Runt-Related Transcription Factor 1 (RUNX1) ELISA Kits

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. Additionally we are shipping RUNX1 Antibodies (284) and RUNX1 Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
RUNX1 12394 Q03347
RUNX1 861 Q01196
RUNX1 50662 Q63046
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Top RUNX1 ELISA Kits at antibodies-online.com

Showing 4 out of 14 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Rat 6.25 pg/mL 25-1600 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
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Human
  96 Tests Log in to see 1 to 2 Days
$898.33
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Human
  96 Tests Log in to see 2 to 3 Days
$480.00
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Human
  96 Tests Log in to see 6 Days
$642.86
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More ELISA Kits for RUNX1 Interaction Partners

Mouse (Murine) Runt-Related Transcription Factor 1 (RUNX1) interaction partners

  1. RUNX1 is essential for the development of the granular convoluted tubules in the submandibular glands; RUNX1 could also be involved in the membrane trafficking of the AQP5 (show AQP5 ELISA Kits) protein of the acinar cells in the SMG (show SNRPG ELISA Kits) in order to allow for the proper secretion of saliva (show RAG1AP1 ELISA Kits)

  2. High RUNX1 expression is associated with skin squamous cell carcinoma.

  3. deficiency alters the expression of a crucial subset of TAL1 (show TAL1 ELISA Kits)- and NOTCH1 (show NOTCH1 ELISA Kits)-regulated genes, including the MYB (show MYB ELISA Kits) and MYC (show MYC ELISA Kits) oncogenes, respectively.

  4. results demonstrate that RUNX1, when uncoupled from the requirement for cooperative ETS1 binding, is sufficient to drive long-range loop formation by the enhancer Ebeta, nucleosome clearance at its target promoters, and full transcriptional activation of the TCR beta recombination center

  5. hemogenic competency in recently specified endothelial progenitors is restrained through the active silencing of Runx1 expression.

  6. Leukaemogenesis by AML1-ETO (show RUNX1T1 ELISA Kits) requires enhanced C/D box snoRNA/RNP (show RNPC3 ELISA Kits) formation.

  7. In this study, we found upregulation of several hemostasis-related genes, including the thrombin (show F2 ELISA Kits)-activatable receptor PAR-1 (protease-activated receptor-1 (show F2R ELISA Kits)), in Runx1/Cbfb (show CBFB ELISA Kits)-deleted MLL (show MLL ELISA Kits)-AF9 (show MLLT3 ELISA Kits) cells. Similar to the effect of Runx1/Cbfb (show CBFB ELISA Kits) deletion, PAR-1 (show MARK2 ELISA Kits) overexpression induced CDKN1A/p21 (show CDKN1A ELISA Kits) expression and attenuated proliferation in MLL (show MLL ELISA Kits)-AF9 (show MLLT3 ELISA Kits) cells

  8. Immunohistochemical staining for RUNX1 showed reactivity in angiogenic tufts in the retina of mice with oxygen-induced retinopathy, suggesting that RUNX1 upregulation is a hallmark of aberrant retinal angiogenesis.

  9. The Runx1-persistent group is involved in transmitting mechanical and thermal information, whereas the Runx1-transient group transmits pruriceptive information. Such hierarchical control mechanisms may provide a developmental solution for the formation of sensory circuits that transmit distinct modalities.

  10. RUNX1 was expressed in both mesenchymal and epithelial compartments of the developing and postnatal lung. Increased respiratory distress, inflammation, and proinflammatory cytokines were observed in the Runx1-deleted mice after pulmonary LPS (show TLR4 ELISA Kits) exposure. RUNX1 deletion was associated with the activation of NF-kappaB (show NFKB1 ELISA Kits) in respiratory epithelial cells. RUNX1 was required for the suppression of NF-kappaB (show NFKB1 ELISA Kits) signaling pathway.

Human Runt-Related Transcription Factor 1 (RUNX1) interaction partners

  1. discussion of the role of RUNX1 in diseases caused by their mutations or deletions (review)

  2. Placental hematopoietic stem and progenitor cells likely arise from hematopoietic niches comprised RUNX1+ mesenchyme and vascular endothelium. Pregnancy complications that result in preterm birth differentially affect placental hematopoietic stem and progenitor cells localization and RUNX1 expression

  3. deficiency alters the expression of a crucial subset of TAL1 (show TAL1 ELISA Kits)- and NOTCH1 (show NOTCH1 ELISA Kits)-regulated genes, including the MYB (show MYB ELISA Kits) and MYC (show MYC ELISA Kits) oncogenes, respectively.

  4. Our findings strengthen previous data concerning RUNX1 mutations in acute myeloid leukemia (show BCL11A ELISA Kits) and support the notion that RUNX1 mutational status should be integrated into a diagnostic workup of acute myeloid leukemia (show BCL11A ELISA Kits).

  5. Heterozygous germ line mutations in the RUNX1 gene are responsible genetic events for FPD/AML.

  6. Data suggest that RUNX1 pays dual roles in normal female sexual development/maturation and tumorigenesis in female-related cancers; "alterations" in RUNX1, either mutations in RUNX1 gene or variations in expression of RUNX1, appear to be associated with breast, ovarian, uterine, and cervical neoplasms. [REVIEW]

  7. The E3 ubiquitin ligase STUB1 (show STUB1 ELISA Kits) is a negative regulator of both RUNX1 and RUNX1-RUNX1T1 (show RUNX1T1 ELISA Kits). Activation of STUB1 (show STUB1 ELISA Kits) could be a promising therapeutic strategy for RUNX1-RUNX1T1 (show RUNX1T1 ELISA Kits) leukemia.

  8. The clinical significance of ETV6 (show ETV6 ELISA Kits)-RUNX1.

  9. Deliver the necessary promotional drive for the progression of ETV6 (show ETV6 ELISA Kits)-RUNX1+ pre-leukaemic cells.

  10. High RUNX1 expression is associated with pancreatic cancer.

Zebrafish Runt-Related Transcription Factor 1 (RUNX1) interaction partners

  1. Our data suggest that runx1 and cbfb are required at 2 different steps during early hematopoietic stem cell development

  2. We propose that cohesin and CTCF (show CTCF ELISA Kits) have distinct functions in the regulation of runx1 during zebrafish embryogenesis.

  3. Morpholino knockdown of Myef2 (show MYEF2 ELISA Kits) or Runx1 in zebrafish results in reduced numbers of hematopoietic stem cells, suggesting that these two factors also interact in vivo to regulate hematopoiesis.

  4. Runx1 is induced by high Pu.1 level and in turn transrepresses pu.1 expression, thus constituting a negative feedback loop that fashions a favorable Pu.1 level required for balanced fate commitment to neutrophils versus macrophages.

  5. hematopoietic stem cell numbers depended on activity of the transcription factor Runx1, on blood flow, and on proper development of the dorsal aorta

  6. in zebrafish adult HSCs can be formed without an intact runx1.

  7. Zebrafish embryos lacking Rad21 (show RAD21 ELISA Kits), or cohesin subunit Smc3 (show SMC3 ELISA Kits), fail to express runx3 (show RUNX3 ELISA Kits) and lose hematopoietic runx1 expression in early embryonic development.

Xenopus laevis Runt-Related Transcription Factor 1 (RUNX1) interaction partners

  1. Xaml1/Runx1 is required for the specification of Rohon-Beard sensory neurons in Xenopus.

  2. ETV6-RUNX1 (TEL-AML1) fusion and hyperdiploidy (>50 chromosomes) are favorable genetic features in childhood acute lymphoblastic leukemia (ALL).

  3. reveal a shift in Runx2 (show RUNX2 ELISA Kits) function protein during vertebrate evolution towards its exclusive roles in cartilage hypertrophy and bone differentiation within the amniote lineage

RUNX1 Antigen Profile

Antigen Summary

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with RUNX1

  • runt-related transcription factor 1 (RUNX1) antibody
  • runt-related transcription factor (runt) antibody
  • runt related transcription factor 1 (Runx1) antibody
  • runt-related transcription factor 1 (runx1) antibody
  • runt-related transcription factor 1 (Runx1) antibody
  • AI462102 antibody
  • aml antibody
  • aml-1 antibody
  • Aml1 antibody
  • aml1-evi-1 antibody
  • amlcr1 antibody
  • cbfa2 antibody
  • evi-1 antibody
  • Pebp2a2 antibody
  • pebp2ab antibody
  • Pebpa2b antibody
  • Runx-1 antibody
  • runx1 antibody
  • runxa antibody
  • XAML antibody
  • Xaml1 antibody

Protein level used designations for RUNX1

runt-related transcription factor 1 , runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) , runt-related transcription factor , runt protein , CBF-alpha-2 , PEA2-alpha B , PEBP2-alpha B , SL3-3 enhancer factor 1 alpha B subunit , SL3/AKV core-binding factor alpha B subunit , acute myeloid leukemia 1 protein , core binding factor alpha 2 , core-binding factor subunit alpha-2 , oncogene AML-1 , polyomavirus enhancer-binding protein 2 alpha B subunit , runt domain, alpha subunit 2 , AML1-EVI-1 fusion protein , core-binding factor, runt domain, alpha subunit 2 , aml1 , runt-related transcription factor a , runx1a , Acute myeloid leukemia 1 protein , Core-binding factor subunit alpha-2 , aml1 oncogene , ch-runtB2 , acute myeloid leukemia 1 , factor, runt domain, alpha subunit 2 , core-binding factor runt domain alpha subunit 2 (acute myeloid leukemia 1 oncogene) , runt related transcription factor 1

GENE ID SPECIES
473981 Pan troglodytes
100302713 Saccoglossus kowalevskii
12394 Mus musculus
861 Homo sapiens
58126 Danio rerio
379657 Xenopus laevis
396152 Gallus gallus
487746 Canis lupus familiaris
529631 Bos taurus
50662 Rattus norvegicus
100512633 Sus scrofa
100724149 Cavia porcellus
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