You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our anti-NLRC4 (NLRC4) Antibodies

Full name:
anti-NLR Family, CARD Domain Containing 4 Antibodies (NLRC4)
On www.antibodies-online.com are 98 NLR Family, CARD Domain Containing 4 (NLRC4) Antibodies from 22 different suppliers available. Additionally we are shipping NLRC4 Kits (10) and NLRC4 Proteins (3) and many more products for this protein. A total of 116 NLRC4 products are currently listed.
Synonyms:
9530011P19Rik, Card12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, IPAF
list all antibodies Gene Name GeneID UniProt
NLRC4 58484 Q9NPP4
NLRC4 268973  
NLRC4 298784  

Show all species

Show all synonyms

Most Popular Reactivities for anti-NLRC4 (NLRC4) Antibodies

Select your species and application

anti-Human NLRC4 Antibodies:

anti-Mouse (Murine) NLRC4 Antibodies:

anti-Rat (Rattus) NLRC4 Antibodies:

All available anti-NLRC4 Antibodies

Go to our pre-filtered search.

Top referenced anti-NLRC4 Antibodies

  1. Human Monoclonal NLRC4 Primary Antibody for FACS - ABIN2665296 : Cai, Batra, Wakamatsu, Pacher, Jeyaseelan: NLRC4 inflammasome-mediated production of IL-1β modulates mucosal immunity in the lung against gram-negative bacterial infection. in Journal of immunology (Baltimore, Md. : 1950) 2012 (PubMed)
    Show all 5 references for ABIN2665296

  2. Human Polyclonal NLRC4 Primary Antibody for EIA, IF - ABIN500034 : Poyet, Srinivasula, Tnani, Razmara, Fernandes-Alnemri, Alnemri: Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1. in The Journal of biological chemistry 2001 (PubMed)
    Show all 3 references for ABIN500034

  3. Human Polyclonal NLRC4 Primary Antibody for IHC (fro), IHC (p) - ABIN252142 : Akhter, Caution, Abu Khweek, Tazi, Abdulrahman, Abdelaziz, Voss, Doseff, Hassan, Azad, Schlesinger, Wewers, Gavrilin, Amer: Caspase-11 promotes the fusion of phagosomes harboring pathogenic bacteria with lysosomes by modulating actin polymerization. in Immunity 2012 (PubMed)

  4. Human Polyclonal NLRC4 Primary Antibody for IHC, WB - ABIN2792097 : Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ... in Genome research 2003 (PubMed)

  5. Human Polyclonal NLRC4 Primary Antibody for WB - ABIN657230 : Vinzing, Eitel, Lippmann, Hocke, Zahlten, Slevogt, Nguessan, Günther, Schmeck, Hippenstiel, Flieger, Suttorp, Opitz: NAIP and Ipaf control Legionella pneumophila replication in human cells. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)

  6. Human Polyclonal NLRC4 Primary Antibody for WB - ABIN153028 : Cividini, Tozzi, Galli, Pesi, Camici, Dumontet, Jordheim, Allegrini: Cytosolic 5'-nucleotidase II interacts with the leucin rich repeat of NLR family member Ipaf. in PLoS ONE 2015 (PubMed)

More Antibodies against NLRC4 Interaction Partners

Human NLR Family, CARD Domain Containing 4 (NLRC4) interaction partners

  1. High expression of NLRP3 (show NLRP3 Antibodies), NLRC4, and CASP1 (show CASP1 Antibodies) in background non-tumorous liver is significantly correlated with poor prognosis of patients after resection of hepatocellular carcinoma.

  2. association of IL-18 (show IL18 Antibodies) levels with a single nucleotide polymorphism in the untranslated exon 2 of the inflammasome component NLRC4

  3. While both contributing to pathogen clearance, NLRP3 (show NLRP3 Antibodies) more than NLRC4 contributes to deleterious inflammatory responses in cystic fibrosis (show S100A8 Antibodies) and correlates with defective NLRC4-dependent IL-1Ra (show IL1RN Antibodies) production.

  4. analysis of a subset of inflammasome receptors including NLRP3 (show NLRP3 Antibodies), NLRC4 and AIM2 (show AIM2 Antibodies) that triggers formation of the micrometer-sized spherical supramolecular complex called the ASC (show PYCARD Antibodies) speck

  5. Thus, pathogenic inflammasome activity during Candida infection is negatively regulated by the IL-22 (show IL22 Antibodies)/NLRC4/IL-1Ra (show IL1RN Antibodies) axis.

  6. cN-II (show NT5C2 Antibodies) co-immunoprecipitated both with wild type Ipaf and its LRR domain after transfection with corresponding expression vectors, but not with Ipaf lacking the LRR domain.

