Browse our anti-CLEC7A (CLEC7A) Antibodies

Full name:
anti-C-Type Lectin Domain Family 7, Member A Antibodies (CLEC7A)
On are 207 C-Type Lectin Domain Family 7, Member A (CLEC7A) Antibodies from 22 different suppliers available. Additionally we are shipping CLEC7A Kits (21) and CLEC7A Proteins (14) and many more products for this protein. A total of 253 CLEC7A products are currently listed.
beta-GR, BGR, CANDF4, CLEC7A, Clec7b, CLECSF12, DECTIN1, RGD1565140
list all antibodies Gene Name GeneID UniProt
CLEC7A 56644 Q6QLQ4
CLEC7A 64581 Q9BXN2
CLEC7A 502902  

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Most Popular Reactivities for anti-CLEC7A (CLEC7A) Antibodies

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anti-Mouse (Murine) CLEC7A Antibodies:

anti-Human CLEC7A Antibodies:

anti-Rat (Rattus) CLEC7A Antibodies:

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Top referenced anti-CLEC7A Antibodies

  1. Mouse (Murine) Monoclonal CLEC7A Primary Antibody for Func, FACS - ABIN181895 : Reid, Montoya, Taylor, Borrow, Gordon, Brown, Wong: Expression of the beta-glucan receptor, Dectin-1, on murine leukocytes in situ correlates with its function in pathogen recognition and reveals potential roles in leukocyte interactions. in Journal of leukocyte biology 2004 (PubMed)
    Show all 7 references for 181895

  2. Human Monoclonal CLEC7A Primary Antibody for FACS - ABIN4897736 : Cunha, Di Ianni, Bozza, Giovannini, Zagarella, Zelante, DAngelo, Pierini, Pitzurra, Falzetti, Carotti, Perruccio, Latgé, Rodrigues, Velardi, Aversa, Romani, Carvalho et al.: Dectin-1 Y238X polymorphism associates with susceptibility to invasive aspergillosis in hematopoietic transplantation through impairment of both recipient- and donor-dependent mechanisms of ... in Blood 2010 (PubMed)
    Show all 6 references for 4897736

  3. Mouse (Murine) Monoclonal CLEC7A Primary Antibody for FACS - ABIN320108 : Brown, Taylor, Reid, Willment, Williams, Martinez-Pomares, Wong, Gordon: Dectin-1 is a major beta-glucan receptor on macrophages. in The Journal of experimental medicine 2002 (PubMed)
    Show all 4 references for 320108

  4. Mouse (Murine) Monoclonal CLEC7A Primary Antibody for FACS, IHC (fro) - ABIN181896 : Taylor, Brown, Reid, Willment, Martinez-Pomares, Gordon, Wong: The beta-glucan receptor, dectin-1, is predominantly expressed on the surface of cells of the monocyte/macrophage and neutrophil lineages. in Journal of immunology (Baltimore, Md. : 1950) 2002 (PubMed)
    Show all 4 references for 181896

  5. Human Polyclonal CLEC7A Primary Antibody for EIA, IF - ABIN1449932 : Kerrigan, Brown: Syk-coupled C-type lectin receptors that mediate cellular activation via single tyrosine based activation motifs. in Immunological reviews 2010 (PubMed)
    Show all 4 references for 1449932

  6. Mouse (Murine) Monoclonal CLEC7A Primary Antibody for FACS - ABIN181894 : Underhill, Rossnagle, Lowell, Simmons: Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production. in Blood 2005 (PubMed)
    Show all 2 references for 181894

  7. Human Polyclonal CLEC7A Primary Antibody for WB - ABIN4304728 : Cohen-Kedar, Baram, Elad, Brazowski, Guzner-Gur, Dotan: Human intestinal epithelial cells respond to β-glucans via Dectin-1 and Syk. in European journal of immunology 2014 (PubMed)

  8. Mouse (Murine) Monoclonal CLEC7A Primary Antibody for FACS - ABIN4897760 : Xu, Huo, Gunawan, Su, Lam: Activated dectin-1 localizes to lipid raft microdomains for signaling and activation of phagocytosis and cytokine production in dendritic cells. in The Journal of biological chemistry 2009 (PubMed)

  9. Human Monoclonal CLEC7A Primary Antibody for FACS - ABIN4897732 : Sindrilaru, Peters, Wieschalka, Baican, Baican, Peter, Hainzl, Schatz, Qi, Schlecht, Weiss, Wlaschek, Sunderkötter, Scharffetter-Kochanek: An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice. in The Journal of clinical investigation 2011 (PubMed)

More Antibodies against CLEC7A Interaction Partners

Pig (Porcine) C-Type Lectin Domain Family 7, Member A (CLEC7A) interaction partners

  1. These results suggest that functionally neutral polymorphisms in dectin-1 are widespread in pig populations

  2. recognition of beta-glucans appeared cell type-specific as both dectin-1 and CR3 (show ITGAM Antibodies) are involved in the beta-glucan-mediated responses in pig macrophages.

Mouse (Murine) C-Type Lectin Domain Family 7, Member A (CLEC7A) interaction partners

  1. these results suggest that Dectin-1 expressed on CD11b (show ITGAM Antibodies)(+) dendritic cells (DCs) senses some molecule(s) in house dust mite (HDM (show HDAC3 Antibodies)) extract and plays a critical role in the induction of HDM (show HDAC3 Antibodies)-induced allergic airway inflammation by inducing the expression of chemokine/chemokine (show CCL1 Antibodies) receptors in DCs.

  2. The sum of the data suggests that in contrast to IgG-based immune complexes boosting immune reactivity of antigen-presenting cells, secretory IgA produced during an ongoing immune response can, in addition to its known function of immune exclusion, modulate mucosal dendritic cell conditioning via specific interaction with Dectin-1 and SIGNR3.

  3. data suggest that the C-Type lectin receptor (show CLEC4D Antibodies) Dectin-1 is a major pattern recognition receptor that orchestrates miR155 upregulation in a Syk (show SYK Antibodies)-dependent manner; results suggest that PRR (show PVRL1 Antibodies)-mediating signaling events are key drivers of miRNA-mediated gene regulation during fungal pathogenesis

  4. results strongly suggest that Ae2 (show SLC4A2 Antibodies) is a critical factor in the innate response to C. albicans. This study represents an important contribution to a better understanding of how Dectin-1 expression and fungal clearance is regulated.

  5. this study shows that in vitro, cytokine production by bone marrow-derived dendritic cells is dependent on dectin-1; in vivo, its deficiency compromises fungal clearance

  6. SCIMP (show SCIMP Antibodies) is strongly phosphorylated after Dectin-1 stimulation and that it participates in signal transduction downstream of this important pattern recognition receptor.

  7. dectin-1 has a role in glycyrrhetinic acid inhibition of contact hypersensitivity induced by trichophytin

  8. CD4 (show CD4 Antibodies)(+) T-cell survival in the gastrointestinal tract tract requires dectin-1 during Canida infection.

  9. Our present study suggested that Dectin-1 is a novel receptor for Trichosporon asahii and demonstrates the critical role of Dectin-1 in the development of T. asahii-induced hypersensitivity pneumonitis.

  10. Mast cells are able to phagocytose and produce nitric oxide against Candida albicans via TLR2 (show TLR2 Antibodies)/Dectin-1.

Human C-Type Lectin Domain Family 7, Member A (CLEC7A) interaction partners

  1. Dectin-1-mediated activation of the Syk (show SYK Antibodies), MAPKs, PI3K (show PIK3CA Antibodies) and NF-kappaB (show NFKB1 Antibodies) signaling pathways contributes to F. proliferatum-stimulated CXCL-8 (show IL8 Antibodies) release from BEAS-2B cells and provides an important basis for developing novel therapeutic strategies in clinical allergy.

  2. this study shows that curdlan inhibits tumor growth via activating dendritic cells through dectin-1 signaling

  3. Dectin-1 is essential for efficient immune response against Mycobacteria.

  4. dectin-1 has a role in glycyrrhetinic acid inhibition of contact hypersensitivity induced by trichophytin

  5. study represents the first analysis demonstrating that harbouring polymorphisms of Dectin-1 (rs7309123) or TLR2 (show TLR2 Antibodies) (rs5743708) represents an independent risk factor of developing IFD in patients with AML (show RUNX1 Antibodies) undergoing induction chemotherapy.

  6. TREM-1 (show TREM1 Antibodies) and Dectin-1 function concurrently in the corneal innate immune response by regulating inflammatory cytokine expression in fungal keratitis.

  7. Our data suggest that the genetic diversity of CLEC7A gene influences the autism spectrum disorders (ASD (show ARSD Antibodies)) phenotype by behaving as a disease specifier and imply that the genetic control of innate immune response could determine the ASD (show ARSD Antibodies) phenotype.

  8. The result of this study suggests that there is no correlation between Dectin-1 Y238X Gene polymorphism and RVVC.

  9. This study demonstrated that Toll (show TLR4 Antibodies)-Like Receptors and Dectin-1, a C-Type Lectin Receptor (show CLEC4D Antibodies), Trigger Divergent Functions in CNS Macrophages.

  10. Data indicate that Candida albicans beta-Glucan induces high IL-1 (show IL1A Antibodies) receptor antagonist (IL-1Ra (show IL1RN Antibodies)) levels, independently from Dectin-1/complement receptor 3 (CR3 (show ITGAM Antibodies)).

Cow (Bovine) C-Type Lectin Domain Family 7, Member A (CLEC7A) interaction partners

  1. CLEC7a genetic variant c.589A>G was significantly associated (p = 0.008) with Mycobacterium avium ssp. paratuberculosis infection in Holsteins cattle.

CLEC7A Antigen Profile

Antigen Summary

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Alternative names and synonyms associated with CLEC7A

  • C-type lectin domain family 7, member A (CLEC7A) antibody
  • C-type lectin domain family 7, member a (Clec7a) antibody
  • C-type lectin domain family 7, member A (Clec7a) antibody
  • dendritic cell-associated C-type lectin 1 (LOC100339146) antibody
  • beta-GR antibody
  • BGR antibody
  • CANDF4 antibody
  • CLEC7A antibody
  • Clec7b antibody
  • CLECSF12 antibody
  • DECTIN1 antibody
  • RGD1565140 antibody

Protein level used designations for CLEC7A

dendritic cell-associated C-type lectin 1 , C-type lectin domain family 7, member A , C-type lectin domain family 7 member A , dectin 1 , C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12 , C-type lectin superfamily member 12 , DC-associated C-type lectin 1 , beta-glucan receptor , dectin-1 , C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12 , dendritic cell-associated C-type lectin-1 , lectin-like receptor 1

473361 Pan troglodytes
611385 Canis lupus familiaris
678685 Ovis aries
100038025 Sus scrofa
56644 Mus musculus
64581 Homo sapiens
532865 Bos taurus
502902 Rattus norvegicus
574356 Macaca mulatta
100339146 Oryctolagus cuniculus
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