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Browse our Angiotensin I Converting Enzyme 1 Proteins (ACE)

Full name:
Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 Proteins (ACE)
On www.antibodies-online.com are 23 Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE) Proteins from 8 different suppliers available. Additionally we are shipping Angiotensin I Converting Enzyme 1 Antibodies (210) and Angiotensin I Converting Enzyme 1 Kits (111) and many more products for this protein. A total of 350 Angiotensin I Converting Enzyme 1 products are currently listed.
Synonyms:
ACE, ACE1, AW208573, CD143, DCP, Dcp1, ICH, MVCD3, StsRR92, xace
list all proteins Gene Name GeneID UniProt
ACE 1636 P12821
Rat ACE ACE 24310 P47820
ACE 11421 P09470

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Angiotensin I Converting Enzyme 1 Proteins (ACE) by Origin

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Human Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE) interaction partners

  1. low circulating levels of ACE associated with significantly increased risk for small for gestational age newborn

  2. ACE and PDIA6 (show PDIA6 Proteins) were identified as potential HSPA2 (show HSPA2 Proteins)-interacting proteins; this assemblage resides in membrane raft microdomains located in the peri (show PLIN1 Proteins)-acrosomal region of the sperm head.

  3. In patients with ankylosing spondylitis, there were significantly higher levels of the ACE II genotype than in controls. Found higher levels of CRP (show CRP Proteins) and pain in the patients with ACE ID or DD genotypes compared to patients with ACE II genotypes

  4. Statistically significant association of the D allele of the ACE gene was observed between the case and control hypertensive subjects.

  5. ACE inhibitor therapy may increase erythropoietin (show EPO Proteins) resistance and worsen erythropoiesis in haemodialysis patients with the ACE D allele.

  6. The ACE gene insertion/deletion polymorphism is associated with the risk of pregnancy-induced hypertension.

  7. The simulation results in our work provide insights into the interactions between the two domains of ACE and its natural peptide inhibitor AngII at a molecular level. Moreover, the results provide theoretical clues for the design of new inhibitors

  8. The ACE I allele is found to be associated with type 2 diabetes mellitus; however, no association was observed with cardiovascular disease.

  9. ACE gene I allele might be a protective factor against gastric cancer, necessitating further confirmation in large, population-based studies.

  10. The findings of this study indicate that I/D polymorphisms of the ACE gene are a useful marker and are likely to play a major role in determining genetic susceptibility to end-stage renal disease in the Malaysian population.

Cow (Bovine) Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE) interaction partners

  1. The results indicate that the two active sites within bovine somatic ACE exhibit strong negative cooperativity.

  2. Phorbol 12-myristate 13-acetate (PMA) induced Egr-1 and ATF-2 binding to the ACE promoter, whereas Ets-1 binding was suppressed by PMA.

Mouse (Murine) Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE) interaction partners

  1. Intestinal ACE shedding is increased by DSS (show PMP22 Proteins)-induced intestinal inflammation and parallels local corticosterone production. ACE product angiotensin II stimulates corticosterone formation in healthy intestine.

  2. Renin (show REN Proteins) angiostensin system contributes to 20-HETE-mediated microvascular remodeling in hypertension and that 20-HETE-driven microvascular remodeling independent of blood pressure elevation does not fully rely on ACE activity in the vascular endothelium.

  3. angiotensin-converting enzyme has an essential role in hypertension induced by nitric oxide synthesis inhibition

  4. Suggest that the ACE2 (show ACE2 Proteins)-ACE imbalance plays an important role in the pathogenesis of severe acute pancreatitis and that pancreatic ACE2 (show ACE2 Proteins) is an important factor in determining the severity of SAP (show APCS Proteins).

  5. Show that tissue-specific targets are critical for the effects of miR (show MLXIP Proteins)-143/145 on smooth muscle differentiation and that angiotensin converting enzyme is one such target.

  6. Tissue-specific expression of transgenic secreted ACE in vasculature can restore normal kidney functions, but not blood pressure, of Ace-/- mice.

  7. ACE-null mice produce large numbers of myeloid-derived suppressor cells during chronic inflammation.

  8. Myelomonocytic expression of catalytically active ACE, prevents cognitive decline in a murine model of Alzheimer disease.

  9. ACE mediates angiotensin I-induced atherosclerosis, and ACE expression in leukocytes modestly contributes to atherosclerotic development in hypercholesterolemic mice.

  10. TEX101 is a unique specific substrate for ACE that is essential for the production of fertile mouse spermatozoa

Pig (Porcine) Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE) interaction partners

  1. Tissue Ang I (show AGT Proteins)-II conversion depends exclusively on the ACE C-domain, whereas both domains contribute to conversion by soluble ACE and to bradykinin degradation at tissue sites.

  2. The contributions of the C-domain and N-domain differ between DDs and IIs genotype

Rabbit Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE) interaction partners

  1. Corneal cells express ACE, AT(1) and AT(2)receptors. ACE inhibitor enalapril decreased corneal angiogenesis in VEGF (show VEGFA Proteins)-induced corneal neovascularization. ACE inhibitors may be novel therapy to treat corneal angiogenesis.

  2. Angiotensin-converting enzyme (ACE) residues encompassing 343 to 655 of the germinal form are required for its cleavage-secretion.

Angiotensin I Converting Enzyme 1 (ACE) Protein Profile

Protein Summary

This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active.

Alternative names and synonyms associated with Angiotensin I Converting Enzyme 1 (ACE)

  • angiotensin-converting enzyme (CpipJ_CPIJ009106)
  • angiotensin I converting enzyme (ace)
  • angiotensin I converting enzyme (ACE)
  • angiotensin I converting enzyme (Ace)
  • angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 (Ace)
  • angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 (ACE)
  • angiotensin I converting enzyme (peptidyl-dipeptidase A) 3 (ACE3)
  • angiotensin-converting enzyme-like (LOC100856208)
  • angiotensin-converting enzyme-like (LOC101824864)
  • ACE protein
  • ACE1 protein
  • AW208573 protein
  • CD143 protein
  • DCP protein
  • Dcp1 protein
  • ICH protein
  • MVCD3 protein
  • StsRR92 protein
  • xace protein

Protein level used designations for ACE

angiotensin-converting enzyme , angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 , angiotensin I converting enzyme 1 , CD143 antigen , angiotensin I converting enzyme peptidyl-dipeptidase A 1 transcript , angiotensin converting enzyme, somatic isoform , carboxycathepsin , dipeptidyl carboxypeptidase 1 , dipeptidyl carboxypeptidase I , kininase II , peptidase P , testicular ECA , Dipeptidyl carboxypeptidase 1 (Angiotensin I-converting enzyme) , angiotensin 1 converting enzyme 1 , angiotensin I-converting enzyme (Dipeptidyl carboxypeptidase 1) , angiotensin I-converting enzyme , dipeptidyl peptidase , angiotensin-I converting enzyme , peptidyl dipeptidase i , angiotensin converting enzyme , Angiotensin-converting enzyme, testis-specific isoform , dipeptidyl carboxy peptidase 1 , Dipeptidyl carboxypeptidase I , Kininase II

GENE ID SPECIES
6042069 Culex quinquefasciatus
100144634 Xenopus (Silurana) tropicalis
1636 Homo sapiens
24310 Rattus norvegicus
509484 Bos taurus
11421 Mus musculus
613133 Sus scrofa
100009274 Oryctolagus cuniculus
610668 Canis lupus familiaris
419953 Gallus gallus
554335 Ovis aries
449567 Pan troglodytes
100295485 Bos taurus
100856208 Canis lupus familiaris
101824864 Mesocricetus auratus
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