  7. Elevated expression of IPAF was associated with inflammation in patients with pemphigus vulgaris (show DSG3 Antibodies) disease.

  8. Data indicate that NLR family CARD domain containing 4 protein (NLRC4) is a causative gene for familial cold autoinflammatory syndrome (FCAS).

  9. Data show that the disease was caused by a de novo gain-of-function mutation in NLR family CARD domain containing 4 (NLRC4) encoding a p.Val341Ala substitution.

  10. inflammasome (also known as NLRC4) has been demonstrated to play a role in host defense mechanisms against pathogen-associated molecules

Mouse (Murine) NLR Family, CARD Domain Containing 4 (NLRC4) interaction partners

  1. These data reveal mild constitutive activation of the Nlrc4 inflammasome as the results of two SNPs, which leads to the stimulation of hepatocyte proliferation. The increased liver regeneration induces rapid liver mass recovery after hepatectomy and may prevent the development of hepatotoxin-induced liver fibrosis.

  2. While both contributing to pathogen clearance, NLRP3 (show NLRP3 Antibodies) more than NLRC4 contributes to deleterious inflammatory responses in cystic fibrosis (show S100A8 Antibodies) and correlates with defective NLRC4-dependent IL-1Ra (show IL1RN Antibodies) production.

  3. The wheel-like structure of a PrgJ-NAIP2-NLRC4 complex determined by cryogenic electronmicroscopy at 6.6 angstrom reveals that NLRC4 activation involves substantial structural reorganization that creates one oligomerization surface (catalytic surface).

  4. caspase-1 (show CASP1 Antibodies) is activated in macrophages under hypertonic conditions through NLRP3 (show NLRP3 Antibodies) and NLRC4 inflammasome activation.

  5. These results show that NLRC4 and TLR5 (show TLR5 Antibodies), key components of two flagellin (show FliC Antibodies) sensing pathways, each contribute to host defense in respiratory melioidosis.

  6. Data show that caspase-1 (show CASP1 Antibodies) but not caspase-11 (show CASP4 Antibodies) was essential for the functional activities of the NLRC4 inflammasome.

  7. TLR4 (show TLR4 Antibodies) activation induces IL-1beta (show IL1B Antibodies) release via an IPAF dependent but caspase 1 (show CASP1 Antibodies)/11/8 independent pathway in the lung.

  8. The present findings demonstrated that mice deficient in NLRC4 or ASC (show STS Antibodies), but not in NLRP3 (show NLRP3 Antibodies), present reduced mechanical and thermal acute inflammatory hyperalgesia induced by carrageenan

  9. AIM2 (show AIM2 Antibodies) and NLRC4 inflammasomes contribute with ASC (show STS Antibodies) to acute brain injury independently of NLRP3 (show NLRP3 Antibodies)

  10. Data indicate that transgenic mice that expressed mutant NLR family CARD domain containing 4 protein (NLRC4) developed dermatitis and arthritis.

NLRC4 Antigen Profile

Antigen Summary

In C. elegans, Ced4 binds and activates Ced3, an apoptotic initiator caspase, via caspase-associated recruitment domains (CARDs). Human Ced4 homologs include APAF1 (MIM 602233), NOD1/CARD4 (MIM 605980), and NOD2/CARD15 (MIM 605956). These proteins have at least 1 N-terminal CARD domain followed by a centrally located nucleotide-binding domain (NBD or NACHT) and a C-terminal regulatory domain, found only in mammals, that contains either WD40 repeats or leucine-rich repeats (LRRs). CARD12 is a member of the Ced4 family and can induce apoptosis.

Alternative names and synonyms associated with NLRC4

  • NLR family, CARD domain containing 4 (NLRC4) antibody
  • NLR family, CARD domain containing 4 (Nlrc4) antibody
  • 9530011P19Rik antibody
  • Card12 antibody
  • CLAN antibody
  • CLAN1 antibody
  • CLANA antibody
  • CLANB antibody
  • CLANC antibody
  • CLAND antibody
  • CLR2.1 antibody
  • IPAF antibody

Protein level used designations for NLRC4

caspase recruitment domain protein 12 , NLR family CARD domain-containing protein 4 , ice protease-activating factor , ipaf , NLR family, CARD domain containing 4 , CARD, LRR, and NACHT-containing protein , ICE-protease activating factor , NOD-like receptor C4 , caspase recruitment domain family, member 12 , caspase recruitment domain-containing protein 12 , nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 4

GENE ID SPECIES
459135 Pan troglodytes
512480 Bos taurus
706378 Macaca mulatta
100070605 Equus caballus
58484 Homo sapiens
268973 Mus musculus
298784 Rattus norvegicus
Selected quality suppliers for anti-NLRC4 (NLRC4) Antibodies
Did you look for something else?