anti-Tropomyosin 3 (TPM3) Antibodies

TPM3 encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Additionally we are shipping TPM3 Proteins (16) and TPM3 Kits (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TPM3 7170 P06753
TPM3 117557 Q63610
TPM3 59069 P21107
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Top anti-TPM3 Antibodies at

Showing 10 out of 36 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-TPM3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: THP-1 cell lysate 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: tropomyosin-3 Antibody  - Staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes. Western Blot: tropomyosin-3 Antibody  - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II. 0.1 mL Log in to see 10 to 13 Days
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to TPM3 on formalin-fixed paraffin-embedded human smooth muscle. [antibody concentration 3 ug/ml] Detection limit for recombinant GST tagged TPM3 is 0.1 ng/ml as a capture antibody. 100 μg Log in to see 11 to 12 Days
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
Human Mouse Un-conjugated IHC (p), ELISA, WB Anti-TPM3 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1104792 dilution 20 ug/ml. 50 μg Log in to see 7 to 9 Days
Human Mouse Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IF, IHC, WB Western blot analysis of extracts of various tissues, using TPM3 antibody. 100 μL Log in to see 16 Days
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of Tropomyosin 3 staining in Hela cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary a Immunohistochemical analysis of Tropomyosin 3 staining in mouse heart formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated wi 200 μL Log in to see 13 to 14 Days
Mouse Rabbit Un-conjugated IHC, WB Immunofluorescence analysis of HeLa cell using TPM3 antibody. Blue: DAPI for nuclear staining. 100 μL Log in to see 13 to 14 Days

TPM3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Rat (Rattus)

Mouse (Murine)
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Top referenced anti-TPM3 Antibodies

  1. Cow (Bovine) Polyclonal TPM3 Primary Antibody for WB - ABIN2776646 : Ramsey, Clarke, Roberts, Sullivan, Johnson, Liu: An economic evaluation of atorvastatin for primary prevention of cardiovascular events in type 2 diabetes. in PharmacoEconomics 2008 (PubMed)
    Show all 2 references for 2776646

  2. Human Monoclonal TPM3 Primary Antibody for IHC (p), ELISA - ABIN521063 : Doukhanine, Gavino, Haines, Almazan, Richard: The QKI-6 RNA binding protein regulates actin-interacting protein-1 mRNA stability during oligodendrocyte differentiation. in Molecular biology of the cell 2010 (PubMed)

  3. Human Polyclonal TPM3 Primary Antibody for IHC, IHC (p) - ABIN4362650 : Singleton, Rouhi, Zois, Haider, Li, Kessler, Cao, Harris: Hypoxic regulation of RIOK3 is a major mechanism for cancer cell invasion and metastasis. in Oncogene 2014 (PubMed)

More Antibodies against TPM3 Interaction Partners

Human Tropomyosin 3 (TPM3) interaction partners

  1. expression levels of tropomyosin 3 (TPM3) were higher in stage III ESCC tissue compared with stage I (P<0.05). The findings of the present study identified twelve proteins, which are closely associated with ESCC invasion and metastasis, apoptosis and cell signal transduction.

  2. Dominant mutations in TPM3, encoding alpha-tropomyosinslow, cause a congenital myopathy characterized by generalized muscle weakness. Here, we used a multidisciplinary approach to investigate the mechanism of muscle dysfunction in 12 TPM3-myopathy patients.

  3. This work expands the phenotypic spectrum of TPM3-related disease and provides insights into the pathophysiological mechanisms of the actin-tropomyosin (show TPM2 Antibodies) complex

  4. Western blot showed phosphorylation of ALK (show ALK Antibodies), ERK1/2 (show MAPK1/3 Antibodies), and STAT3 (show STAT3 Antibodies) in cells transfected with TPM3-ALK (show ALK Antibodies). Coiled-coil structure of TPM3 contributes to the transforming ability of the TPM3-ALK (show ALK Antibodies) fusion protein, and longer TPM3 region leads to higher dimer formation.

  5. Patients with TPM2 (show TPM2 Antibodies) mutations tended to present with milder symptoms than those with TPM3 mutations, DA being present only in the TPM2 (show TPM2 Antibodies) group.

