CD109 antibody

Catalog No. ABIN6559811

The Mouse Monoclonal anti-CD109 antibody (Clone W7C5) (ABIN6559811) specifically detects CD109 in FACS. The antibody is reactive with Human samples.

Quick Overview for CD109 antibody (ABIN6559811)

Target: CD109

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD109 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: W7C5

Product Details anti-CD109 Antibody

Purpose: Anti-Hu CD109 Purified

Cross-Reactivity (Details): Human

Characteristics: The mouse monoclonal antibody W7C5 recognizes CD109, an approximately 165 kDa GPI-anchored extracellular protein expressed mainly on various hematopoietic cells, activated T lymphoblasts, activated platelets, and endothelial cells.

Purification: Purified by protein-A affinity chromatography.

Purity: > 95 % (by SDS-PAGE)

Immunogen: WERI-RB-1 retinoblastoma cell line

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: Recommended dilution: 1-4 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for CD109

Target: CD109

Alternative Name: CD109

Background: CD109 Molecule,CD109, also known as the Gov platelet alloantigen, is a GPI-anchored glycoprotein which localizes to the surface of platelets, activated T-cells, and endothelial cells, as well as of various hematopoietic cells and T cell lines. The protein binds to and negatively regulates signaling by transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene. The Gov antigen system is involved in platelet transfusion reaction, posttransfusion purpura and in neonatal alloimmune thrombocytopenia.,CPAMD7, p180, r150, FLJ38569, GPA

Gene ID: 135228

UniProt: Q6YHK3

Pathways: Activated T Cell Proliferation