HMGCR Protein (AA 588-887, partial) (His tag)
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- Target See all HMGCR Proteins
- HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))
- Protein Type
- Recombinant
- Protein Characteristics
- partial, AA 588-887
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This HMGCR protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MTRGPVVRLP RACDSAEVKA WLETSEGFAV IKEAFDSTSR FARLQKLHTS IAGRNLYIRF QSRSGDAMGM NMISKGTEKA LSKLHEYFPE MQILAVSGNY CTDKKPAAIN WIEGRGKSVV CEAVIPAKVV REVLKTTTEA MIEVNINKNL VGSAMAGSIG GYNAHAANIV TAIYIACGQD AAQNVGSSNC ITLMEASGPT NEDLYISCTM PSIEIGTVGG GTNLLPQQAC LQMLGVQGAC KDNPGENARQ LARIVCGTVM AGELSLMAAL AAGHLVKSHM IHNRSKINLQ DLQGACTKKT
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product HMGCR Protein
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3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (AA 700-860) protein (His tag)
HMGCR Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (AA 588-887) protein (His tag)HMGCR Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (AA 1-835) protein (GST tag)HMGCR Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (AA 1-888) protein (Strep Tag)Crystallography grade HMGCR Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (AA 1-887) protein (Strep Tag)Crystallography grade HMGCR Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))
- Alternative Name
- HMDH (HMGCR Products)
- Synonyms
- HMGR Protein, LDLCQ3 Protein, hmg-coa-r Protein, HMG-CoAR Protein, Red Protein, 3H3M Protein, BcDNA:LD15354 Protein, CG10367 Protein, Clb Protein, DmHMG-CoAr Protein, Dmel\\CG10367 Protein, HMGCR Protein, HMGCR_Dm Protein, HMGCoAR Protein, HMGCoARr Protein, HMGCoAr Protein, HmG-CoAR Protein, Hmg Protein, bro1 Protein, bs32f05.y1 Protein, clb Protein, hmgc Protein, hmgcr Protein, hmgrc Protein, l(3)01152 Protein, l(3)04684 Protein, hmgcr2 Protein, im:6912716 Protein, zgc:110746 Protein, 3-hydroxy-3-methylglutaryl-CoA reductase Protein, 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Protein, 3-hydroxy-3-methylglutaryl-Coenzyme A reductase Protein, HMG Coenzyme A reductase Protein, 3-hydroxy-3-methylglutaryl-CoA reductase b Protein, HMGCR Protein, hmgcr.L Protein, Hmgcr Protein, hmgcrb Protein
- Background
- Transmbrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.
- Molecular Weight
- 36.1 kDa
- UniProt
- P04035
- Pathways
- AMPK Signaling, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha
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