Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

RUNX1 Products

(Runt-Related Transcription Factor 1 (RUNX1))
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured RUNX1 Categories

RUNX1 Antibodies

High quality antibodies with extensive validation data.

RUNX1 ELISA Kits

Reliable ELISA kits for a wide range of species.

RUNX1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RUNX1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application FACS, IF, IHC, ELISA, WB
Validations
  • (6)
Cat. No. ABIN3028995
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application IF, IHC (p), ELISA, WB
Validations
  • (2)
  • (5)
Cat. No. ABIN514054
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC (p), WB
Validations
  • (1)
  • (4)
Cat. No. ABIN3043318
Quantity 100 μg
Datasheet Datasheet

Recommended RUNX1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380155
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380156
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380825
Quantity 2 x 96 tests
Datasheet Datasheet

Recommended RUNX1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (2)
Cat. No. ABIN2731253
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3095157
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3134816
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our RUNX1 products

Hong, He, Li, Chu, Pu, Tong, Joshi, Tang, Li: "Runt-related transcription factor 1 promotes apoptosis and inhibits neuroblastoma progression in vitro and in vivo." in: Journal of experimental & clinical cancer research : CR, Vol. 39, Issue 1, pp. 52, (2020) (PubMed).

Illendula, Gilmour, Grembecka, Tirumala, Boulton, Kuntimaddi, Schmidt, Wang, Pulikkan, Zong, Parlak, Kuscu, Pickin, Zhou, Gao, Mishra, Adli, Castilla, Rajewski, Janes, Guzman, Bonifer, Bushweller: "Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers." in: EBioMedicine, Vol. 8, pp. 117-31, (2016) (PubMed).

Miao, Zhao, Zhao, Wang, Liu, Ma, Xue: "MiR-18a increased the permeability of BTB via RUNX1 mediated down-regulation of ZO-1, occludin and claudin-5." in: Cellular signalling, Vol. 27, Issue 1, pp. 156-67, (2015) (PubMed).

Dobson, Taipaleenmäki, Hu, Hong, van Wijnen, Stein, Stein, Lian, Pratap: "hsa-mir-30c promotes the invasive phenotype of metastatic breast cancer cells by targeting NOV/CCN3." in: Cancer cell international, Vol. 14, pp. 73, (2014) (PubMed).

Ferrari, Mohammed, Nixon, Mason, Mallon, McMillan, Morris, Cameron, Edwards, Blyth: "Expression of RUNX1 correlates with poor patient prognosis in triple negative breast cancer." in: PLoS ONE, Vol. 9, Issue 6, pp. e100759, (2014) (PubMed).

Mochin, Underwood, Cooper, McLenithan, Pierce, Nalvarte, Arbiser, Karlsson, Moise, Moskovitz, Passaniti: "Hyperglycemia and redox status regulate RUNX2 DNA-binding and an angiogenic phenotype in endothelial cells." in: Microvascular research, Vol. 97, pp. 55-64, (2014) (PubMed).

Du, Li, Zhong, Fan, Qiao, He, Fu, Wang, Ye: "Brain death induces the alteration of liver protein expression profiles in rabbits." in: International journal of molecular medicine, Vol. 34, Issue 2, pp. 578-84, (2014) (PubMed).

Keita, Bachvarova, Morin, Plante, Gregoire, Renaud, Sebastianelli, Trinh, Bachvarov: "The RUNX1 transcription factor is expressed in serous epithelial ovarian carcinoma and contributes to cell proliferation, migration and invasion." in: Cell cycle (Georgetown, Tex.), Vol. 12, Issue 6, pp. 972-86, (2013) (PubMed).

Niu, Kondo, Nakazawa, Oishi, Kawasaki, Mochizuki, Yamane, Katoh: "Transcription factor Runx2 is a regulator of epithelial-mesenchymal transition and invasion in thyroid carcinomas." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 92, Issue 8, pp. 1181-90, (2012) (PubMed).

Taniuchi, Osato, Ito: "Runx1: no longer just for leukemia." in: The EMBO journal, Vol. 31, Issue 21, pp. 4098-9, (2012) (PubMed).

Synonyms and alternative names related to RUNX1

uncharacterized LOC473981 (LOC473981), runt-related transcription factor (runt), runt related transcription factor 1 (Runx1), runt related transcription factor 1 (RUNX1), runt-related transcription factor 1 (runx1), runt related transcription factor 1 L homeolog (runx1.L), runt-related transcription factor 1 (RUNX1), runt-related transcription factor 1 (Runx1), AI462102, aml, aml-1, AML1, aml1, Aml1, AML1-EVI-1, aml1-evi-1, AMLCR1, amlcr1, Cbfa2, CBFA2, cbfa2, EVI-1, evi-1, Pebp2a2, PEBP2aB, pebp2ab, Pebpa2b, Runx-1, RUNX1, runx1, runxa, XAML, Xaml1

Protein level used designations for RUNX1

  • runt-related transcription factor 1
  • runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene)
  • runt-related transcription factor
  • runt protein
  • CBF-alpha-2
  • PEA2-alpha B
  • PEBP2-alpha B
  • SL3-3 enhancer factor 1 alpha B subunit
  • SL3/AKV core-binding factor alpha B subunit
  • acute myeloid leukemia 1 protein
  • core binding factor alpha 2
  • core-binding factor subunit alpha-2
  • oncogene AML-1
  • polyomavirus enhancer-binding protein 2 alpha B subunit
  • runt domain, alpha subunit 2
  • AML1-EVI-1 fusion protein
  • core-binding factor, runt domain, alpha subunit 2
  • aml1
  • runt-related transcription factor a
  • runx1a
  • Acute myeloid leukemia 1 protein
  • Core-binding factor subunit alpha-2
  • aml1 oncogene
  • ch-runtB2
  • acute myeloid leukemia 1
  • factor, runt domain, alpha subunit 2
  • core-binding factor runt domain alpha subunit 2 (acute myeloid leukemia 1 oncogene)
  • runt related transcription factor 1
You are here:
Support