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anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) Antibodies

The product of P2RY12 belongs to the family of G-protein coupled receptors. Additionally we are shipping P2RY12 Kits (18) and P2RY12 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
P2RY12 70839 Q9CPV9
P2RY12 64805 Q9H244
P2RY12 64803 Q9EPX4
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Top anti-P2RY12 Antibodies at antibodies-online.com

Showing 10 out of 31 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated DB, ELISA, ICC, IF, IHC, IHC (p), IP, WB Western Blot: P2Y12/P2RY12 Antibody [NBP1-78249] - Antibody dilution 1:500, MW is 41 kDa Immunohistochemistry-Paraffin: P2Y12/P2RY12 Antibody [NBP1-78249] - Rat spinal cord. Dilution 1:100. 0.1 mg Log in to see 8 to 11 Days
$603.75
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: P2Y12 Antibody [NBP1-89673] - Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in reaction center cells, lymphoid cells outside reaction centra. Western Blot: P2Y12 Antibody [NBP1-89673] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted).Lane 5: Human liver tissue 0.1 mL Log in to see 8 to 11 Days
$439.69
Details
Human Rabbit Un-conjugated IF, IHC (p) Immunohistochemical staining of Blood (Platelets) using anti- P2RY12 antibody ABIN122358 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p) Anti-P2RY12 / P2Y12 antibody  ABIN1049208 IHC staining of human bone marrow, megakaryocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated ICC, IHC (p) Anti-P2RY12 / P2Y12 antibody  ABIN1049207 IHC staining of human blood, platelets. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ICC, IHC (p) Immunohistochemistry-Paraffin: P2Y12/P2RY12 Antibody [NLS3742] - Analysis of anti-P2RY12 / P2Y12 antibody with human brain, glioblastoma. Immunocytochemistry: P2Y12/P2RY12 Antibody [NLS3742] - Analysis of anti-P2RY12 / P2Y12 antibody with HEK293 human embryonic kidney cells 0.05 mL Log in to see 8 to 11 Days
$447.56
Details
Human Rabbit Un-conjugated WB Western Blot: P2Y12 Antibody [NBP2-19660] - Sample (30 ug of whole cell lysate) A: NT2D1 B: PC-3 C: U87-MG D: SK-N-SH 10% SDS PAGE gel, diluted at 1:1000. 0.1 mL Log in to see 6 to 9 Days
$447.56
Details
Human Rabbit HRP IHC (p), WB   100 μL Log in to see 14 to 21 Days
$379.50
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: P2Y12 Antibody [NBP2-33870] - liver cancer Immunohistochemistry: P2Y12 Antibody [NBP2-33870] - Immunohistochemical staining of human cerebral cortex shows positivity in microglia. 0.1 mL Log in to see 8 to 11 Days
$439.69
Details

P2RY12 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Human , ,


, ,
Rat (Rattus)


, ,

Top referenced anti-P2RY12 Antibodies

  1. Human Polyclonal P2RY12 Primary Antibody for DB, ELISA - ABIN4342653 : Abbracchio, Burnstock: Purinoceptors: are there families of P2X and P2Y purinoceptors? in Pharmacology & therapeutics 1995 (PubMed)

  2. Human Polyclonal P2RY12 Primary Antibody for IHC, IHC (p) - ABIN4342655 : Bornø, Ploug, Bune, Rosenmeier, Thaning: Purinergic receptors expressed in human skeletal muscle fibres. in Purinergic signalling 2012 (PubMed)

More Antibodies against P2RY12 Interaction Partners

Mouse (Murine) Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) interaction partners

  1. AHR (show AHR Antibodies) and airway inflammation in a mouse model of asthma. P2Y12 can be a novel therapeutic target to the suppression of eosinophils in asthma.

  2. quinine/bupivacaine-sensitive potassium channels are the functional effectors of the P2Y12R-mediated signaling in microglia activation following neuronal injury

  3. Disrupting P2Y12 alters the microglial response to monocular deprivation and abrogates ocular dominance plasticity.

  4. P2RY12-mediated activation of juxtavascular microglial cells contributes to the rapid closure of small openings in the BBB (show ALMS1 Antibodies).

  5. study reports robust involvement of P2Y12R in inflammatory pain: anti-hyperalgesic effect of P2Y12R antagonism could be mediated by the inhibition of both central and peripheral cytokine production and involves alpha7-receptor mediated efferent pathways

  6. demonstrating that these P2Y12 inhibitors may not be effective in preventing early disease

  7. indicate that P2Y12R undergoes slow desensitization; ADP-P2Y12 signaling is tightly regulated by Entpd1 (show ENTPD1 Antibodies)/Nt5e (show NT5E Antibodies) activity and adenosine receptors

  8. P2Y12 signaling is required for stabilizing platelet thrombi.

  9. Platelet P2Y12 is involved in murine pulmonary metastasis.

  10. The P2Y12 receptor plays an important role during lipopolysaccharide-induced inflammation.

Human Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) interaction partners

  1. No association was found in genotype frequencies of P2Y12 and responsiveness to clopidogrel in coronary heart disease patients of Han ethnicity.

  2. P2Y12 inhibitor monotherapy and dual antiplatelet therapy inhibit hemostatic system activation to a comparable extent in healthy volunteers.

  3. In the presence of loss of function C34T polymorphism of P2Y12 receptor, smoking is associated with increased adverse cardiovascular outcome in coronary artery disease patients.

  4. These data strongly suggest that P2Y12 may represent an important pharmacological target for the treatment of patients with allergic bronchial asthma. [review]

  5. Report appropriate P2Y12 inhibitor regimen to prevent increased bleeding risk and maintain antiplatelet efficacy in East Asian patients with acute coronary syndrome. in Korean patients

  6. Baseline platelet aggregation was increased in carriers of the common alleles of P2Y12 SNPs rs1907637, rs2046934, and rs6809699 and rs6787801 TC heterozygotes.

  7. The ratio of ADP- to TRAP-induced platelet aggregation quantifies P2Y12-dependent platelet inhibition independently of the platelet count in contrast to conventional ADP-induced aggregation.

  8. Synergistic inhibition of both P2Y1 (show P2RY1 Antibodies) and P2Y12 adenosine diphosphate receptors by GLS (show GLS Antibodies)-409 immediately attenuates platelet-mediated thrombosis and effectively blocks agonist-stimulated platelet aggregation irrespective of concomitant aspirin therapy.

  9. PON1 (show PON1 Antibodies), P2Y12 and COX1 (show COX1 Antibodies) polymorphisms were associated with poorer vascular outcomes in patients with extracranial or intracranial stents.

  10. In non-ST elevation acute coronary syndrome patients undergoing PCI a loading dose of ticagrelor or prasugrel given during the procedure provides optimal P2Y12-ADP receptor blockade in 2 h and maximal inhibition within 4 h.

P2RY12 Antigen Profile

Protein Summary

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified for this gene.

Gene names and symbols associated with P2RY12

  • purinergic receptor P2Y, G-protein coupled 12 (P2ry12) antibody
  • purinergic receptor P2Y, G-protein coupled, 12 (P2RY12) antibody
  • purinergic receptor P2Y, G-protein coupled, 12 (P2ry12) antibody
  • 2900079B22Rik antibody
  • 4921504D23Rik antibody
  • ADPG-R antibody
  • BDPLT8 antibody
  • HORK3 antibody
  • P2T(AC) antibody
  • P2Y(12)R antibody
  • P2Y(AC) antibody
  • P2Y(ADP) antibody
  • P2Y(cyc) antibody
  • P2y12 antibody
  • SP1999 antibody

Protein level used designations for P2RY12

P2Y purinoceptor 12 , ADP-glucose receptor , G-protein coupled receptor SP1999 , Gi-coupled ADP receptor HORK3 , P2Y12 platelet ADP receptor , purinergic receptor P2RY12 , putative G-protein coupled receptor

GENE ID SPECIES
70839 Mus musculus
64805 Homo sapiens
64803 Rattus norvegicus
442958 Canis lupus familiaris
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