiency of each of SCRIB (show SCRIB ELISA Kits) or PUF60 contribute uniquely to specific endophenotypes (e.g., coloboma, heart defects), and binary interaction potentially exacerbates other aspects of the clinical pathology of individuals with 8q24.3 deletion.

  9. Circulating FIR (show FARP2 ELISA Kits) variant mRNA in the peripheral blood of cancer patients were significantly overexpressed compared to that in healthy volunteers.

  10. Data indicate that altered FIR (show FARP2 ELISA Kits) and c-myc (show MYC ELISA Kits) pre-mRNA splicing, in addition to c-Myc (show MYC ELISA Kits) expression by augmented FIR (show FARP2 ELISA Kits)/FIRDeltaexon2-SAP155 (show SF3B1 ELISA Kits) complex, potentially contribute to colorectal cancer development.

PUF60 Antigen Profile

Antigen Summary

This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with PUF60

  • poly-U binding splicing factor 60 (Puf60) antibody
  • poly(U) binding splicing factor 60 (PUF60) antibody
  • 2410104I19Rik antibody
  • 2810454F19Rik antibody
  • FIR antibody
  • RoBPI antibody
  • Siahbp1 antibody

Protein level used designations for PUF60

60 kDa poly(U)-binding-splicing factor , fuse-binding protein-interacting repressor , poly(U)-binding-splicing factor PUF60 , FBP interacting repressor , RNA-binding protein Siah-BP , Ro ribonucleoprotein-binding protein 1 , poly-U binding splicing factor 60K , pyrimidine tract binding splicing factor , siah binding protein 1; FBP interacting repressor; pyrimidine tract binding splicing factor; Ro ribonucleoprotein-binding protein 1 , siah-binding protein 1 , FUSE-binding protein-interacting repressor , Siah binding protein 1

67959 Mus musculus
84401 Rattus norvegicus
22827 Homo sapiens
607245 Canis lupus familiaris
512824 Bos taurus
100174042 Pongo abelii
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