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p130 Antibodies

(Retinoblastoma-Like 2 (p130) (RBL2))
Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. May act as a tumor suppressor.
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 939-1139) antibody anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 939-1139) antibody anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 939-1139) antibody (ABIN5542553)

RBL2 Reactivity: Human ELISA, FACS, WB Host: Mouse Monoclonal 2C8A8 unconjugated

anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 165-194), (N-Term) antibody anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 165-194), (N-Term) antibody anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 165-194), (N-Term) antibody (ABIN656158)

RBL2 Reactivity: Human FACS, WB Host: Rabbit Polyclonal RB31021 unconjugated

anti-Retinoblastoma-Like 2 (p130) (RBL2) (C-Term) antibody anti-Retinoblastoma-Like 2 (p130) (RBL2) (C-Term) antibody anti-Retinoblastoma-Like 2 (p130) (RBL2) (C-Term) antibody (ABIN106440)

RBL2 Reactivity: Human IP, ELISA, WB Host: Rabbit Polyclonal unconjugated

p130 Antibodies by Reactivity

Find p130 Antibodies for a variety of species such as anti-Human p130, anti-Rat p130, anti-Mouse p130. The species listed below are among those available. Click on a link to go to the corresponding products.

p130 Antibodies by Application

Find p130 Antibodies validated for a specific application such as WB, ELISA, FACS, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

p130 Antibodies by Host

Find p130 Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

p130 Antibodies by Binding Specificity

Find p130 Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

p130 Antibodies by Clonality

Find available monoclonal or polyclonal p130 Antibodies. Click on a link to go to the corresponding products.

p130 Antibodies by Clone

Find p130 Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

p130 Antibodies by Conjugate

Find p130 Antibodies with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular p130 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (2)
Cat. No. ABIN2780695
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application IF, IHC, IHC (p), IP, WB
Validations
  • (2)
Cat. No. ABIN1491690
Quantity 250 μL
Datasheet Datasheet
Reactivity Human, Chimpanzee
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN349607
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IF, ELISA
Validations
  • (1)
Cat. No. ABIN1532533
Quantity 100 μg
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN2777198
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN6264666
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN562603
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IC, IF, WB
Validations
  • (1)
Cat. No. ABIN2705177
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application IF, IP, WB
Validations
  • (1)
Cat. No. ABIN487489
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Monkey, Mouse
Application WB
Validations
  • (1)
Cat. No. ABIN5586825
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
  • (1)
Cat. No. ABIN519666
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IP, IHC, ELISA, WB
Validations
  • (1)
Cat. No. ABIN2470269
Quantity 0.05 mL
Datasheet Datasheet
Reactivity Human
Application EIA, WB
Validations
  • (1)
Cat. No. ABIN954473
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application IHC (p), WB
Validations
  • (1)
Cat. No. ABIN1738769
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Rat
Application IF, IHC (p), IP, WB
Validations
  • (1)
Cat. No. ABIN386791
Quantity 0.1 mL
Datasheet Datasheet

Latest Publications for our p130 Antibodies

Song, Gong, Yan, Hong, Wang, Wu, Li, Li, Cao: "Sj7170, a unique dual-function peptide with a specific ?-chymotrypsin inhibitory activity and a potent tumor-activating effect from scorpion venom." in: The Journal of biological chemistry, Vol. 289, Issue 17, pp. 11667-80, (2014) (PubMed).

Bagella, Sun, Tonini, Abbadessa, Cottone, Paggi, De Luca, Claudio, Giordano: "A small molecule based on the pRb2/p130 spacer domain leads to inhibition of cdk2 activity, cell cycle arrest and tumor growth reduction in vivo." in: Oncogene, Vol. 26, Issue 13, pp. 1829-39, (2007) (PubMed).

Sun, Bagella, Tutton, Romano, Giordano: "From G0 to S phase: a view of the roles played by the retinoblastoma (Rb) family members in the Rb-E2F pathway." in: Journal of cellular biochemistry, Vol. 102, Issue 6, pp. 1400-4, (2007) (PubMed).

DAndrilli, Masciullo, Bagella, Tonini, Minimo, Zannoni, Giuntoli, Carlson, Soprano, Soprano, Scambia, Giordano: "Frequent loss of pRb2/p130 in human ovarian carcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 10, Issue 9, pp. 3098-103, (2004) (PubMed).

Fusaro, Wang, Chellappan: "Differential regulation of Rb family proteins and prohibitin during camptothecin-induced apoptosis." in: Oncogene, Vol. 21, Issue 29, pp. 4539-48, (2002) (PubMed).

Saitoh, Pizzi, Wang: "Perturbation of SUMOlation enzyme Ubc9 by distinct domain within nucleoporin RanBP2/Nup358." in: The Journal of biological chemistry, Vol. 277, Issue 7, pp. 4755-63, (2002) (PubMed).

Laplantine, Rossi, Sahni, Basilico, Cobrinik: "FGF signaling targets the pRb-related p107 and p130 proteins to induce chondrocyte growth arrest." in: The Journal of cell biology, Vol. 158, Issue 4, pp. 741-50, (2002) (PubMed).

Claudio, Tonini, Giordano: "The retinoblastoma family: twins or distant cousins?" in: Genome biology, Vol. 3, Issue 9, pp. reviews3012, (2002) (PubMed).

Classon, Dyson: "p107 and p130: versatile proteins with interesting pockets." in: Experimental cell research, Vol. 264, Issue 1, pp. 135-47, (2001) (PubMed).

Yeung, Bell, Testa, Mayol, Baldi, Graña, Klinga-Levan, Knudson, Giordano: "The retinoblastoma-related gene, RB2, maps to human chromosome 16q12 and rat chromosome 19." in: Oncogene, Vol. 8, Issue 12, pp. 3465-8, (1993) (PubMed).

Aliases for p130 Antibodies

retinoblastoma-like 2 (p130) (RBL2) Antibodies
RB transcriptional corepressor like 2 (RBL2) Antibodies
related to retinoblastoma 2 (LOC541652) Antibodies
RB transcriptional corepressor like 2 (Rbl2) Antibodies
p130 Antibodies
P130 Antibodies
PRB2 Antibodies
Rb2 Antibodies
RBL2 Antibodies
RBR-2 Antibodies
RBR2 Antibodies
RRB2a Antibodies
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