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beta Synuclein Products

(Synuclein, beta (SNCB))

Categories

The protein encoded by this gene is highly homologous to alpha-synuclein. These proteins are abundantly expressed in the brain and putatively inhibit phospholipase D2 selectively. The encoded protein, which may play a role in neuronal plasticity, is abundant in neurofibrillary lesions of patients with Alzheimer disease. This protein has been shown to be highly expressed in the substantia nigra of the brain, a region of neuronal degeneration in patients with Parkinson disease\; however, no direct relation to Parkinson disease has been established. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured beta Synuclein Categories

beta Synuclein Antibodies

High quality antibodies with extensive validation data.

beta Synuclein ELISA Kits

Reliable ELISA kits for a wide range of species.

beta Synuclein Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended beta Synuclein Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7182802
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
Cat. No. ABIN6265408
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN652024
Quantity 400 μL
Datasheet Datasheet

Recommended beta Synuclein ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Dog, Human, Mouse, Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1110851
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4884595
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6384291
Quantity 96 tests
Datasheet Datasheet

Recommended beta Synuclein Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125302
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN934879
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320782
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our beta Synuclein products

Irvine, El-Agnaf, Shankar, Walsh: "Protein aggregation in the brain: the molecular basis for Alzheimer's and Parkinson's diseases." in: Molecular medicine (Cambridge, Mass.), Vol. 14, Issue 7-8, pp. 451-64, (2008) (PubMed).

Wakabayashi, Tanji, Mori, Takahashi: "The Lewy body in Parkinson's disease: molecules implicated in the formation and degradation of alpha-synuclein aggregates." in: Neuropathology : official journal of the Japanese Society of Neuropathology, Vol. 27, Issue 5, pp. 494-506, (2007) (PubMed).

Hashimoto, Bar-On, Ho, Takenouchi, Rockenstein, Crews, Masliah: "Beta-synuclein regulates Akt activity in neuronal cells. A possible mechanism for neuroprotection in Parkinson's disease." in: The Journal of biological chemistry, Vol. 279, Issue 22, pp. 23622-9, (2004) (PubMed).

George: "The synucleins." in: Genome biology, Vol. 3, Issue 1, pp. REVIEWS3002, (2002) (PubMed).

Giasson, Duda, Forman, Lee, Trojanowski: "Prominent perikaryal expression of alpha- and beta-synuclein in neurons of dorsal root ganglion and in medullary neurons." in: Experimental neurology, Vol. 172, Issue 2, pp. 354-62, (2001) (PubMed).

Bruening, Giasson, Klein-Szanto, Lee, Trojanowski, Godwin: "Synucleins are expressed in the majority of breast and ovarian carcinomas and in preneoplastic lesions of the ovary." in: Cancer, Vol. 88, Issue 9, pp. 2154-63, (2000) (PubMed).

Synonyms and alternative names related to beta Synuclein

synuclein beta (SNCB), synuclein, beta (Sncb), synuclein, beta (sncb), synuclein beta (sncb), synuclein beta L homeolog (sncb.L), Beta-synuclein (syub), AI838531, betaSYN, LOC619281, MGC75784, sncb, SNCB, syub, zgc:66343

Protein level used designations for beta Synuclein

  • beta-synuclein
  • PNP 14
  • phosphoneuroprotein 14
  • zSyn-&beta
  • zSynC
  • synuclein, beta
  • putative beta-synuclein variant 1
  • Beta-synuclein
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