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Synuclein, beta Proteins (SNCB)

The protein encoded by SNCB is highly homologous to alpha-synuclein. Additionally we are shipping beta Synuclein Antibodies (82) and beta Synuclein Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SNCB 6620 Q16143
SNCB 104069 Q91ZZ3
SNCB 113893 Q63754
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Top beta Synuclein Proteins at

Showing 10 out of 15 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 7 to 8 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 10 to 12 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   200 μg Log in to see 3 to 4 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 6 to 11 Days
Human Un-conjugated   2 μg Log in to see 6 Days

SNCB Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
Mouse (Murine)

Rat (Rattus)

Top referenced beta Synuclein Proteins

  1. Human beta Synuclein Protein expressed in Escherichia coli (E. coli) - ABIN666819 : Hashimoto, Rockenstein, Mante, Mallory, Masliah: beta-Synuclein inhibits alpha-synuclein aggregation: a possible role as an anti-parkinsonian factor. in Neuron 2001 (PubMed)
    Show all 3 references for ABIN666819

More Proteins for Synuclein, beta (SNCB) Interaction Partners

Human Synuclein, beta (SNCB) interaction partners

  1. loss of inhibitory C-terminal conformations in disease associated P123H beta-synuclein

  2. beta-Synuclein expression was locally concentrated and rather modest, but nevertheless changed its effect on amyloid precursor protein (show APP Proteins) expression and plaque load in a time- and concentration-dependent manner.

  3. The differing aggregation propensities of alpha-synuclein and beta-synuclein are associated with differences in the degree of residual structure in the C-terminus coupled to the shorter separation between the N- and C-termini in beta-synuclein.

  4. Beta-synuclein protects against isoaspartate accumulation in alpha-synuclein.

  5. In vivo cross-linking reveals principally oligomeric forms of alpha-synuclein and beta-synuclein in neurons and non-neural cells

  6. Thermodynamic studies in conjunction with EPR (show EREG Proteins) confirm that alpha-synuclein, beta-synuclein, and gamma-synuclein (show SNCG Proteins) bind copper(II) in a high affinity 1:1 stoichiometry.

  7. Data provide evidence for the role of beta-synuclein minor transcript variants in the development of complex diseases and provide new insights into the pathogenesis of Lewy body diseases.

  8. This study suggested that the pathogenesis of dementia in Parkinson disease, indicating that differential sncb expression in the caudate nucleus may represent one of the molecular mechanisms involved in these complex diseases.

  9. Despite both synucleins sharing considerable sequence homology, the level of carboxy-terminal Src kinase-homologous kinase (CHK) phosphorylation of beta-synuclein is significantly higher than that of alpha-synuclein.

  10. Transcriptional regulation of the beta-synuclein 5'-promoter metal response element by metal transcription factor-1.

Mouse (Murine) Synuclein, beta (SNCB) interaction partners

  1. Immunoblot analysis of beta-synuclein and Akt (show AKT1 Proteins) levels in the mice reveals selective increases in beta-synuclein and phosphorylated Akt (show AKT1 Proteins) levels in ventral midbrain

  2. Beta-synuclein decreased formation of Lewy bodies by 40%, and prevented functional deficits associated with overexpression of alpha-synuclein. This is a preliminary in vivo proof of antiaggregatory function of beta-synuclein.

  3. Accelerated accumulation of beta-synuclein is found in axonal spheroids of gracile axonal dystrophy mice, which do not express ubiquitin carboxyl-terminal hydrolase L1.

  4. beta-synuclein knockout mice show that synucleins are not essential components of the basic machinery for neurotransmitter release but may contribute to the long-term regulation and/or maintenance of presynaptic function.

  5. Developmentally, gamma-synuclein (show SNCG Proteins) can be seen in the region of the outer hair cells by E19, while alpha- and beta-synuclein do not clearly appear there until approximately P10 (show NUTF2 Proteins)

beta Synuclein (SNCB) Protein Profile

Protein Summary

The protein encoded by this gene is highly homologous to alpha-synuclein. These proteins are abundantly expressed in the brain and putatively inhibit phospholipase D2 selectively. The encoded protein, which may play a role in neuronal plasticity, is abundant in neurofibrillary lesions of patients with Alzheimer disease. This protein has been shown to be highly expressed in the substantia nigra of the brain, a region of neuronal degeneration in patients with Parkinson disease\; however, no direct relation to Parkinson disease has been established. Two transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with Synuclein, beta Proteins (SNCB)

  • synuclein, beta (SNCB)
  • synuclein, beta (Sncb)
  • AI838531 protein
  • betaSYN protein

Protein level used designations for Synuclein, beta Proteins (SNCB)

beta-synuclein , PNP 14 , phosphoneuroprotein 14

100127169 Sus scrofa
6620 Homo sapiens
104069 Mus musculus
113893 Rattus norvegicus
508421 Bos taurus
479279 Canis lupus familiaris
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