NLRC4 antibody (AA 941-990)

Catalog No. ABIN6735855

This Rabbit Polyclonal antibody specifically detects NLRC4 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat and Guinea Pig.

Quick Overview for NLRC4 antibody (AA 941-990) (ABIN6735855)

Target: NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))

Reactivity: Human, Mouse, Rat, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRC4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-NLRC4 Antibody

Binding Specificity: AA 941-990

Specificity: Human NLRC4 / IPAF

Predicted Reactivity: Percent identity by BLAST analysis: Human (100%) Mouse (86%) Rat, Guinea pig (80%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa941-990 of human NLRC4 (Q9NPP4, NP_067032). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla (100%), Gibbon, Monkey (93%), Galago, Mouse (86%), Rat, Elephant, Bat, Guinea pig (80%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: IHC, WB (0.2 - 1 μg/mL)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: After adding water, will consist of PBS buffer with 2 % sucrose

Concentration: Lot specific

Buffer: Lyophilized.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for NLRC4

Target: NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))

Alternative Name: IPAF / NLRC4

Background: Name/Gene ID: NLRC4
Family: Apoptosis

Synonyms: NLRC4, CARD12, CLANA, CLANB, CLANC, CLAND, CLAN, CLR2.1, Clan protein, CLAN1, Ice protease-activating factor, NOD-like receptor C4, ICE-protease activating factor, IPAF

Gene ID: 58484

NCBI Accession: NP_067032

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome