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POMC ELISA Kits

(Proopiomelanocortin (POMC))

This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used\; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008].

recommended

POMC ELISA Kit (ABIN6958845)

POMC Reactivity: Human Colorimetric Competition ELISA 123.5 pg/mL - 10000 pg/mL Plasma, Serum

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recommended

POMC ELISA Kit (ABIN848183)

POMC Reactivity: Mouse Colorimetric Competition ELISA 0.73-3000 pg/mL Cell Culture Supernatant, Plasma, Serum, Tissue Homogenate

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recommended

POMC ELISA Kit (ABIN6969633)

POMC Reactivity: Human Colorimetric Sandwich ELISA 0.156 ng/mL - 10 ng/mL Plasma, Serum, Tissue Homogenate

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POMC ELISA Kits by Reactivity

Find POMC ELISA Kits for a variety of species such as anti-Human POMC, anti-Mouse POMC, anti-Pig POMC. The species listed below are among those available. Click on a link to go to the corresponding products.

POMC ELISA Kits by Detection Method

Find POMC ELISA Kits with a specific Detection Method. The Detection Method listed below are among those available. Click on a link to go to the corresponding products.

POMC ELISA Kits by Analytical Method

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POMC ELISA Kits by Method Type

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POMC ELISA Kits by Sample

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