HMGCR Protein (AA 1-835) (GST tag)

Catalog No. ABIN1306814

Product Details

Target: HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))

Protein Type: Recombinant

Protein Characteristics: AA 1-835

Origin: Human

Source: Wheat germ

Purification tag / Conjugate: This HMGCR protein is labelled with GST tag.

Application: Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)

Purpose: HMGCR (Human) Recombinant Protein (P01)

Sequence: MLSRLFRMHG LFVASHPWEV IVGTVTLTIC MMSMNMFTGN NKICGWNYEC PKFEEDVLSS DIIILTITRC IAILYIYFQF QNLRQLGSKY ILGIAGLFTI FSSFVFSTVV IHFLDKELTG LNEALPFFLL LIDLSRASTL AKFALSSNSQ DEVRENIARG MAILGPTFTL DALVECLVIG VGTMSGVRQL EIMCCFGCMS VLANYFVFMT FFPACVSLVL ELSRESREGR PIWQLSHFAR VLEEEENKPN PVTQRVKMIM SLGLVLVHAH SRWIADPSPQ NSTADTSKVS LGLDENVSKR IEPSVSLWQF YLSKMISMDI EQVITLSLAL LLAVKYIFFE QTETESTLSL KNPITSPVVT QKKVPDNCCR REPMLVRNNQ KCDSVEEETG INRERKVEVI KPLVAETDTP NRATFVVGNS SLLDTSSVLV TQEPEIELPR EPRPNEECLQ ILGNAEKGAK FLSDAEIIQL VNAKHIPAYK LETLMETHER GVSIRRQLLS KKLSEPSSLQ YLPYRDYNYS LLGGGASSRV LADGMTRGPV VRLPRACDSA EVKAWLETSE GFAVIKEAFD STSRFARLQK LHTSIAGRNL YIRFQSRSGD AMGMNMISKG TEKALSKLHE YFPEMQILAV SGNYCTDKKP AAINWIEGRG KSVVCEAVIP AKVVREVLKT TTEAMIEVNI NKNLVGSAMA GSIGGYNAHA ANIVTAIYIA CGQDAAQNVG SSNCITLMEA SGPTNEDLYI SCTMPSIEIG TVGGGTNLLP QQACLQMLGV QGACKDNPGE NARQLARIVC GTVMAGELSL MAALAAGHLV KSHMIHNRSK INLQDLQGAC TKKTA

Characteristics: Human HMGCR full-length ORF ( AAH33692.1, 1 a.a. - 835 a.a.) recombinant protein with GST-tag at N-terminal.

Purification: in vitro wheat germ expression system

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -80 °C

Storage Comment: Best use within three months from the date of receipt of this protein.

Target Details

Target: HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))

Alternative Name: HMGCR (HMGCR Products)

Synonyms: HMGR Protein, LDLCQ3 Protein, hmg-coa-r Protein, HMG-CoAR Protein, Red Protein, 3H3M Protein, BcDNA:LD15354 Protein, CG10367 Protein, Clb Protein, DmHMG-CoAr Protein, Dmel\\CG10367 Protein, HMGCR Protein, HMGCR_Dm Protein, HMGCoAR Protein, HMGCoARr Protein, HMGCoAr Protein, HmG-CoAR Protein, Hmg Protein, bro1 Protein, bs32f05.y1 Protein, clb Protein, hmgc Protein, hmgcr Protein, hmgrc Protein, l(3)01152 Protein, l(3)04684 Protein, hmgcr2 Protein, im:6912716 Protein, zgc:110746 Protein, 3-hydroxy-3-methylglutaryl-CoA reductase Protein, 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Protein, 3-hydroxy-3-methylglutaryl-Coenzyme A reductase Protein, HMG Coenzyme A reductase Protein, 3-hydroxy-3-methylglutaryl-CoA reductase b Protein, HMGCR Protein, hmgcr.L Protein, Hmgcr Protein, hmgcrb Protein

Background: Gene: 3-hydroxy-3-methylglutaryl-Coenzyme A reductase

Gene ID: 3156

Pathways: AMPK Signaling, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha