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Details for Product No. ABIN1043024

CD82 Molecule (CD82) antibody

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Antigen
Synonyms AA682076, AL023070, C33, IA4, Kai1, Tspan27, R2, 4F9, ST6, GR15, KAI1, SAR2, TSPAN27
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Functional Studies (Func)
Pubmed 5 references available
Catalog no. ABIN1043024
Quantity 0.1 mg
Price
319.44 $   Plus shipping costs $45.00
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Availability Will be delivered in 4 to 5 Business Days
Immunogen C91/PL (human HTLV-1+ T cell line)
Clone C33
Isotype IgG2a
Specificity The antibody C33 reacts with CD82, a widely expressed cell surface protein of the tetraspanin family. CD82 is also found in endosome/lysosome compartments.
Purity Purified
Alternative Name CD82
Background The mouse monoclonal antibody C33 recognizes CD82 (KAI1), a member of the tetraspanin family, which forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules. These complexes influence adhesion, morphology, activation, proliferation and differentiation of B, T and other cells. CD82 regulates cytoskeleton rearrangement and may participate in the turnover of the tetraspanin complex members. Besides in the plasma membrane, CD82 is localized also in endosome/lysosome compartments. Tumour-suppressive roles of CD82 have been demonstrated.
Gene ID 3732
Research Area Cancer, Transcription Factors, CD Antigens, Adaptive Immunity, Surface Receptors of Immune Cells
Comment

CD and Related Antigens (Human)

Restrictions For Research Use only
Buffer Phosphate buffered saline (PBS) pH 7.4
Storage 4 °C
Product cited in: Fukudome, Furuse, Imai et al.: "Identification of membrane antigen C33 recognized by monoclonal antibodies inhibitory to human T-cell leukemia virus type 1 (HTLV-1)-induced syncytium formation: altered glycosylation of C33 antigen in HTLV-1-positive T cells." in: Journal of virology, Vol. 66, Issue 3, pp. 1394-401, 1992 (PubMed).

Imai, Kakizaki, Nishimura et al.: "Molecular analyses of the association of CD4 with two members of the transmembrane 4 superfamily, CD81 and CD82." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 155, Issue 3, pp. 1229-39, 1995 (PubMed).

Imai, Yoshie: "C33 antigen and M38 antigen recognized by monoclonal antibodies inhibitory to syncytium formation by human T cell leukemia virus type 1 are both members of the transmembrane 4 superfamily and associate with each other and with CD4 or CD8 in T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 151, Issue 11, pp. 6470-81, 1994 (PubMed).

Ueda, Ichikawa, Tamaru et al.: "Expression of the KAI1 protein in benign prostatic hyperplasia and prostate cancer." in: The American journal of pathology, Vol. 149, Issue 5, pp. 1435-40, 1996 (PubMed).

Escola, Kleijmeer, Stoorvogel et al.: "Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes." in: The Journal of biological chemistry, Vol. 273, Issue 32, pp. 20121-7, 1998 (PubMed).

Alternatives for antigen "CD82 Molecule (CD82)", type "Antibodies"
Hosts (55), (27)
Reactivities (81), (34), (30), (12), (12), (12), (1)
Applications (44), (22), (21), (18), (18), (10), (6), (5), (2), (2), (2), (1), (1), (1), (1)
Conjugates (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (21), (3), (2), (2), (1), (1)
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