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USP8 Proteins

(Ubiquitin Specific Peptidase 8 (USP8))
Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell proliferation. Required to enter into S phase in response to serum stimulation. May regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and OTUB1. Probably regulates the stability of STAM2 and RASGRF1. Regulates endosomal ubiquitin dynamics, cargo sorting, membrane traffic at early endosomes, and maintenance of ESCRT-0 stability. The level of protein ubiquitination on endosomes is essential for maintaining the morphology of the organelle. Deubiquitinates EPS15 and controles tyrosine kinase stability. Removes conjugated ubiquitin from EGFR thus regulating EGFR degradation and downstream MAPK signaling. Involved in acrosome biogenesis through interaction with the spermatid ESCRT-0 complex and microtubules. Deubiquitinates BIRC6/bruce and KIF23/MKLP1.
USP8 Protein (AA 886-1096) (His tag) USP8 Protein (AA 886-1096) (His tag) USP8 Protein (AA 886-1096) (His tag) (ABIN7125599)

USP8 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

USP8 Protein (AA 777-1118) (His tag) (ABIN7398275)

USP8 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS, Imm, PC

USP8 Protein (AA 1-1118) (Strep Tag) (ABIN3096238)

USP8 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant > 80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA

USP8 Proteins by Origin

Find USP8 Proteins for a variety of species such as anti-Human USP8. The species listed below are among those available. Click on a link to go to the corresponding products.

USP8 Proteins by Source

Here you will find USP8 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

USP8 Proteins by Protein Type

Here you can find USP8 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

USP8 Proteins by Application

Find USP8 Proteins validated for a specific application such as AbP, STD, WB, ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular USP8 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125599
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7398275
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3096238
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2735146
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2735145
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2734893
Quantity 20 μg
Datasheet Datasheet

Aliases for USP8 Proteins

ubiquitin carboxyl-terminal hydrolase 8 (LOC9310109) Proteins
ubiquitin carboxyl-terminal hydrolase 8 (MGYG_00369) Proteins
ubiquitin specific peptidase 8 (USP8) Proteins
ubiquitin specific peptidase 8 (Usp8) Proteins
AI574262 Proteins
AW557536 Proteins
HumORF8 Proteins
mKIAA0055 Proteins
UBPY Proteins
Ubpy Proteins
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