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HMGCR Proteins

(3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))
HMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase. Normally in mammalian cells this enzyme is suppressed by cholesterol derived from the internalization and degradation of low density lipoprotein (LDL) via the LDL receptor. Competitive inhibitors of the reductase induce the expression of LDL receptors in the liver, which in turn increases the catabolism of plasma LDL and lowers the plasma concentration of cholesterol, an important determinant of atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].
HMGCR Protein (AA 700-860) (His tag) HMGCR Protein (AA 700-860) (His tag) HMGCR Protein (AA 700-860) (His tag) (ABIN7121607)

HMGCR Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

HMGCR Protein (AA 588-887) (His tag) HMGCR Protein (AA 588-887) (His tag) HMGCR Protein (AA 588-887) (His tag) (ABIN7121606)

HMGCR Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

HMGCR Protein (AA 1-835) (GST tag) HMGCR Protein (AA 1-835) (GST tag) HMGCR Protein (AA 1-835) (GST tag) (ABIN1306814)

HMGCR Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

HMGCR Proteins by Grade

Find HMGCR Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

HMGCR Proteins by Origin

Find HMGCR Proteins for a variety of species such as anti-Human HMGCR, anti-Mouse HMGCR, anti-Rat HMGCR. The species listed below are among those available. Click on a link to go to the corresponding products.

HMGCR Proteins by Source

Here you will find HMGCR Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

HMGCR Proteins by Protein Type

Here you can find HMGCR Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

HMGCR Proteins by Application

Find HMGCR Proteins validated for a specific application such as WB, ELISA, SDS, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular HMGCR Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121607
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121606
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306814
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3111788
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3134765
Quantity 1 mg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7397588
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5709669
Quantity 100 μg
Datasheet Datasheet

Aliases for HMGCR Proteins

3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) Proteins
3-hydroxy-3-methylglutaryl-CoA reductase L homeolog (hmgcr.L) Proteins
3-hydroxy-3-methylglutaryl-Coenzyme A reductase (Hmgcr) Proteins
3-hydroxy-3-methylglutaryl-CoA reductase (Hmgcr) Proteins
HMG Coenzyme A reductase (Hmgcr) Proteins
3-hydroxy-3-methylglutaryl-CoA reductase b (hmgcrb) Proteins
3H3M Proteins
BcDNA:LD15354 Proteins
bro1 Proteins
bs32f05.y1 Proteins
CG10367 Proteins
Clb Proteins
clb Proteins
Dmel\\CG10367 Proteins
DmHMG-CoAr Proteins
Hmg Proteins
hmg-coa-r Proteins
HMG-CoAR Proteins
HmG-CoAR Proteins
hmgc Proteins
HMGCoAR Proteins
HMGCoAr Proteins
HMGCoARr Proteins
HMGCR Proteins
hmgcr Proteins
hmgcr2 Proteins
HMGCR_Dm Proteins
HMGR Proteins
hmgrc Proteins
im:6912716 Proteins
l(3)01152 Proteins
l(3)04684 Proteins
LDLCQ3 Proteins
Red Proteins
zgc:110746 Proteins
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