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NLRP3 Antibodies

(NLR Family, Pyrin Domain Containing 3 (NLRP3))
This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are suggested by available data\; however, insufficient evidence is available to determine if all of the represented 5' UTR splice patterns are biologically valid. [provided by RefSeq, Oct 2008].
NLRP3 antibody  (Pyrin Domain) NLRP3 antibody  (Pyrin Domain) NLRP3 antibody (Pyrin Domain) (ABIN1169100)

NLRP3 Reactivity: Human, Mouse IF, IHC, IP, WB Host: Mouse Monoclonal Cryo-2 unconjugated

NLRP3 antibody  (AA 15-120) NLRP3 antibody  (AA 15-120) NLRP3 antibody (AA 15-120) (ABIN1386361)

NLRP3 Reactivity: Human, Mouse, Rat, Dog ELISA, FACS, ICC, IF (cc), IF (p), IHC (fro), IHC (p), WB Host: Rabbit Polyclonal unconjugated

NLRP3 antibody  (AA 671-1033) NLRP3 antibody  (AA 671-1033) NLRP3 antibody (AA 671-1033) (ABIN7443710)

NLRP3 Reactivity: Mouse ICC, IHC, IP, WB Host: Rabbit Polyclonal unconjugated

NLRP3 Antibodies by Grade

Find NLRP3 Antibodies with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

NLRP3 Antibodies by Reactivity

Find NLRP3 Antibodies for a variety of species such as anti-Human NLRP3, anti-Mouse NLRP3, anti-Rat NLRP3. The species listed below are among those available. Click on a link to go to the corresponding products.

NLRP3 Antibodies by Application

Find NLRP3 Antibodies validated for a specific application such as WB, ELISA, FACS, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

NLRP3 Antibodies by Host

Find NLRP3 Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

NLRP3 Antibodies by Binding Specificity

Find NLRP3 Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

NLRP3 Antibodies by Clonality

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NLRP3 Antibodies by Clone

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NLRP3 Antibodies by Conjugate

Find NLRP3 Antibodies with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular NLRP3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application IF, IHC, IP, WB
Validations
  • (60)
  • (5)
Cat. No. ABIN1169100
Quantity 100 μg
Datasheet Datasheet
Reactivity Dog, Human, Mouse, Rat
Application ELISA, FACS, ICC, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
  • (11)
  • (15)
Cat. No. ABIN1386361
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application ICC, IHC, IP, WB
Validations
  • (8)
Cat. No. ABIN7443710
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, FACS, IF
Validations
  • (8)
Cat. No. ABIN184887
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IF, IHC
Validations
  • (6)
Cat. No. ABIN7256306
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application FACS, ICC, IF, IHC (p), WB
Validations
  • (7)
Cat. No. ABIN3032021
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IF, IHC, WB
Validations
  • (5)
Cat. No. ABIN6144662
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC (p), WB
Validations
  • (3)
  • (2)
Cat. No. ABIN652504
Quantity 400 μL
Datasheet Datasheet
Reactivity Dog, Human, Monkey
Application IHC, IHC (p), WB
Validations
  • (3)
Cat. No. ABIN6749780
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
  • (2)
Cat. No. ABIN3043571
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA, WB
Validations
  • (3)
Cat. No. ABIN3032020
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
Cat. No. ABIN3032019
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, IHC
Validations
  • (2)
Cat. No. ABIN7160827
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (2)
Cat. No. ABIN530254
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA, WB
Validations
  • (2)
Cat. No. ABIN2447023
Quantity 400 μL
Datasheet Datasheet

Latest Publications for our NLRP3 Antibodies

Qu, Fan, Qi, Xu, Hu, Chen, Liu, Liu, Si: "Akkermansia muciniphila Alleviates Dextran Sulfate Sodium (DSS)-Induced Acute Colitis by NLRP3 Activation." in: Microbiology spectrum, Vol. 9, Issue 2, pp. e0073021, (2022) (PubMed).

