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beta Synuclein Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

SNCB Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2715251
  • Target See all beta Synuclein (SNCB) Proteins
    beta Synuclein (SNCB) (Synuclein, beta (SNCB))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 5
    • 1
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This beta Synuclein protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Beta-Synuclein / SCNB (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product SNCB Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    beta Synuclein (SNCB) (Synuclein, beta (SNCB))
    Alternative Name
    beta-Synuclein,scnb (SNCB Products)
    Synonyms
    AI838531 Protein, betaSYN Protein, zgc:66343 Protein, sncb Protein, MGC75784 Protein, LOC619281 Protein, SNCB Protein, syub Protein, synuclein beta Protein, synuclein, beta Protein, synuclein beta L homeolog Protein, Beta-synuclein Protein, SNCB Protein, Sncb Protein, sncb Protein, sncb.L Protein, syub Protein
    Background
    Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease. [UniProtKB/Swiss-Prot Function]
    Molecular Weight
    14.1 kDa
    NCBI Accession
    NP_001001502
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