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TPMT Antibodies

(Thiopurine S-Methyltransferase (TPMT))
This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q. [provided by RefSeq, Jul 2008].
TPMT antibody  (AA 26-227) TPMT antibody  (AA 26-227) TPMT antibody (AA 26-227) (ABIN7435148)

TPMT Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

TPMT antibody TPMT antibody TPMT antibody (ABIN1501480)

TPMT Reactivity: Human, Dog WB, IHC, IHC (p), FACS Host: Mouse Monoclonal 4C1 unconjugated

TPMT antibody  (AA 1-245) TPMT antibody  (AA 1-245) TPMT antibody (AA 1-245) (ABIN563239)

TPMT Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 1B5 unconjugated

TPMT Antibodies by Reactivity

Find TPMT Antibodies for a variety of species such as anti-Human TPMT, anti-Mouse TPMT, anti-Rat TPMT. The species listed below are among those available. Click on a link to go to the corresponding products.

TPMT Antibodies by Application

Find TPMT Antibodies validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

TPMT Antibodies by Host

Find TPMT Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

TPMT Antibodies by Binding Specificity

Find TPMT Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

TPMT Antibodies by Clonality

Find available monoclonal or polyclonal TPMT Antibodies. Click on a link to go to the corresponding products.

TPMT Antibodies by Clone

Find TPMT Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

TPMT Antibodies by Conjugate

Find TPMT Antibodies with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular TPMT Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7435148
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Human
Application WB, IHC, IHC (p), FACS
Validations
  • (6)
Cat. No. ABIN1501480
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (2)
  • (5)
Cat. No. ABIN563239
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IP
Validations
  • (3)
Cat. No. ABIN7171992
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN3021279
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN6265692
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF, IC
Validations
  • (2)
Cat. No. ABIN7305900
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, EIA
Validations
  • (2)
Cat. No. ABIN781549
Quantity 0.1 mL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7252816
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7246526
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IHC (p)
Validations
  • (1)
Cat. No. ABIN1957182
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IHC (p)
Validations
  • (1)
Cat. No. ABIN1958290
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IHC (p)
Validations
  • (1)
Cat. No. ABIN1955947
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Pig
Application WB
Validations
  • (1)
Cat. No. ABIN6748459
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN933769
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our TPMT Antibodies

Hayashi, Naoi, Nakagawa, Nishikawa, Fukuda, Imajoh-Ohmi, Kondo, Kubo, Yabuki, Hattori, Hirouchi, Sugiyama: "Sorting nexin 27 interacts with multidrug resistance-associated protein 4 (MRP4) and mediates internalization of MRP4." in: The Journal of biological chemistry, Vol. 287, Issue 18, pp. 15054-65, (2012) (PubMed).

Milek, Karas Kuzelicki, Smid, Mlinaric-Rascan: "S-adenosylmethionine regulates thiopurine methyltransferase activity and decreases 6-mercaptopurine cytotoxicity in MOLT lymphoblasts." in: Biochemical pharmacology, Vol. 77, Issue 12, pp. 1845-53, (2009) (PubMed).

Egle, Milek, Mlinaric-Rascan, Fahr, Kristl: "A novel gene delivery system for stable transfection of thiopurine-S-methyltransferase gene in versatile cell types." in: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V, Vol. 69, Issue 1, pp. 23-30, (2008) (PubMed).

Wang, Nguyen, McLaughlin, Sikkink, Ramirez-Alvarado, Weinshilboum: "Human thiopurine S-methyltransferase pharmacogenetics: variant allozyme misfolding and aggresome formation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 26, pp. 9394-9, (2005) (PubMed).

Martin, Trouche, Hagemeier, Sørensen, La Thangue, Kouzarides: "Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein." in: Nature, Vol. 375, Issue 6533, pp. 691-4, (1995) (PubMed).

Aliases for TPMT Antibodies

thiopurine S-methyltransferase L homeolog (tpmt.L) Antibodies
thiopurine S-methyltransferase, tandem duplicate 2 (tpmt.2) Antibodies
thiopurine S-methyltransferase TpmT (tpmT) Antibodies
thiopurine S-methyltransferase (MCA0794) Antibodies
thiopurine S-methyltransferase (Pnap_4948) Antibodies
thiopurine S-methyltransferase (Hhal_1383) Antibodies
thiopurine S-methyltransferase (TK90_1044) Antibodies
thiopurine S-methyltransferase (Slit_1144) Antibodies
thiopurine S-methyltransferase (Tint_0842) Antibodies
Thiopurine S-methyltransferase (Fbal_3334) Antibodies
thiopurine S-methyltransferase (Celly_3188) Antibodies
thiopurine S-methyltransferase (Weevi_1737) Antibodies
Thiopurine S-methyltransferase (Psefu_2696) Antibodies
Thiopurine S-methyltransferase (Metme_3860) Antibodies
thiopurine methyltransferase (Tpmt) Antibodies
thiopurine S-methyltransferase (TPMT) Antibodies
thiopurine S-methyltransferase (Tpmt) Antibodies
AW106912 Antibodies
MGC84277 Antibodies
NHLRC1 Antibodies
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