Browse our anti-CD109 (CD109) Antibodies

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anti-CD109 Antigen Antibodies (CD109)
On are 0 CD109 Antigen (CD109) Antibodies from different suppliers available. A total of 0 CD109 products are currently listed.
9930012E15Rik, AI480638, D11S833E, GARP
list all antibodies Gene Name GeneID UniProt
Anti-Mouse CD109 CD109 235505 Q8R422
Anti-Human CD109 CD109 2615 Q14392

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More Antibodies against CD109 Interaction Partners

Mouse (Murine) CD109 Antigen (CD109) interaction partners

  1. platelet and endothelial GARP (show LRRC32 Antibodies) are not important in hemostasis and thrombosis in mice

  2. Small-scale in vivo screening identified several genes, including Cd109, that encode novel pro-metastatic factors. We uncovered signaling mediated by Janus kinases (Jaks) and the transcription factor Stat3 (show STAT3 Antibodies) as a critical, pharmacologically targetable effector of CD109-driven lung cancer metastasis

  3. CD109 differentially regulates TGF-beta (show TGFB1 Antibodies)-induced ALK1 (show ACVRL1 Antibodies)-Smad1 (show SMAD1 Antibodies)/5 versus ALK5 (show TGFBR1 Antibodies)-Smad2 (show SMAD2 Antibodies)/3 pathways, leading to decreased extracellular matrix production in the skin; epidermal CD109 expression regulates dermal function through a paracrine mechanism

  4. the GARP (show LRRC32 Antibodies)/LTGF-beta1 complex on Treg cells is a major source of TGF-beta1 (show TGFB1 Antibodies) needed for induction of pTreg cells during the process of oral tolerance.

  5. GP96 (show HSP90B1 Antibodies) serves as an essential chaperone for the cell-surface protein (show CD28 Antibodies) glycoprotein A repetitions predominant (GARP (show LRRC32 Antibodies)), which is a docking receptor for latent membrane-associated TGF-beta (show TGFB1 Antibodies) (mLTGF-beta).

  6. CD109 decreases extracellular matrix production and fibrotic responses during hypoxic wound healing

  7. CD109 is present in serum as a soluble form, and suggest its potential as a novel tumor marker in patients with cancers that express CD109.

  8. CD109 might be an important regulator of osteoclastogenesis.

  9. findings demonstrate that CD109 overexpression in the epidermis reduces inflammation and granulation tissue area and improves collagen organization in vivo.

  10. Induction of both Th17-producing cells and Tregs is caused preferentially by Tregs expressing the latent TGF-beta1 (show TGFB1 Antibodies)/GARP (show LRRC32 Antibodies) complex on their cell surface rather than by secreted latent TGF-beta1 (show TGFB1 Antibodies).

Human CD109 Antigen (CD109) interaction partners

  1. GARP (show CNGB1 Antibodies) plays an important role in the pathogenesis of atopic dermatitis.

  2. CD4 (show CD4 Antibodies)(+) CD25 (show IL2RA Antibodies)(+) GARP (show CNGB1 Antibodies)(+) Treg cells are defective in dilated cardiomyopathy patients and GARP (show CNGB1 Antibodies) seems to be a better molecular definition of the regulatory phenotype.

  3. these results define the oncogenic effects of the GARP (show CNGB1 Antibodies)-TGFbeta (show TGFB1 Antibodies) axis in the tumor microenvironment

  4. LRRC32 (show LRRC32 Antibodies) expression is significantly upregulated in human masticatory mucosa during wound healing

  5. GARP (show CNGB1 Antibodies) deficiency leads to accumulation of sphingolipid synthesis intermediates, changes in sterol distribution, and lysosomal dysfunction.

  6. since GARP (show CNGB1 Antibodies) functions as a transporter of transforming growth factor beta (TGFbeta (show TGFB1 Antibodies)), a cytokine with broad pleiotropic traits, GARP (show CNGB1 Antibodies) transcriptional attenuation by alternative promoters might provide a mechanism regulating peripheral TGFb (show TGFB1 Antibodies)

  7. GARP (show CNGB1 Antibodies) is regulated by miRNAs and controls latent TGF-beta1 (show TGFB1 Antibodies) production by human regulatory T cells.

  8. we investigated in detail miR (show MLXIP Antibodies)-142-3 pregulation of GARP (show CNGB1 Antibodies) expression in regulatory CD25 (show IL2RA Antibodies)(+) CD4 (show CD4 Antibodies) T cells

  9. Findings support the idea that GARP (show CNGB1 Antibodies) is a new latent TGFbeta-binding protein (show LTBP1 Antibodies) that regulates the bioavailability of TGFbeta (show TGFB1 Antibodies) and provides a cell surface platform for alphaV integrin (show ITGAV Antibodies)-dependent TGFbeta (show TGFB1 Antibodies) activation.

  10. There are 2 independent signals, one in C11orf30 and the other in LRRC32, that are strongly associated with serum IgE levels. C11orf30-LRRC32 region may represent a common locus for atopic diseases via pathways involved in regulation of serum IgE levels

CD109 Antigen Profile

Antigen Summary

This gene encodes a type I membrane protein which contains 20 leucine-rich repeats. Alterations in the chromosomal region 11q13-11q14 are involved in several pathologies.

Alternative names and synonyms associated with CD109

  • CD109 antigen (Cd109) antibody
  • leucine rich repeat containing 32 (LRRC32) antibody
  • 9930012E15Rik antibody
  • AI480638 antibody
  • D11S833E antibody
  • GARP antibody

Protein level used designations for anti-CD109 Antigen (CD109) Antibodies

GPI-anchored alpha 2 macroglobulin-related protein , GPI-anchored alpha-2 macroglobulin-related protein , Gov platelet alloantigens , garpin , glycoprotein A repetitions predominant , leucine-rich repeat-containing protein 32

235505 Mus musculus
2615 Homo sapiens
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