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anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) Antibodies

The product of P2RY12 belongs to the family of G-protein coupled receptors. Additionally we are shipping Purinergic Receptor P2Y, G-Protein Coupled, 12 Kits (21) and Purinergic Receptor P2Y, G-Protein Coupled, 12 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
P2RY12 70839 Q9CPV9
P2RY12 64805 Q9H244
P2RY12 64803 Q9EPX4
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Top anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 Antibodies at antibodies-online.com

Showing 10 out of 27 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, IHC (p) Immunohistochemical staining of Blood (Platelets) using anti- P2RY12 a... 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p) Anti-P2RY12 / P2Y12 antibody  ABIN1049208 IHC staining of human bone m... 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ICC, IHC (p) Anti-P2RY12 / P2Y12 antibody  ABIN1049207 IHC staining of human blood,... 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB P2RY12 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit HRP IHC (p), WB   100 μL Log in to see 14 to 21 Days
$379.50
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated ICC, IHC (p) 50 μg Log in to see 11 to 13 Days
$541.80
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 11 to 13 Days
$541.80
Details

P2RY12 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) , ,

Human , , , ,

Rat (Rattus) , , , ,

More Antibodies against Purinergic Receptor P2Y, G-Protein Coupled, 12 Interaction Partners

Mouse (Murine) Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) interaction partners

  1. P2RY12-mediated activation of juxtavascular microglial cells contributes to the rapid closure of small openings in the BBB (show ALMS1 Antibodies).

  2. study reports robust involvement of P2Y12R in inflammatory pain: anti-hyperalgesic effect of P2Y12R antagonism could be mediated by the inhibition of both central and peripheral cytokine production and involves alpha7-receptor mediated efferent pathways

  3. demonstrating that these P2Y12 inhibitors may not be effective in preventing early disease

  4. indicate that P2Y12R undergoes slow desensitization; ADP-P2Y12 signaling is tightly regulated by Entpd1 (show ENTPD1 Antibodies)/Nt5e (show NT5E Antibodies) activity and adenosine receptors

  5. P2Y12 signaling is required for stabilizing platelet thrombi.

  6. Platelet P2Y12 is involved in murine pulmonary metastasis.

  7. The P2Y12 receptor plays an important role during lipopolysaccharide-induced inflammation.

  8. P2Y12 participates in ischemia related inflammation by mediating microglial migration and potentiation of neurotoxicity.

  9. This study demonistrated that environment enhanced P2Y12 expression in brain and enhanced totaroad perfermance and short term working menory.

  10. Epac (show RAPGEF3 Antibodies) agonist 8-pCPT-2'-O-Me-cAMP affects P2Y12 receptors in blood platelets

Human Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) interaction partners

  1. Baseline platelet aggregation was increased in carriers of the common alleles of P2Y12 SNPs rs1907637, rs2046934, and rs6809699 and rs6787801 TC heterozygotes.

  2. The ratio of ADP- to TRAP-induced platelet aggregation quantifies P2Y12-dependent platelet inhibition independently of the platelet count in contrast to conventional ADP-induced aggregation.

  3. Synergistic inhibition of both P2Y1 (show P2RY1 Antibodies) and P2Y12 adenosine diphosphate receptors by GLS (show GLS Antibodies)-409 immediately attenuates platelet-mediated thrombosis and effectively blocks agonist-stimulated platelet aggregation irrespective of concomitant aspirin therapy.

  4. PON1 (show PON1 Antibodies), P2Y12 and COX1 (show COX1 Antibodies) polymorphisms were associated with poorer vascular outcomes in patients with extracranial or intracranial stents.

  5. In non-ST elevation acute coronary syndrome patients undergoing PCI a loading dose of ticagrelor or prasugrel given during the procedure provides optimal P2Y12-ADP receptor blockade in 2 h and maximal inhibition within 4 h.

  6. While there is increasing evidence for the cancer-protective effect of aspirin, this study suggests P2Y12 inhibition may also play a role.

  7. Establish a reliable antiplatelet profile of SAR216471, and support its potential use in clinical practice as an alternative to currently available P2Y12 receptor antagonists.

  8. 2 functional single nucleotide polymorphisms of PON1 gene (rs662 and rs854560) and 3 variants of the P2RY12 gene (rs2046934, rs6798347, rs6801273) in samples pooled from average Hungarian Roma and Hungarian population samples, were investigated.

  9. coexisting polymorphisms of CYP3A5 (show CYP3A5 Antibodies)*3 and 2C19*2, but not P2Y12*1, play an important role in the variability of clopidogrel's curative effect

  10. ADP stimulation of P2Y12 led to cAMP decrease that, in turn, caused changes in phospholipase C (show PLC Antibodies) phosphorylation by protein kinase A, increase in cytoplasmic calcium level and, consequently, PS+ platelet formation

Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) Antigen Profile

Protein Summary

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified for this gene.

Gene names and symbols associated with P2RY12

  • purinergic receptor P2Y, G-protein coupled 12 (P2ry12) antibody
  • purinergic receptor P2Y, G-protein coupled, 12 (P2RY12) antibody
  • purinergic receptor P2Y, G-protein coupled, 12 (P2ry12) antibody
  • 2900079B22Rik antibody
  • 4921504D23Rik antibody
  • ADPG-R antibody
  • BDPLT8 antibody
  • HORK3 antibody
  • P2T(AC) antibody
  • P2Y(12)R antibody
  • P2Y(AC) antibody
  • P2Y(ADP) antibody
  • P2Y(cyc) antibody
  • P2y12 antibody
  • SP1999 antibody

Protein level used designations for P2RY12

P2Y purinoceptor 12 , ADP-glucose receptor , G-protein coupled receptor SP1999 , Gi-coupled ADP receptor HORK3 , P2Y12 platelet ADP receptor , purinergic receptor P2RY12 , putative G-protein coupled receptor

GENE ID SPECIES
70839 Mus musculus
64805 Homo sapiens
64803 Rattus norvegicus
442958 Canis lupus familiaris
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