  6. in a cohort of 94 patients with congenital myopathy, 2 related female patients and 2 sporadic male patients were found to carry mutations in TPM2 (show TPM2 Antibodies) and TPM3 genes respectively; clinical presentation and muscle morphological findings differed in the patients

  7. DATA show that tropomyosin 3 protein (TPM3) plays a critical role in the progression of gliomas.

  8. study reports on a three-generation family with cap myopathy caused by a novel heterozygous mutation in TPM3

  9. In addition to CLIC1 (show CLIC1 Antibodies) and TPM1 (show TPM1 Antibodies), which were the proteins initially discovered in a xenograft mouse model, CLIC4 (show CLIC4 Antibodies), TPM2 (show TPM2 Antibodies), TPM3, and TPM4 (show TPM4 Antibodies) were present in ovarian cancer patient sera at significantly elevated levels compared with controls.

  10. TPM3-R167H mutations decreased cooperative thin filament activation in combination with reductions in the myosin cross-bridge number and force production.

Mouse (Murine) Tropomyosin 3 (TPM3) interaction partners

  1. Tpm3 plays crucial roles in maintaining cortical actin integrity and asymmetric cell division during oocyte maturation, and that dynamic regulation of cortical actin by Tpm3 is critical to ensure proper polar body protrusion.

  2. TMBr-3 and TM5NM1 modestly affected actin assembly kinetics, in an opposite manner.

  3. Tropomyosin (show TPM2 Antibodies) regulates cell migration during skin wound healing.

  4. Data conclude that exon 9d-containing isoforms are not essential for survival of neuronal cells and that isoform choice from the gamma-Tm gene is flexible in the brain

  5. Reduced expression of Tpm3, sarcomere genes and Lrtm1 in the diaphragm of mice with diaphragmatic defects.

  6. Tropomyosin 3 expression leads to hypercontractility and attenuates myofilament length-dependent Ca(2 (show CA2 Antibodies)+) activation.

  7. tropomyosin (show TPM2 Antibodies) isoforms regulate neuronal size and shape

  8. results indicate that a Tm5NM1-defined actin cytoskeleton is required for the normal excitation-contraction coupling in skeletal muscle

TPM3 Antigen Profile

Protein Summary

This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-Tropomyosin 3 (TPM3) Antibodies

  • tropomyosin 3 (TPM3) antibody
  • tropomyosin 3 (tpm3) antibody
  • tropomyosin 3 (Tpm3) antibody
  • tropomyosin 3, gamma (Tpm3) antibody
  • CAPM1 antibody
  • cb674 antibody
  • CFTD antibody
  • fa17b11 antibody
  • fb83b01 antibody
  • fk41e01 antibody
  • gamma-TM antibody
  • hm:zeh0298 antibody
  • hscp30 antibody
  • hTM30nm antibody
  • hTMnm antibody
  • NEM1 antibody
  • OK/SW-cl.5 antibody
  • TM-5 antibody
  • TM3 antibody
  • TM5 antibody
  • Tm5NM antibody
  • TM30 antibody
  • TM30nm antibody
  • Tpm-5 antibody
  • TPM3 antibody
  • Tpm5 antibody
  • TPMsk3 antibody
  • TRK antibody
  • Trop-5 antibody
  • wu:fa17b11 antibody
  • wu:fb83b01 antibody
  • wu:fk41e01 antibody
  • zeh0298 antibody
  • zgc:77592 antibody

Protein level used designations for anti-Tropomyosin 3 (TPM3) Antibodies

tropomyosin 3 , tropomyosin alpha-3 chain , alpha-tropomyosin, slow skeletal , cytoskeletal tropomyosin TM30 , heat-stable cytoskeletal protein 30 kDa , tropomyosin gamma , tropomyosin-5 , gamma-tropomyosin , tropomyosin-3 , nonmuscle tropomyosin 5 , tropomyosin 3, gamma , tropomyosin non-muscle , skalphaTM.2 , tropomyosin 5

458000 Pan troglodytes
480137 Canis lupus familiaris
484695 Canis lupus familiaris
100174017 Pongo abelii
373076 Danio rerio
7170 Homo sapiens
497019 Bos taurus
117557 Rattus norvegicus
414388 Sus scrofa
59069 Mus musculus
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