TPM3 antibody (AA 1-284)

Catalog No. ABIN3021721

This Rabbit Polyclonal antibody specifically detects TPM3 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for TPM3 antibody (AA 1-284) (ABIN3021721)

Target: TPM3 (Tropomyosin 3 (TPM3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPM3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-TPM3 Antibody

Binding Specificity: AA 1-284

Sequence: MMEAIKKKMQ MLKLDKENAL DRAEQAEAEQ KQAEERSKQL EDELAAMQKK LKGTEDELDK YSEALKDAQE KLELAEKKAA DAEAEVASLN RRIQLVEEEL DRAQERLATA LQKLEEAEKA ADESERGMKV IENRALKDEE KMELQEIQLK EAKHIAEEAD RKYEEVARKL VIIEGDLERT EERAELAESK CSELEEELKN VTNNLKSLEA QAEKYSQKED KYEEEIKILT DKLKEAETRA EFAERSVAKL EKTIDDLEDE LYAQKLKYKA ISEELDHALN DMTS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-284 of human TPM3 (NP_689476.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TPM3

Target: TPM3 (Tropomyosin 3 (TPM3))

Alternative Name: TPM3

Background: This gene encodes a member of the tropomyosin family of actin-binding proteins. Tropomyosins are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy and other muscle disorders. This locus is involved in translocations with other loci, including anaplastic lymphoma receptor tyrosine kinase (ALK) and neurotrophic tyrosine kinase receptor type 1 (NTRK1), which result in the formation of fusion proteins that act as oncogenes. There are numerous pseudogenes for this gene on different chromosomes. Alternative splicing results in multiple transcript variants.,TPM3,CAPM1,CFTD,HEL-189,HEL-S-82p,NEM1,OK/SW-cl.5,TM-5,TM3,TM30,TM30nm,TM5,TPMsk3,TRK,hscp30,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Actins,TPM3

Molecular Weight: 18 kDa/28 kDa/29 kDa/32 kDa

Gene ID: 7170

UniProt: P06753