CLEC7A antibody

Catalog No. ABIN7013961

Product Details anti-CLEC7A Antibody

Target: CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CLEC7A antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: The mouse monoclonal antibody 15E2 recognizes an extracellular epitope LWEDGSTFSSN of human CD369 (Dectin-1), a 33 kDa transmembrane glycoprotein expressed predominantly on dendritic cells.

Purification: Purified by protein-A affinity chromatography.

Immunogen: Extracellular part of human CD369 with hIgG FC tag

Clone: 15E2

Isotype: IgG2a kappa

Application Details

Application Notes: Flow cytometry: Recommended dilution: 2-5 μg/mL.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for CLEC7A

Target: CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))

Alternative Name: CD369 (CLEC7A Products)

Synonyms: CLEC7A antibody, BGR antibody, Clecsf12 antibody, beta-GR antibody, CANDF4 antibody, CLECSF12 antibody, DECTIN1 antibody, Clec7b antibody, RGD1565140 antibody, C-type lectin domain containing 7A antibody, C-type lectin domain family 7, member a antibody, CLEC7A antibody, Clec7a antibody

Background: C-type lectin domain containing 7A,CD369 (dectin-1, beta-glucan receptor) is a 33 kDa type II transmembrane glycoprotein of lectin family, and serves as a part of innate immunity system by binding to beta-glucan polymers, which are typical for yeast and mycobacterial cell walls. CD369 is expressed predominantly on dendritic cells, but it can be detected also on monocytes, macrophages, mast cells, eosinophils, B cells, endothelial cells, and sometimes also on some T cell subsets.,Dectin-1, CLEC7A, BGR, CANDF4, SCARE2

Gene ID: 64581

UniProt: Q9BXN2

Pathways: Activation of Innate immune Response