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USP7 Proteins

(Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7))

Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilizes p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on p53/TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Involved in transcription-coupled recruited to DNA damage sites following interaction with KIAA1530/UVSSA and promotes deubiquitination of ERCC6, preventing UV-induced degradation of ERCC6 (By similarity).

recommended

USP7 Protein (AA 214-521) (His tag) (ABIN7125598)

USP7 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

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recommended

USP7 Protein (AA 13-110) (GST tag) (ABIN1324846)

USP7 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

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recommended

USP7 Protein (AA 1-1102) (Strep Tag) (ABIN3096200)

Crystallography grade USP7 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA

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USP7 Proteins by Grade

Find USP7 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

USP7 Proteins by Origin

Find USP7 Proteins for a variety of species such as anti-Human USP7. The species listed below are among those available. Click on a link to go to the corresponding products.

USP7 Proteins by Source

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USP7 Proteins by Protein Type

Here you can find USP7 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

USP7 Proteins by Application

Find USP7 Proteins validated for a specific application such as WB, ELISA, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular USP7 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

USP7 Protein (AA 214-521) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7125598

Quantity 50 μg

Datasheet Datasheet

USP7 Protein (AA 13-110) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1324846

Quantity 10 μg

Datasheet Datasheet

USP7 Protein (AA 1-1102) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3096200

Quantity 1 mg

Datasheet Datasheet

USP7 Protein (AA 54-507) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7416877

Quantity 100 μg

Datasheet Datasheet

USP7 Protein (AA 208-560) (GST tag,His tag)

Reactivity Human

Source Baculovirus infected Insect Cells

Validations

Cat. No. ABIN7198567

Quantity 100 μg

Datasheet Datasheet

USP7 Protein

Reactivity Human

Source Baculovirus infected Insect Cells

Validations

Cat. No. ABIN7198568

Quantity 100 μg

Datasheet Datasheet

USP7 Protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2735144

Quantity 20 μg

Datasheet Datasheet

Aliases for USP7 Proteins

Ubiquitin-specific protease 7 (Usp7) Proteins
ubiquitin carboxyl-terminal hydrolase 7 (LOC100201254) Proteins
ubiquitin specific peptidase 7 (USP7) Proteins
ubiquitin specific peptidase 7 (Usp7) Proteins
2210010O09Rik Proteins
AA409944 Proteins
AA617399 Proteins
AU019296 Proteins
AW548146 Proteins
C80752 Proteins
CG1490 Proteins
Dmel\\CG1490 Proteins
Hausp Proteins
HAUSP Proteins
TEF1 Proteins
UBP Proteins
USP7 Proteins

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USP7 Proteins by Grade

USP7 Proteins by Origin

USP7 Proteins by Source

USP7 Proteins by Protein Type

USP7 Proteins by Application

Popular USP7 Proteins

Aliases for USP7 Proteins

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