P2RY12 antibody

Catalog No. ABIN5611346

Product Details anti-P2RY12 Antibody

Target: P2RY12 (Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This P2RY12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)

Purification: purified

Immunogen: Purified recombinant fragment of human P2RY12 (AA: extra mix) expressed in E. coli.

Clone: 1C2A9

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for P2RY12

Target: P2RY12 (Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))

Alternative Name: P2RY12 (P2RY12 Products)

Synonyms: 2900079B22Rik antibody, 4921504D23Rik antibody, P2Y12 antibody, ADPG-R antibody, BDPLT8 antibody, HORK3 antibody, P2T(AC) antibody, P2Y(12)R antibody, P2Y(AC) antibody, P2Y(ADP) antibody, P2Y(cyc) antibody, SP1999 antibody, P2y12 antibody, purinergic receptor P2Y, G-protein coupled 12 antibody, purinergic receptor P2Y12 antibody, P2ry12 antibody, P2RY12 antibody

Background:

Description: The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene.

Aliases: HORK3, P2Y12, ADPG-R, BDPLT8, SP1999, P2T(AC), P2Y(AC), P2Y(12)R, P2Y(ADP), P2Y(cyc)

Molecular Weight: 39.4 kDa

Gene ID: 64805

HGNC: 64805