Ubiquitin Specific Peptidase 25 Proteins (USP25)

Ubiquitin (MIM 191339) is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response. Additionally we are shipping USP25 Antibodies (61) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
USP25 29761 Q9UHP3
Rat USP25 USP25 304150  
Mouse USP25 USP25 30940 P57080
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Top USP25 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
HOST_Insect cells (Sf21) Human His tag   50 μg Log in to see 5 to 8 Days

USP25 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,

More Proteins for Ubiquitin Specific Peptidase 25 (USP25) Interaction Partners

Human Ubiquitin Specific Peptidase 25 (USP25) interaction partners

  1. Results suggest inhibition of Usp25's catalytic activity upon the non-covalent binding of SUMO2 to the Usp25 SUMO-interacting motif, and found that SUMO2 can competitively block the interaction between the Usp25 ubiquitin-binding region and its ubiquitin substrates.

  2. We detected SNPs at USP25 with associations of genome-wide significance for Inflammatory Bowel Disease.

  3. REM (show REM1 Proteins) Sleep Behavior Disorder patients with homozygous USP25 rs2823357 progressed to synucleinopathies faster than others.

  4. Findings suggest that ubiquitin-specific protease 25 (USP25) as a VRK2 (show VRK2 Proteins) substrate that acts on TRiC (show MARVELD2 Proteins) deubiquitination.

  5. These findings indicate that miR (show MLXIP Proteins)-200c exerts tumor-suppressive effects for NSCLC through the suppression of USP25 expression and suggests a new therapeutic application of miR (show MLXIP Proteins)-200c in the treatment of NSCLC.

  6. USP25 is a novel deubiquitinating enzyme negatively regulating virus-induced interferon-beta (show IFNB1 Proteins) production.

  7. a model where USP25 counteracts ubiquitination of ERAD substrates by the ubiquitin ligase HRD1 (show SYVN1 Proteins), rescuing them from degradation by the proteasome.

  8. Studies indicate that DUBs recycle ubiquitin by processing polyubiquitin chains to generate free ubiquitin, and can be regulated by ubiquitination or phosphorylation.

  9. the second SH2 domain of SYK (show SYK Proteins) physically interacts with a tyrosine-rich, C-terminal region of USP25 independently of tyrosine phosphorylation

  10. downregulation of USP25 gene in human lung cancer

Mouse (Murine) Ubiquitin Specific Peptidase 25 (USP25) interaction partners

  1. IRF7 (show IRF7 Proteins) directly binds to the two conserved IRF (show TRIM63 Proteins) binding sites on the USP25 promoter to drive transcription of Usp25.

  2. Data show that the degradation of TNF receptor-associated factor 3 (TRAF3 (show TRAF3 Proteins)) and TNF (show TNF Proteins) receptor-associated Ffactor 6 (TRAF6 (show TRAF6 Proteins)) was accelerated in ubiquitin-specific protease 25 knockout (USP25-/-) cells after viral infection.

  3. inhibiting the degradation of TRAF3 (show TRAF3 Proteins) during TLR4 (show TLR4 Proteins) activation, USP25 enables a balanced innate immune response.

  4. USP25 is a deubiquitinating enzyme (DUB) that negatively regulates IL-17 (show IL17A Proteins)-triggered signaling.

USP25 Protein Profile

Protein Summary

Ubiquitin (MIM 191339) is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response. Ubiquitin is released from degraded proteins by disassembly of the polyubiquitin chains, which is mediated by ubiquitin-specific proteases (USPs), such as USP25 (Valero et al., 1999

Gene names and symbols associated with USP25

  • ubiquitin specific peptidase 25 (USP25)
  • universal stress protein (usp25)
  • ubiquitin specific protease 25 (usp25)
  • ubiquitin specific peptidase 25 (usp25)
  • ubiquitin specific peptidase 25 (LOC100229974)
  • ubiquitin specific peptidase 25 (Usp25)
  • MGC81666 protein
  • USP21 protein
  • usp25 protein
  • wu:fi33c05 protein
  • wu:fo67e06 protein
  • wu:fp97a04 protein
  • zgc:55791 protein

Protein level used designations for USP25

ubiquitin specific peptidase 25 , ubiquitin carboxyl-terminal hydrolase 25-like , universal stress protein , ubiquitin carboxyl-terminal hydrolase 25 , ubiquitin specific protease 25 , USP on chromosome 21 , deubiquitinating enzyme 25 , ubiquitin thioesterase 25 , ubiquitin thiolesterase 25 , ubiquitin-specific processing protease 25 , ubiquitin-specific-processing protease 25 , mUSP25

100458885 Pongo abelii
478387 Canis lupus familiaris
524531 Bos taurus
716923 Macaca mulatta
3127262 Haloarcula marismortui ATCC 43049
100083895 Ornithorhynchus anatinus
100348335 Oryctolagus cuniculus
100393986 Callithrix jacchus
406790 Danio rerio
418471 Gallus gallus
446581 Xenopus laevis
473918 Pan troglodytes
733977 Xenopus (Silurana) tropicalis
100229974 Taeniopygia guttata
100546482 Meleagris gallopavo
100628105 Sus scrofa
29761 Homo sapiens
304150 Rattus norvegicus
30940 Mus musculus
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