Lv, Liu, Ye, Yang, Duan, Yao, Li, Tang, Chen, Liu, Deng, Wang, Xing, Liang, Xu, Ye: "XIST Inhibition Attenuates Calcium Oxalate Nephrocalcinosis-Induced Renal Inflammation and Oxidative Injury via the miR-223/NLRP3 Pathway." in: Oxidative medicine and cellular longevity, Vol. 2021, pp. 1676152, (2022) (PubMed).

An, Zhang, Cao, Chen, Qin, Yang: "Punicalagin Protects Diabetic Nephropathy by Inhibiting Pyroptosis Based on TXNIP/NLRP3 Pathway." in: Nutrients, Vol. 12, Issue 5, (2021) (PubMed).

Li, Jiang, Ye, Zhou, Liu, Yang, Hao, Hu: "P2Y14 receptor has a critical role in acute gouty arthritis by regulating pyroptosis of macrophages." in: Cell death & disease, Vol. 11, Issue 5, pp. 394, (2021) (PubMed).

Zhou, Xiao, Zhao, Tan, Long, Yu, He: "Enhanced Autolysosomal Function Ameliorates the Inflammatory Response Mediated by the NLRP3 Inflammasome in Alzheimer's Disease." in: Frontiers in aging neuroscience, Vol. 13, pp. 629891, (2021) (PubMed).

Wu, Pan, Luo, Shen, Meng, Xiao, Tan, Nie, Tong, Wang: "Roseburia intestinalis‑derived flagellin ameliorates colitis by targeting miR‑223‑3p‑mediated activation of NLRP3 inflammasome and pyroptosis." in: Molecular medicine reports, Vol. 22, Issue 4, pp. 2695-2704, (2021) (PubMed).

Ershaid, Sharon, Doron, Raz, Shani, Cohen, Monteran, Leider-Trejo, Ben-Shmuel, Yassin, Gerlic, Ben-Baruch, Pasmanik-Chor, Apte, Erez: "NLRP3 inflammasome in fibroblasts links tissue damage with inflammation in breast cancer progression and metastasis." in: Nature communications, Vol. 10, Issue 1, pp. 4375, (2020) (PubMed).

Zhu, Tang: "LncRNA Gm14205 induces astrocytic NLRP3 inflammasome activation via inhibiting oxytocin receptor in postpartum depression." in: Bioscience reports, Vol. 40, Issue 8, (2020) (PubMed).

Wong, Lewis, Doherty, Shi, Cashikar, Amelianchik, Tymchuk, Sullivan, Qian, Covey, Petsko, Holtzman, Paul, Luo: "25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner." in: Journal of neuroinflammation, Vol. 17, Issue 1, pp. 192, (2020) (PubMed).

Hoyle, Redondo-Castro, Cook, Tzeng, Allan, Brough, Lemarchand: "Hallmarks of NLRP3 inflammasome activation are observed in organotypic hippocampal slice culture." in: Immunology, Vol. 161, Issue 1, pp. 39-52, (2020) (PubMed).

Aliases for NLRP3 Antibodies

NLR family pyrin domain containing-like (NLRPL) Antibodies
NLR family pyrin domain containing 3 (NLRP3) Antibodies
NLR family, pyrin domain containing 3 L homeolog (nlrp3.L) Antibodies
NLR family, pyrin domain containing 3 (Nlrp3) Antibodies
agtavprl Antibodies
AGTAVPRL Antibodies
AII Antibodies
AII/AVP Antibodies
avp Antibodies
AVP Antibodies
C1orf7 Antibodies
CIAS1 Antibodies
cias1 Antibodies
Cias1 Antibodies
CLR1.1 Antibodies
FCAS Antibodies
FCU Antibodies
Mmig1 Antibodies
MWS Antibodies
Nalp3 Antibodies
nalp3 Antibodies
NALP3 Antibodies
pypaf1 Antibodies
PYPAF1 Antibodies
Pypaf1 Antibodies
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